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Renee C Ryals
Renee C Ryals
在 ohsu.edu 的电子邮件经过验证
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引用次数
引用次数
年份
The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver
AT Martino, M Suzuki, DM Markusic, I Zolotukhin, RC Ryals, B Moghimi, ...
Blood, The Journal of the American Society of Hematology 117 (24), 6459-6468, 2011
2402011
Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors
CN Kay, RC Ryals, GV Aslanidi, SH Min, Q Ruan, J Sun, FM Dyka, ...
PloS one 8 (4), e62097, 2013
2012013
Lipid nanoparticles for delivery of messenger RNA to the back of the eye
S Patel, RC Ryals, KK Weller, ME Pennesi, G Sahay
Journal of Controlled Release 303, 91-100, 2019
1772019
The human rhodopsin kinase promoter in an AAV5 vector confers rod-and cone-specific expression in the primate retina
SE Boye, JJ Alexander, SL Boye, CD Witherspoon, KJ Sandefer, ...
Human gene therapy 23 (10), 1101-1115, 2012
1362012
The effects of PEGylation on LNP based mRNA delivery to the eye
RC Ryals, S Patel, C Acosta, M McKinney, ME Pennesi, G Sahay
PLoS One 15 (10), e0241006, 2020
1302020
Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse
SE Boye, SL Boye, J Pang, R Ryals, D Everhart, Y Umino, AW Neeley, ...
PloS one 5 (6), e11306, 2010
1192010
Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of MERTK Associated Retinitis Pigmentosa
TJ Conlon, WT Deng, K Erger, T Cossette, J Pang, R Ryals, N Clément, ...
Human gene therapy Clinical development 24 (1), 23-28, 2013
1062013
Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency
J Pang, SE Boye, B Lei, SL Boye, D Everhart, R Ryals, Y Umino, B Rohrer, ...
Gene therapy 17 (7), 815-826, 2010
812010
Long-term preservation of cone photoreceptors and restoration of cone function by gene therapy in the guanylate cyclase-1 knockout (GC1KO) mouse
SL Boye, T Conlon, K Erger, R Ryals, A Neeley, T Cossette, J Pang, ...
Investigative ophthalmology & visual science 52 (10), 7098-7108, 2011
782011
Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates
M Herrera-Barrera, RC Ryals, M Gautam, A Jozic, M Landry, T Korzun, ...
Science advances 9 (2), eadd4623, 2023
722023
Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines
RC Ryals, SL Boye, A Dinculescu, WW Hauswirth, SE Boye
Molecular vision 17, 1090, 2011
612011
Long-term characterization of retinal degeneration in Royal College of Surgeons rats using spectral-domain optical coherence tomography
RC Ryals, MD Andrews, S Datta, AS Coyner, CM Fischer, Y Wen, ...
Investigative ophthalmology & visual science 58 (3), 1378-1386, 2017
592017
Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy
SE Boye, WC Huang, AJ Roman, A Sumaroka, SL Boye, RC Ryals, ...
PLoS One 9 (3), e92928, 2014
332014
Sarpogrelate, a 5-HT2A receptor antagonist, protects the retina from light-induced retinopathy
BE Tullis, RC Ryals, AS Coyner, MJ Gale, N Alex, K Cristy, R Dain, S Wrik, ...
Investigative ophthalmology & visual science 56 (8), 4560-4569, 2015
272015
Cone specific promoter for use in gene therapy of retinal degenerative diseases
FM Dyka, SL Boye, RC Ryals, VA Chiodo, SE Boye, WW Hauswirth
Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 695-701, 2014
262014
γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines
X Qi, J Cai, Q Ruan, L Liu, SL Boye, Z Chen, WW Hauswirth, RC Ryals, ...
Investigative ophthalmology & visual science 53 (2), 574-585, 2012
182012
Strategies for non-viral vectors targeting organs beyond the liver
J Kim, Y Eygeris, RC Ryals, A Jozić, G Sahay
Nature nanotechnology 19 (4), 428-447, 2024
162024
Retinal neuroprotective effects of flibanserin, an FDA-approved dual serotonin receptor agonist-antagonist
AS Coyner, RC Ryals, CA Ku, CM Fischer, RC Patel, S Datta, P Yang, ...
PloS one 11 (7), e0159776, 2016
152016
Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin
BP Rossmiller, RC Ryals, AS Lewin
Rhodopsin: Methods and Protocols, 391-410, 2015
152015
Lipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina
M Gautam, A Jozic, GLN Su, M Herrera-Barrera, A Curtis, S Arrizabalaga, ...
Nature communications 14 (1), 6468, 2023
142023
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