Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770 F Van Goor, S Hadida, PDJ Grootenhuis, B Burton, D Cao, T Neuberger, ... Proceedings of the National Academy of Sciences 106 (44), 18825-18830, 2009 | 1370 | 2009 |
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809 F Van Goor, S Hadida, PDJ Grootenhuis, B Burton, JH Stack, KS Straley, ... Proceedings of the National Academy of Sciences 108 (46), 18843-18848, 2011 | 1228 | 2011 |
Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis Mutation (∗) S Sato, CL Ward, ME Krouse, JJ Wine, RR Kopito Journal of Biological Chemistry 271 (2), 635-638, 1996 | 657 | 1996 |
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion BQ Shen, WE Finkbeiner, JJ Wine, RJ Mrsny, JH Widdicombe American Journal of Physiology-Lung Cellular and Molecular Physiology 266 (5 …, 1994 | 451 | 1994 |
Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis X Sun, H Sui, JT Fisher, Z Yan, X Liu, HJ Cho, NS Joo, Y Zhang, W Zhou, ... The Journal of clinical investigation 120 (9), 3149-3160, 2010 | 413 | 2010 |
The organization of escape behaviour in the crayfish JJ Wine, FB Krasne Journal of Experimental Biology 56 (1), 1-18, 1972 | 384 | 1972 |
The genesis of cystic fibrosis lung disease JJ Wine The Journal of clinical investigation 103 (3), 309-312, 1999 | 369 | 1999 |
A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies JA Wagner, IB Nepomuceno, AH Messner, ML Moran, EP Batson, ... Human gene therapy 13 (11), 1349-1359, 2002 | 314 | 2002 |
Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus JA Wagner, T Reynolds, ML Moran, RB Moss, JJ Wine, TR Flotte, ... The Lancet 351 (9117), 1702-1703, 1998 | 275 | 1998 |
Submucosal glands and airway defense JJ Wine, NS Joo Proceedings of the American Thoracic Society 1 (1), 47-53, 2004 | 265 | 2004 |
Safety and Biological Efficacy of an Adeno‐Associated Virus Vector–Cystic Fibrosis Transmembrane Regulator (AAV‐CFTR) in the Cystic Fibrosis Maxillary Sinus JA Wagner, AH Messner, ML Moran, R Daifuku, K Kouyama, JK Desch, ... The Laryngoscope 109 (2), 266-274, 1999 | 255 | 1999 |
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na+] and pH but elevated viscosity S Jayaraman, NS Joo, B Reitz, JJ Wine, AS Verkman Proceedings of the National Academy of Sciences 98 (14), 8119-8123, 2001 | 247 | 2001 |
The structural basis of an innate behavioural pattern JJ Wine Journal of Experimental Biology 112 (1), 283-319, 1984 | 235 | 1984 |
The cellular organization of crayfish escape behavior JJ Wine, FB Krasne The biology of Crustacea 4, 241-292, 1982 | 233 | 1982 |
Failure of the cystic fibrosis transmembrane conductance regulator to conduct ATP MM Reddy, PM Quinton, C Haws, JJ Wine, R Grygorczyk, JA Tabcharani, ... Science 271 (5257), 1876-1879, 1996 | 220 | 1996 |
Airway gland structure and function JH Widdicombe, JJ Wine Physiological reviews 95 (4), 1241-1319, 2015 | 219 | 2015 |
CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl-conductance C Haws, WE Finkbeiner, JH Widdicombe, JJ Wine American Journal of Physiology-Lung Cellular and Molecular Physiology 266 (5 …, 1994 | 202 | 1994 |
Swelling-induced and depolarization-induced C1-channels in normal and cystic fibrosis epithelial cells CK Solc, JJ Wine American Journal of Physiology-Cell Physiology 261 (4), C658-C674, 1991 | 190 | 1991 |
Delta F508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines CM Haws, IB Nepomuceno, ME Krouse, H Wakelee, T Law, Y Xia, ... American Journal of Physiology-Cell Physiology 270 (5), C1544-C1555, 1996 | 181 | 1996 |
Absent secretion to vasoactive intestinal peptide in cystic fibrosis airway glands NS Joo, T Irokawa, JV Wu, RC Robbins, RI Whyte, JJ Wine Journal of Biological Chemistry 277 (52), 50710-50715, 2002 | 143 | 2002 |