The central role of thrombin in hemostasis JTB Crawley, S Zanardelli, C Chion, DA Lane Journal of thrombosis and haemostasis 5, 95-101, 2007 | 476 | 2007 |
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor JTB Crawley, R de Groot, Y Xiang, BM Luken, DA Lane Blood, The Journal of the American Society of Hematology 118 (12), 3212-3221, 2011 | 378 | 2011 |
Urokinase but not tissue plasminogen activator mediates arterial neointima formation in mice P Carmeliet, L Moons, JM Herbert, J Crawley, F Lupu, R Lijnen, D Collen Circulation research 81 (5), 829-839, 1997 | 277 | 1997 |
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin JTB Crawley, JK Lam, JB Rance, LR Mollica, JS O'Donnell, DA Lane Blood 105 (3), 1085-1093, 2005 | 273 | 2005 |
The haemostatic role of tissue factor pathway inhibitor JTB Crawley, DA Lane Arteriosclerosis, thrombosis, and vascular biology 28 (2), 233-242, 2008 | 217 | 2008 |
High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women HM Andersson, B Siegerink, BM Luken, JTB Crawley, A Algra, DA Lane, ... Blood, The Journal of the American Society of Hematology 119 (6), 1555-1560, 2012 | 194 | 2012 |
Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality JM Gu, JTB Crawley, G Ferrell, F Zhang, W Li, NL Esmon, CT Esmon Journal of Biological Chemistry 277 (45), 43335-43343, 2002 | 178 | 2002 |
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010 | 166 | 2010 |
ADAMTS13 and von Willebrand factor and the risk of myocardial infarction in men CKNK Chion, CJM Doggen, JTB Crawley, DA Lane, FR Rosendaal Blood 109 (5), 1998-2000, 2007 | 164 | 2007 |
Conformational activation of ADAMTS13 K South, BM Luken, JTB Crawley, R Phillips, M Thomas, RF Collins, ... Proceedings of the National Academy of Sciences 111 (52), 18578-18583, 2014 | 161 | 2014 |
Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E–deficient mice A Luttun, F Lupu, E Storkebaum, MF Hoylaerts, L Moons, J Crawley, ... Arteriosclerosis, thrombosis, and vascular biology 22 (3), 499-505, 2002 | 154 | 2002 |
Expression, localization, and activity of tissue factor pathway inhibitor in normal and atherosclerotic human vessels J Crawley, F Lupu, AD Westmuckett, NJ Severs, VV Kakkar, C Lupu Arteriosclerosis, Thrombosis, and Vascular Biology 20 (5), 1362-1373, 2000 | 152 | 2000 |
Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura MR Thomas, R de Groot, MA Scully, JTB Crawley EBioMedicine 2 (8), 942-952, 2015 | 145 | 2015 |
Bombay phenotype is associated with reduced plasma-VWF levels and an increased susceptibility to ADAMTS13 proteolysis JS O'Donnell, TAJ McKinnon, JTB Crawley, DA Lane, MA Laffan Blood 106 (6), 1988-1991, 2005 | 136 | 2005 |
Evidence that high von Willebrand factor and low ADAMTS‐13 levels independently increase the risk of a non‐fatal heart attack JTB Crawley, DA Lane, M Woodward, A Rumley, GDO Lowe Journal of Thrombosis and Haemostasis 6 (4), 583-588, 2008 | 128 | 2008 |
Essential role of the disintegrin-like domain in ADAMTS13 function R de Groot, A Bardhan, N Ramroop, DA Lane, JTB Crawley Blood, The Journal of the American Society of Hematology 113 (22), 5609-5616, 2009 | 120 | 2009 |
Thrombotic thrombocytopenic purpura: basic pathophysiology and therapeutic strategies JTB Crawley, MA Scully Hematology 2013, the American Society of Hematology Education Program Book …, 2013 | 110 | 2013 |
Prevalence of the ADAMTS-13 missense mutation R1060W in late onset adult thrombotic thrombocytopenic purpura RS Camilleri, H Cohen, IJ Mackie, M Scully, RD Starke, JTB Crawley, ... Journal of Thrombosis and Haemostasis 6 (2), 331-338, 2008 | 108 | 2008 |
ADAMTS13 substrate recognition of von Willebrand factor A2 domain S Zanardelli, JTB Crawley, CKNCK Chion, JK Lam, RJS Preston, ... Journal of biological chemistry 281 (3), 1555-1563, 2006 | 106 | 2006 |
Vitamin K–dependent protein S: beyond the protein C pathway B Dahlbäck Seminars in thrombosis and hemostasis 44 (02), 176-184, 2018 | 99 | 2018 |