Copper-boryl mediated organic synthesis D Hemming, R Fritzemeier, SA Westcott, WL Santos, PG Steel Chemical Society Reviews 47 (19), 7477-7494, 2018 | 273 | 2018 |
Transition Metal-Free Trans Hydroboration of Alkynoic Acid Derivatives: Experimental and Theoretical Studies R Fritzemeier, A Gates, X Guo, Z Lin, WL Santos The Journal of Organic Chemistry 83 (17), 10436-10444, 2018 | 65 | 2018 |
Brønsted Base‐Mediated Regio‐ and Stereoselective trans‐Silaboration of Propargylamides: Access to 1,2‐Vinylborasilanes R Fritzemeier, WL Santos Chemistry–A European Journal 23 (61), 15534-15537, 2017 | 34 | 2017 |
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney S Tanaka, S Zheng, Y Kharel, RG Fritzemeier, T Huang, D Foster, ... Science translational medicine 14 (658), eabj2681, 2022 | 33 | 2022 |
Organocatalytic trans Phosphinoboration of Internal Alkynes RG Fritzemeier, J Nekvinda, CM Vogels, CA Rosenblum, C Slebodnick, ... Angewandte Chemie International Edition 59 (34), 14358-14362, 2020 | 33 | 2020 |
trans-Hydroboration of Propiolamides: Access to Primary and Secondary (E)-β-Borylacrylamides RJ Grams, RG Fritzemeier, C Slebodnick, WL Santos Organic letters 21 (17), 6795-6799, 2019 | 30 | 2019 |
Discovery of in vivo active sphingosine-1-phosphate transporter (Spns2) inhibitors R Fritzemeier, D Foster, A Peralta, M Payette, Y Kharel, T Huang, ... Journal of medicinal chemistry 65 (11), 7656-7681, 2022 | 19 | 2022 |
Molecular mechanism of ligand gating and opening of NMDA receptor TH Chou, M Epstein, RG Fritzemeier, NS Akins, S Paladugu, EZ Ullman, ... Nature 632 (8023), 209-217, 2024 | 8 | 2024 |
Probing the substitution pattern of indole-based scaffold reveals potent and selective sphingosine kinase 2 inhibitors M Congdon, RG Fritzemeier, Y Kharel, AM Brown, V Serbulea, DR Bevan, ... European journal of medicinal chemistry 212, 113121, 2021 | 8 | 2021 |
Route to air and moisture stable β-difluoroboryl acrylamides RG Fritzemeier, EJ Medici, C Szwetkowski, LG Wonilowicz, CD Sibley, ... Organic letters 21 (19), 8053-8057, 2019 | 7 | 2019 |
Neurotherapeutic potential of water-soluble pH-responsive prodrugs of EIDD-036 in traumatic brain injury RG Fritzemeier, AE van der Westhuyzen, M D’Erasmo, SK Sharma, ... Journal of Medicinal Chemistry 66 (8), 5397-5414, 2023 | 6 | 2023 |
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney. Sci Transl Med 14 (658): 2681 S Tanaka, S Zheng, Y Kharel, RG Fritzemeier, T Huang, D Foster, ... | 5 | 2022 |
Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor MP D’Erasmo, NS Akins, P Ma, Y Jing, SA Swanger, SK Sharma, ... ACS Chemical Neuroscience 14 (17), 3059-3076, 2023 | 1 | 2023 |
Mechanisms of Action Underlying Conductance-Modifying Positive Allosteric Modulators of the NMDA Receptor EZ Ullman, RE Perszyk, S Paladugu, RG Fritzemeier, NS Akins, L Jacobs, ... Molecular pharmacology 106 (6), 334-353, 2024 | | 2024 |
Inhibitors of spinster homolog 2 (spns2) for use in therapy KR Lynch, Y Kharel, WL Santos, RG Fritzemeier, AN Peralta US Patent App. 18/044,688, 2023 | | 2023 |
Inhibitors of spinster homolog 2 (spns2) for use in therapy KR Lynch, Y Kharel, WL Santos, RG Fritzemeier, AL Burgio, C Shrader, ... US Patent App. 18/044,686, 2023 | | 2023 |
Unconventional Mechanisms of Novel Positive Allosteric Modulators of NDMA Receptors E Ullman, R Perszyk, J Zhang, N Akins, R Fritzemeier, S Paladugu, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Inhibitors of spinster homolog 2 (spns2) for use in therapy KR Lynch, Y Kharel, WL Santos, A Peralta, RG Fritzemeier, D Foster US Patent App. 17/310,179, 2022 | | 2022 |
trans Addition of BX Reagents Across Polarized Triple Bonds and Development of Sphingosine-1-Phosphate Transport Inhibitors RG Fritzemeier Virginia Tech, 2020 | | 2020 |
Bronsted base mediated regio-and stereoselective silaboration of alkynamides R Fritzemeier, W Santos ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |