| Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase F Leng, J Yu, C Zhang, S Alejo, N Hoang, H Sun, F Lu, H Zhang Nature communications 9 (1), 1641, 2018 | 54 | 2018 |
| Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4DCAF5 ubiquitin ligase C Zhang, F Leng, L Saxena, N Hoang, J Yu, S Alejo, L Lee, D Qi, F Lu, ... Journal Of Biological Chemistry 294 (2), 476-489, 2019 | 43 | 2019 |
| LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase–dependent proteolysis of the stem-cell protein SOX2 C Zhang, N Hoang, F Leng, L Saxena, L Lee, S Alejo, D Qi, A Khal, H Sun, ... Journal Of Biological Chemistry 293 (10), 3663-3674, 2018 | 35 | 2018 |
| KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer M Zhou, PP Venkata, S Viswanadhapalli, B Palacios, S Alejo, Y Chen, ... Breast cancer research and treatment 185, 343-357, 2021 | 31 | 2021 |
| HGF-induced formation of the MET–AXL–ELMO2–DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion W Li, X Xiong, A Abdalla, S Alejo, L Zhu, F Lu, H Sun Journal of Biological Chemistry 293 (40), 15397-15418, 2018 | 27 | 2018 |
| Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair M Wang, W Li, N Tomimatsu, HY Corey, JH Ji, S Alejo, SR Witus, ... Molecular cell 83 (20), 3679-3691. e8, 2023 | 14 | 2023 |
| KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer PP Venkata, Y Chen, S Alejo, Y He, BE Palacios, I Loeffel, J Liu, ... Cancer letters 524, 219-231, 2022 | 14 | 2022 |
| Therapeutic targeting of ovarian cancer stem cells using estrogen receptor beta agonist Y He, S Alejo, PP Venkata, JD Johnson, I Loeffel, UP Pratap, Y Zou, Z Lai, ... International journal of molecular sciences 23 (13), 7159, 2022 | 13 | 2022 |
| Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells GR Sareddy, UP Pratap, PP Venkata, M Zhou, S Alejo, S Viswanadhapalli, ... Stem Cells 39 (5), 536-550, 2021 | 13 | 2021 |
| Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma S Alejo, BE Palacios, PP Venkata, Y He, W Li, JD Johnson, Y Chen, ... Neuro-oncology 25 (7), 1249-1261, 2023 | 11 | 2023 |
| Pharmacological inhibition of KDM1A/LSD1 enhances estrogen receptor beta-mediated tumor suppression in ovarian cancer PP Venkata, S Jayamohan, Y He, S Alejo, JD Johnson, BE Palacios, ... Cancer Letters 575, 216383, 2023 | 7 | 2023 |
| Lysine-specific demethylase 1 as a therapeutic cancer target: Observations from preclinical study JD Johnson, S Alejo, S Jayamohan, GR Sareddy Expert opinion on therapeutic targets 27 (12), 1177-1188, 2023 | 5 | 2023 |
| KDM1A/LSD1 inhibition enhances chemotherapy response in ovarian cancer Y Chen, JD Johnson, S Jayamohan, Y He, PP Venkata, D Jamwal, ... Molecular Carcinogenesis 63 (10), 2026-2039, 2024 | | 2024 |
| DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis Y Huang, W Li, T Foo, JH Ji, B Wu, N Tomimatsu, Q Fang, B Gao, M Long, ... Nature Communications 15 (1), 7081, 2024 | | 2024 |
| Abstract PO4-28-08: Unraveling the Role of BRCA1-BARD1 E3 Ubiquitin Ligase in DNA Repair: A Promise for Enhanced Chemotherapy Outcomes W Li, M Wang, N Tomimatsu, JH Ji, S Alejo, GR Sareddy, S Burma, ... Cancer Research 84 (9_Supplement), PO4-28-08-PO4-28-08, 2024 | | 2024 |
| PELP1 inhibition enhances the therapeutic efficacy of topoisomerase inhibitors in triple-negative breast cancer KM Nassar, JR Sanchez, DM Panneerdoss, B Ebrahimi, Y Xue, UP Pratap, ... Cancer Research 84 (6_Supplement), 2099-2099, 2024 | | 2024 |
| KDM1A/LSD1 inhibition enhances estrogen receptor beta mediated tumor suppression in ovarian cancer PP Venkata, S Jayamohan, Y He, S Alejo, JD Johnson, UP Pratap, ... Cancer Research 83 (7_Supplement), 3081-3081, 2023 | | 2023 |
| 301 Inhibition of lysine-specific histone demethylase 1A (KDM1A/LSD1) attenuates DNA double strand break repair and enhances efficacy of temozolomide in glioblastoma S Alejo, B Palacios, PP Venkata, Y He, W Li, J Johnson, S Jayamohan, ... Journal of Clinical and Translational Science 7 (s1), 90-90, 2023 | | 2023 |
| Reticulocalbin 3 Is a Novel Mediator of Glioblastoma Progression Y He, S Alejo, JD Johnson, S Jayamohan, GR Sareddy Cancers 15 (7), 2008, 2023 | | 2023 |
| KDM1A inhibition augment ER stress inducers efficacy to reduce glioblastoma stemness Y He, PP Venkata, S Alejo, Y Chen, B Palacios, G Gray, UP Pratap, ... Cancer Research 81 (13_Supplement), 2026-2026, 2021 | | 2021 |
Gangadhara Reddy SareddyAssociate Professor, University of Texas Health San Antonio在 uthscsa.edu 的电子邮件经过验证
