| WOMBAT: world of molecular bioactivity M Olah, M Mracec, L Ostopovici, R Rad, A Bora, N Hadaruga, I Olah, ... Chemoinformatics in drug discovery 1, 223-239, 2004 | 177 | 2004 |
| DrugCentral 2021 supports drug discovery and repositioning S Avram, CG Bologa, J Holmes, G Bocci, TB Wilson, DT Nguyen, ... Nucleic acids research 49 (D1), D1160-D1169, 2021 | 160 | 2021 |
| A crowdsourcing evaluation of the NIH chemical probes TI Oprea, CG Bologa, S Boyer, RF Curpan, RC Glen, AL Hopkins, ... Nature chemical biology 5 (7), 441-447, 2009 | 140 | 2009 |
| The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1 JS Lewis-Wambi, H Kim, R Curpan, R Grigg, MA Sarker, VC Jordan Molecular pharmacology 80 (4), 610-620, 2011 | 130 | 2011 |
| Lead-like, drug-like or “Pub-like”: how different are they? TI Oprea, TK Allu, DC Fara, RF Rad, L Ostopovici, CG Bologa Journal of Computer-Aided Molecular Design 21, 113-119, 2007 | 130 | 2007 |
| ChemProt: a disease chemical biology database O Taboureau, SK Nielsen, K Audouze, N Weinhold, D Edsgärd, FS Roque, ... Nucleic acids research 39 (suppl_1), D367-D372, 2010 | 128 | 2010 |
| WOMBAT and WOMBAT‐PK: bioactivity databases for lead and drug discovery M Olah, R Rad, L Ostopovici, A Bora, N Hadaruga, D Hadaruga, ... Chemical biology: from small molecules to systems biology and drug design 1 …, 2007 | 122 | 2007 |
| Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells S Sengupta, I Obiorah, PY Maximov, R Curpan, VC Jordan British journal of pharmacology 169 (1), 167-178, 2013 | 111 | 2013 |
| Structure− function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen PY Maximov, CB Myers, RF Curpan, JS Lewis-Wambi, VC Jordan Journal of medicinal chemistry 53 (8), 3273-3283, 2010 | 57 | 2010 |
| Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs R Burai, C Ramesh, M Shorty, R Curpan, C Bologa, LA Sklar, T Oprea, ... Organic & biomolecular chemistry 8 (9), 2252-2259, 2010 | 53 | 2010 |
| Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators VC Jordan, R Curpan, PY Maximov Journal of the National Cancer Institute 107 (6), djv075, 2015 | 50 | 2015 |
| Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt® high-throughput flow cytometry system MK Haynes, JJ Strouse, A Waller, A Leitao, RF Curpan, C Bologa, ... SLAS Discovery 14 (6), 596-609, 2009 | 42 | 2009 |
| The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy P Fan, PY Maximov, RF Curpan, B Abderrahman, VC Jordan Molecular and cellular endocrinology 418, 245-263, 2015 | 39 | 2015 |
| Endoxifen, 4-hydroxytamoxifen and an estrogenic derivative modulate estrogen receptor complex mediated apoptosis in breast cancer PY Maximov, B Abderrahman, SW Fanning, S Sengupta, P Fan, ... Molecular pharmacology 94 (2), 812-822, 2018 | 32 | 2018 |
| Structural determinants of the alpha2 adrenoceptor subtype selectivity L Ostopovici-Halip, R Curpăn, M Mracec, CG Bologa Journal of Molecular Graphics and Modelling 29 (8), 1030-1038, 2011 | 30 | 2011 |
| Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer I Obiorah, S Sengupta, R Curpan, VC Jordan Molecular pharmacology 85 (5), 789-799, 2014 | 29 | 2014 |
| Origin of uterine fibroids: conversion of myometrial stem cells to tumor-initiating cells H Elkafas, Y Qiwei, A Al-Hendy Seminars in reproductive medicine 35 (06), 481-486, 2017 | 28 | 2017 |
| High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry RF Curpan, PC Simons, D Zhai, SM Young, MB Carter, CG Bologa, ... Assay and drug development technologies 9 (5), 465-474, 2011 | 27 | 2011 |
| A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers PY Maximov, B Abderrahman, RF Curpan, YM Hawsawi, P Fan, ... Endocrine-related cancer 25 (2), R83-R113, 2018 | 26 | 2018 |
| DrugCentral 2023 extends human clinical data and integrates veterinary drugs S Avram, TB Wilson, R Curpan, L Halip, A Borota, A Bora, CG Bologa, ... Nucleic acids research 51 (D1), D1276-D1287, 2023 | 25 | 2023 |
Tudor OpreaCEO, Expert Systems Inc在 expertsystems.inc 的电子邮件经过验证
