Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 3002 | 2009 |
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ... Nature neuroscience 14 (4), 452-458, 2011 | 1224 | 2011 |
Amyotrophic lateral sclerosis-frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria MJ Strong, S Abrahams, LH Goldstein, S Woolley, P Mclaughlin, ... Amyotrophic lateral sclerosis and frontotemporal degeneration 18 (3-4), 153-174, 2017 | 808 | 2017 |
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD … S Al-Sarraj, A King, C Troakes, B Smith, S Maekawa, I Bodi, B Rogelj, ... Acta neuropathologica 122, 691-702, 2011 | 562 | 2011 |
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions C Cserép, B Pósfai, N Lénárt, R Fekete, ZI László, Z Lele, B Orsolits, ... Science 367 (6477), 528-537, 2020 | 505 | 2020 |
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy GG Kovacs, I Ferrer, LT Grinberg, I Alafuzoff, J Attems, H Budka, ... Acta neuropathologica 131, 87-102, 2016 | 447 | 2016 |
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis EM Thompson, T Hielscher, E Bouffet, M Remke, B Luu, S Gururangan, ... The lancet oncology 17 (4), 484-495, 2016 | 365 | 2016 |
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age-and dose-dependent fashion JC Mitchell, P McGoldrick, C Vance, T Hortobagyi, J Sreedharan, B Rogelj, ... Acta neuropathologica 125, 273-288, 2013 | 318 | 2013 |
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules C Vance, EL Scotter, AL Nishimura, C Troakes, JC Mitchell, C Kathe, ... Human molecular genetics 22 (13), 2676-2688, 2013 | 288 | 2013 |
Analysis of alternative splicing associated with aging and neurodegeneration in the human brain JR Tollervey, Z Wang, T Hortobágyi, JT Witten, K Zarnack, M Kayikci, ... Genome research 21 (10), 1572-1582, 2011 | 264 | 2011 |
The C9ORF72 expansion mutation is a common cause of ALS+/− FTD in Europe and has a single founder BN Smith, S Newhouse, A Shatunov, C Vance, S Topp, L Johnson, ... European Journal of Human Genetics 21 (1), 102-108, 2013 | 255 | 2013 |
Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment OA Skrobot, J Attems, M Esiri, T Hortobágyi, JW Ironside, RN Kalaria, ... Brain 139 (11), 2957-2969, 2016 | 252 | 2016 |
Neurodegeneration: the molecular pathology of dementia and movement disorders D Dickson, RO Weller John Wiley & Sons, 2011 | 252 | 2011 |
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer cell 30 (6), 891-908, 2016 | 230 | 2016 |
WNT signaling in activated microglia is proinflammatory C Halleskog, J Mulder, J Dahlström, K Mackie, T Hortobágyi, H Tanila, ... Glia 59 (1), 119-131, 2011 | 230 | 2011 |
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration AL Nishimura, V Župunski, C Troakes, C Kathe, P Fratta, M Howell, ... Brain 133 (6), 1763-1771, 2010 | 223 | 2010 |
Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease J Mulder, M Zilberter, SJ Pasquare, A Alpar, G Schulte, SG Ferreira, ... Brain 134 (4), 1041-1060, 2011 | 209 | 2011 |
Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach E Bereczki, RM Branca, PT Francis, JB Pereira, JH Baek, T Hortobágyi, ... Brain 141 (2), 582-595, 2018 | 203 | 2018 |
Regional multiple pathology scores are associated with cognitive decline in L ewy body dementias DR Howlett, D Whitfield, M Johnson, J Attems, JT O'Brien, D Aarsland, ... Brain pathology 25 (4), 401-408, 2015 | 200 | 2015 |
Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis V Ramaswamy, T Hielscher, SC Mack, A Lassaletta, T Lin, KW Pajtler, ... Journal of clinical oncology 34 (21), 2468-2477, 2016 | 192 | 2016 |