Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis AJ Holland, DW Cleveland Nature reviews Molecular cell biology 10 (7), 478-487, 2009 | 1029 | 2009 |
Once and only once: mechanisms of centriole duplication and their deregulation in disease EA Nigg, AJ Holland Nature reviews Molecular cell biology 19 (5), 297-312, 2018 | 439 | 2018 |
Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals MS Levine, B Bakker, B Boeckx, J Moyett, J Lu, B Vitre, DC Spierings, ... Developmental cell 40 (3), 313-322. e5, 2017 | 361 | 2017 |
Losing balance: the origin and impact of aneuploidy in cancer: ‘Exploring aneuploidy: the significance of chromosomal imbalance’review series AJ Holland, DW Cleveland EMBO reports 13 (6), 501-514, 2012 | 340 | 2012 |
Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells AJ Holland, D Fachinetti, JS Han, DW Cleveland Proceedings of the National Academy of Sciences 109 (49), E3350-E3357, 2012 | 339 | 2012 |
Cep152 interacts with Plk4 and is required for centriole duplication EM Hatch, A Kulukian, AJ Holland, DW Cleveland, T Stearns Journal of Cell Biology 191 (4), 721-729, 2010 | 316 | 2010 |
Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability AJ Holland, W Lan, S Niessen, H Hoover, DW Cleveland Journal of Cell Biology 188 (2), 191-198, 2010 | 299 | 2010 |
Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements AJ Holland, DW Cleveland Nature medicine 18 (11), 1630-1638, 2012 | 295 | 2012 |
A two-step mechanism for epigenetic specification of centromere identity and function D Fachinetti, H Diego Folco, Y Nechemia-Arbely, LP Valente, K Nguyen, ... Nature cell biology 15 (9), 1056-1066, 2013 | 279 | 2013 |
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E Y Kim, AJ Holland, W Lan, DW Cleveland Cell 142 (3), 444-455, 2010 | 277 | 2010 |
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors AD Silk, LM Zasadil, AJ Holland, B Vitre, DW Cleveland, BA Weaver Proceedings of the National Academy of Sciences 110 (44), E4134-E4141, 2013 | 275 | 2013 |
The impact of mitotic errors on cell proliferation and tumorigenesis MS Levine, AJ Holland Genes & development 32 (9-10), 620-638, 2018 | 232 | 2018 |
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells R Gassmann, AJ Holland, D Varma, X Wan, F Çivril, DW Cleveland, ... Genes & development 24 (9), 957-971, 2010 | 224 | 2010 |
Binding of STIL to Plk4 activates kinase activity to promote centriole assembly TC Moyer, KM Clutario, BG Lambrus, V Daggubati, AJ Holland Journal of Cell Biology 209 (6), 863-878, 2015 | 213 | 2015 |
A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis BG Lambrus, V Daggubati, Y Uetake, PM Scott, KM Clutario, G Sluder, ... Journal of Cell Biology 214 (2), 143-153, 2016 | 208 | 2016 |
Mechanism and regulation of centriole and cilium biogenesis DK Breslow, AJ Holland Annual review of biochemistry 88, 691-724, 2019 | 193 | 2019 |
The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation SS Taylor, MIF Scott, AJ Holland Chromosome Research 12, 599-616, 2004 | 191 | 2004 |
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle AJ Holland, D Fachinetti, Q Zhu, M Bauer, IM Verma, EA Nigg, ... Genes & development 26 (24), 2684-2689, 2012 | 172 | 2012 |
Requirements for NuMA in maintenance and establishment of mammalian spindle poles AD Silk, AJ Holland, DW Cleveland Journal of cell biology 184 (5), 677-690, 2009 | 155 | 2009 |
p53 protects against genome instability following centriole duplication failure BG Lambrus, Y Uetake, KM Clutario, V Daggubati, M Snyder, G Sluder, ... Journal of Cell Biology 210 (1), 63-77, 2015 | 154 | 2015 |