Cancer mutations of the tumor suppressor SPOP disrupt the formation of active, phase-separated compartments JJ Bouchard, JH Otero, DC Scott, E Szulc, EW Martin, N Sabri, D Granata, ... Molecular cell 72 (1), 19-36. e8, 2018 | 318 | 2018 |
Characterization of the free-energy landscapes of proteins by NMR-guided metadynamics D Granata, C Camilloni, M Vendruscolo, A Laio Proceedings of the National Academy of Sciences 110 (17), 6817-6822, 2013 | 156 | 2013 |
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, ... Scientific reports 5 (1), 15449, 2015 | 144 | 2015 |
Free energy surface of an intrinsically disordered protein: comparison between temperature replica exchange molecular dynamics and bias-exchange metadynamics GH Zerze, CM Miller, D Granata, J Mittal Journal of chemical theory and computation 11 (6), 2776-2782, 2015 | 77 | 2015 |
Accurate estimation of the intrinsic dimension using graph distances: Unraveling the geometric complexity of datasets D Granata, V Carnevale Scientific reports 6 (1), 31377, 2016 | 74 | 2016 |
A simple and efficient statistical potential for scoring ensembles of protein structures P Cossio, D Granata, A Laio, F Seno, A Trovato Scientific Reports 2 (1), 351, 2012 | 58 | 2012 |
Dynamic activation and regulation of the mitogen-activated protein kinase p38 GS Kumar, MW Clarkson, MBA Kunze, D Granata, AJ Wand, ... Proceedings of the National Academy of Sciences 115 (18), 4655-4660, 2018 | 57 | 2018 |
Analysis of the destabilization of bacterial membranes by quaternary ammonium compounds: a combined experimental and computational study S Alkhalifa, MC Jennings, D Granata, M Klein, WM Wuest, KPC Minbiole, ... ChemBioChem 21 (10), 1510-1516, 2020 | 53 | 2020 |
Ion channel sensing: are fluctuations the crux of the matter? MA Kasimova, A Yazici, Y Yudin, D Granata, ML Klein, T Rohacs, ... The journal of physical chemistry letters 9 (6), 1260-1264, 2018 | 44 | 2018 |
Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac MN Kinde, V Bondarenko, D Granata, W Bu, KC Grasty, PJ Loll, ... Proceedings of the National Academy of Sciences 113 (48), 13762-13767, 2016 | 38 | 2016 |
Patterns of coevolving amino acids unveil structural and dynamical domains D Granata, L Ponzoni, C Micheletti, V Carnevale Proceedings of the National Academy of Sciences 114 (50), E10612-E10621, 2017 | 37 | 2017 |
A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine MA Kasimova, AT Yazici, Y Yudin, D Granata, ML Klein, T Rohacs, ... Journal of General Physiology 150 (11), 1554-1566, 2018 | 31 | 2018 |
Conserved conformational dynamics determine enzyme activity KR Torgeson, MW Clarkson, D Granata, K Lindorff-Larsen, R Page, ... Science Advances 8 (31), eabo5546, 2022 | 28 | 2022 |
Voltage-gated sodium channels: Evolutionary history and distinctive sequence features MA Kasimova, D Granata, V Carnevale Current topics in membranes 78, 261-286, 2016 | 26 | 2016 |
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites Y Wang, E Yang, MM Wells, V Bondarenko, K Woll, V Carnevale, ... Journal of General Physiology 150 (9), 1317-1331, 2018 | 20 | 2018 |
Native fold and docking pose discrimination by the same residue‐based scoring function E Sarti, D Granata, F Seno, A Trovato, A Laio Proteins: Structure, Function, and Bioinformatics 83 (4), 621-630, 2015 | 18 | 2015 |
Mining protein evolution for insights into mechanisms of voltage-dependent sodium channel auxiliary subunits S Molinarolo, D Granata, V Carnevale, CA Ahern Voltage-gated Sodium Channels: Structure, Function and Channelopathies, 33-49, 2018 | 17 | 2018 |
Sequence and structural conservation reveal fingerprint residues in TRP channels D Cabezas-Bratesco, FA Mcgee, CK Colenso, K Zavala, D Granata, ... Elife 11, e73645, 2022 | 15 | 2022 |
Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation E Yang, D Granata, RG Eckenhoff, V Carnevale, M Covarrubias Journal of General Physiology 150 (9), 1299-1316, 2018 | 15 | 2018 |
Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli L Hamborg, D Granata, JG Olsen, JV Roche, LE Pedersen, AT Nielsen, ... Communications biology 4 (1), 980, 2021 | 13 | 2021 |