| Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of … C Burger, OS Gorbatyuk, MJ Velardo, CS Peden, P Williams, S Zolotukhin, ... Molecular Therapy 10 (2), 302-317, 2004 | 909 | 2004 |
| The phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease OS Gorbatyuk, S Li, LF Sullivan, W Chen, G Kondrikova, FP Manfredsson, ... Proceedings of the National Academy of Sciences 105 (2), 763-768, 2008 | 375 | 2008 |
| Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78 MS Gorbatyuk, T Knox, MM LaVail, OS Gorbatyuk, SM Noorwez, ... Proceedings of the National Academy of Sciences 107 (13), 5961-5966, 2010 | 298 | 2010 |
| Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus KH Warrington Jr, OS Gorbatyuk, JK Harrison, SR Opie, S Zolotukhin, ... Journal of virology 78 (12), 6595-6609, 2004 | 275 | 2004 |
| In vivo RNAi-mediated α-synuclein silencing induces nigrostriatal degeneration OS Gorbatyuk, S Li, K Nash, M Gorbatyuk, AS Lewin, LF Sullivan, ... Molecular Therapy 18 (8), 1450-1457, 2010 | 239 | 2010 |
| Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease MS Gorbatyuk, A Shabashvili, W Chen, C Meyers, LF Sullivan, M Salganik, ... Molecular Therapy 20 (7), 1327-1337, 2012 | 203 | 2012 |
| Effect of 2-mercaptoacetate and 2-deoxy-D-glucose administration on the expression of NPY, AGRP, POMC, MCH and hypocretin/orexin in the rat hypothalamus V Sergeyev, C Broberger, O Gorbatyuk, T Hökfelt Neuroreport 11 (1), 117-120, 2000 | 138 | 2000 |
| Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity FP Manfredsson, N Tumer, B Erdos, T Landa, CS Broxson, LF Sullivan, ... Molecular Therapy 17 (6), 980-991, 2009 | 118 | 2009 |
| The molecular chaperone GRP78/BiP as a therapeutic target for neurodegenerative disorders: a mini review MS Gorbatyuk, OS Gorbatyuk Journal of genetic syndrome & gene therapy 4 (2), 2013 | 108 | 2013 |
| ER stress is involved in T17M rhodopsin-induced retinal degeneration MM Kunte, S Choudhury, JF Manheim, VM Shinde, M Miura, VA Chiodo, ... Investigative ophthalmology & visual science 53 (7), 3792-3800, 2012 | 95 | 2012 |
| Salivary PYY: a putative bypass to satiety A Acosta, MD Hurtado, O Gorbatyuk, M La Sala, D Duncan, G Aslanidi, ... PloS one 6 (10), e26137, 2011 | 89 | 2011 |
| Neurodegeneration: keeping ATF4 on a tight leash PM Pitale, O Gorbatyuk, M Gorbatyuk Frontiers in cellular neuroscience 11, 410, 2017 | 72 | 2017 |
| The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons M Salganik, VG Sergeyev, V Shinde, CA Meyers, MS Gorbatyuk, JH Lin, ... Neurobiology of aging 36 (6), 2213-2223, 2015 | 69 | 2015 |
| α-Synuclein expression in rat substantia nigra suppresses phospholipase D2 toxicity and nigral neurodegeneration OS Gorbatyuk, S Li, FN Nguyen, FP Manfredsson, G Kondrikova, ... Molecular Therapy 18 (10), 1758-1768, 2010 | 66 | 2010 |
| Localization of agmatine in vasopressin and oxytocin neurons of the rat hypothalamic paraventricular and supraoptic nuclei OS Gorbatyuk, TA Milner, G Wang, S Regunathan, DJ Reis Experimental neurology 171 (2), 235-245, 2001 | 54 | 2001 |
| Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration S Choudhury, Y Bhootada, O Gorbatyuk, M Gorbatyuk Cell death & disease 4 (3), e528-e528, 2013 | 53 | 2013 |
| Retinal degeneration: Focus on the unfolded protein response M Gorbatyuk, O Gorbatyuk Molecular vision 19, 1985, 2013 | 53 | 2013 |
| Up-regulation of activating transcription factor 4 induces severe loss of dopamine nigral neurons in a rat model of Parkinson’s disease JC Gully, VG Sergeyev, Y Bhootada, H Mendez-Gomez, CA Meyers, ... Neuroscience letters 627, 36-41, 2016 | 50 | 2016 |
| Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis … V Prima, M Tennant, OS Gorbatyuk, N Muzyczka, PJ Scarpace, ... Endocrinology 145 (4), 2035-2045, 2004 | 46 | 2004 |
| Limited ATF4 expression in degenerating retinas with ongoing ER stress promotes photoreceptor survival in a mouse model of autosomal dominant retinitis pigmentosa Y Bhootada, P Kotla, S Zolotukhin, O Gorbatyuk, Z Bebok, M Athar, ... PLoS One 11 (5), e0154779, 2016 | 43 | 2016 |
