| Site-selective modification strategies in antibody–drug conjugates SJ Walsh, JD Bargh, FM Dannheim, AR Hanby, H Seki, AJ Counsell, X Ou, ... Chemical Society Reviews 50 (2), 1305-1353, 2021 | 277 | 2021 |
| A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates SJ Walsh, S Omarjee, WRJD Galloway, TTL Kwan, HF Sore, JS Parker, ... Chemical Science 10 (3), 694-700, 2019 | 128 | 2019 |
| Photocatalytic methods for amino acid modification TA King, JM Kandemir, SJ Walsh, DR Spring Chemical Society Reviews 50 (1), 39-57, 2021 | 106 | 2021 |
| Sulfatase-cleavable linkers for antibody-drug conjugates JD Bargh, SJ Walsh, A Isidro-Llobet, S Omarjee, JS Carroll, DR Spring Chemical Science 11 (9), 2375-2380, 2020 | 71 | 2020 |
| Toolbox of diverse linkers for navigating the cellular efficacy landscape of stapled peptides Y Wu, A Kaur, E Fowler, MM Wiedmann, R Young, WRJD Galloway, ... ACS Chemical Biology 14 (3), 526-533, 2019 | 36 | 2019 |
| General dual functionalisation of biomacromolecules via a cysteine bridging strategy SJ Walsh, J Iegre, H Seki, JD Bargh, HF Sore, JS Parker, JS Carroll, ... Organic & Biomolecular Chemistry 18 (22), 4224-4230, 2020 | 31 | 2020 |
| Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides J Charoenpattarapreeda, YS Tan, J Iegre, SJ Walsh, E Fowler, RS Eapen, ... Chemical Communications 55 (55), 7914-7917, 2019 | 31 | 2019 |
| Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling NS Robertson, SJ Walsh, E Fowler, M Yoshida, SM Rowe, Y Wu, HF Sore, ... Chemical Communications 55 (64), 9499-9502, 2019 | 31 | 2019 |
| Rapid and robust cysteine bioconjugation with vinylheteroarenes H Seki, SJ Walsh, JD Bargh, JS Parker, J Carroll, DR Spring Chemical science 12 (26), 9060-9068, 2021 | 30 | 2021 |
| A dual-enzyme cleavable linker for antibody–drug conjugates JD Bargh, SJ Walsh, N Ashman, A Isidro-Llobet, JS Carroll, DR Spring Chemical Communications 57 (28), 3457-3460, 2021 | 28 | 2021 |
| Efficient and selective antibody modification with functionalised divinyltriazines AJ Counsell, SJ Walsh, NS Robertson, HF Sore, DR Spring Organic & Biomolecular Chemistry 18 (25), 4739-4743, 2020 | 27 | 2020 |
| Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium (II) catalyst TTL Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, ... Chemical Science 8 (5), 3871-3878, 2017 | 23 | 2017 |
| All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading FM Dannheim, SJ Walsh, CT Orozco, AH Hansen, JD Bargh, SE Jackson, ... Chemical Science 13 (30), 8781-8790, 2022 | 17 | 2022 |
| Expeditious total synthesis of hemiasterlin through a convergent multicomponent strategy and its use in targeted cancer therapeutics J Charoenpattarapreeda, SJ Walsh, JS Carroll, DR Spring Angewandte Chemie 132 (51), 23245-23250, 2020 | 17 | 2020 |
| Divinylpyrimidine reagents generate antibody–drug conjugates with excellent in vivo efficacy and tolerability SJ Walsh, S Omarjee, FM Dannheim, DL Couturier, D Bexheti, L Mendil, ... Chemical Communications 58 (12), 1962-1965, 2022 | 13 | 2022 |
| Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, ... Chemical Communications 56 (10), 1529-1532, 2020 | 12 | 2020 |
| Peroxide-cleavable linkers for antibody–drug conjugates N Ashman, JD Bargh, SJ Walsh, RD Greenwood, A Tiberghien, JS Carroll, ... Chemical Communications 59 (13), 1841-1844, 2023 | 8 | 2023 |
| Antibody dual-functionalisation enabled through a modular divinylpyrimidine disulfide rebridging strategy AR Hanby, SJ Walsh, AJ Counsell, N Ashman, KT Mortensen, JS Carroll, ... Chemical Communications 58 (67), 9401-9404, 2022 | 7 | 2022 |
| Disulfide re-bridging reagents for single-payload antibody-drug conjugates TA King, SJ Walsh, M Kapun, T Wharton, S Krajcovicova, MS Glossop, ... Chemical Communications 59 (65), 9868-9871, 2023 | 4 | 2023 |
| LGR5 targeting molecules as therapeutic agents for multiple cancer types HC Chen, N Mueller, K Stott, E Rivers, C Kapeni, CM Sauer, F Beke, ... bioRxiv, 2022.09. 01.506182, 2022 | 1 | 2022 |
