| pH-gated succinate secretion regulates muscle remodeling in response to exercise A Reddy, LHM Bozi, OK Yaghi, EL Mills, H Xiao, HE Nicholson, ... Cell 183 (1), 62-75. e17, 2020 | 195 | 2020 |
| Cyclin D–CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB AE Schade, MG Oser, HE Nicholson, JA DeCaprio Oncogene 38 (25), 4962-4976, 2019 | 69 | 2019 |
| HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species HE Nicholson, Z Tariq, BE Housden, RB Jennings, LA Stransky, ... Science signaling 12 (601), eaay0482, 2019 | 65 | 2019 |
| Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: structure-activity relationships of 6-acetyl-3-(4-(4-(4-fluorophenyl) piperazin-1-yl) butyl … HE Nicholson, WF Alsharif, AB Comeau, C Mesangeau, S Intagliata, ... Journal of Pharmacology and Experimental Therapeutics 368 (2), 272-281, 2019 | 24 | 2019 |
| Sigma-2 receptors play a role in cellular metabolism: stimulation of glycolytic hallmarks by CM764 in human SK-N-SH neuroblastoma H Nicholson, C Mesangeau, CR McCurdy, WD Bowen Journal of Pharmacology and Experimental Therapeutics 356 (2), 232-243, 2016 | 24 | 2016 |
| Characterization of CM572, a selective irreversible partial agonist of the sigma-2 receptor with antitumor activity H Nicholson, A Comeau, C Mesangeau, CR McCurdy, WD Bowen Journal of Pharmacology and Experimental Therapeutics 354 (2), 203-212, 2015 | 24 | 2015 |
| Synthetic lethality screens using RNAi in combination with CRISPR-based knockout in Drosophila cells BE Housden, HE Nicholson, N Perrimon Bio-protocol 7 (3), e2119-e2119, 2017 | 16 | 2017 |
| Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity CZ Liu, M Mottinelli, HE Nicholson, BM McVeigh, NK Wong, CR McCurdy, ... European journal of pharmacology 906, 174263, 2021 | 8 | 2021 |
| Sigma-2 receptor-induced cell death: a novel approach to triple-negative breast cancer treatment Z Liu, HE Nicholson, WD Bowen Cancer Research 75 (15_Supplement), 5428-5428, 2015 | 4 | 2015 |
| Loss of CDK4/6 Activity Is Synthetic Lethal with VHL Inactivation in Clear Cell Renal Cell Carcinoma HE Nicholson, B Housden, N Perrimon, WG Kaelin Jr The FASEB Journal 33 (S1), 674.9-674.9, 2019 | 2 | 2019 |
| LIG1 inactivation selectively inhibits growth of BRCA1 mutant cells in vitro and in vivo L Martires, LG Ahronian, C Pratt, N Das, X Zhang, DA Whittington, ... Cancer Research 84 (6_Supplement), 3363-3363, 2024 | | 2024 |
| Abstract C124: HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species H Nicholson, B Housden, N Perrimon, WG Kaelin Molecular Cancer Therapeutics 18 (12_Supplement), C124-C124, 2019 | | 2019 |
| Differential sigma-2 receptor-mediated metabolic stimulative and apoptotic effects of monovalent CM571 and its homo-bivalent counterpart, MAM03055A CZ Liu, BM McVeigh, M Mottinelli, HE Nicholson, CR McCurdy, ... Cancer Research 79 (13_Supplement), 1294-1294, 2019 | | 2019 |
| Identification and characterization of MAM03055A, a novel bivalent sigma-2 receptor agonist CZ Liu, M Mottinelli, HE Nicholson, E Zhong, CR McCurdy, WD Bowen Cancer Research 78 (13_Supplement), 1671-1671, 2018 | | 2018 |
| Structural changes to SN79 result in ligands that stimulate a metabolic function of sigma-2 receptors HE Nicholson, W Alsharif, CR McCurdy, WD Bowen Cancer Research 76 (14_Supplement), 3804-3804, 2016 | | 2016 |
| Evaluation of structural changes in SN79-derived sigma-2 receptor modulators: effect on apoptotic efficacy in SK-N-SH neuroblastoma HE Nicholson, W Alsharif, CR McCurdy, WD Bowen Cancer Research 75 (15_Supplement), 2440-2440, 2015 | | 2015 |
| Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor activation in 3D culture T Chou, M Jacobs, H Nicholson, WD Bowen Cancer Research 75 (15_Supplement), 1699-1699, 2015 | | 2015 |
| Characterization of CM-572 and CM-769: Novel irreversible modulators of sigma-2 receptor function HE Nicholson, PL Chia, A Comeau, C Mesangeau, C McCurdy, ... Cancer Research 74 (19_Supplement), 3237-3237, 2014 | | 2014 |
| Development of selective irreversible antagonists for sigma-2 receptors. H Nicholson, A Comeau, C Mesangeau, CR McCurdy, WD Bowen Cancer Research 73 (8_Supplement), 2242-2242, 2013 | | 2013 |
