| Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis JK Rathkey, J Zhao, Z Liu, Y Chen, J Yang, HC Kondolf, BL Benson, ... Science immunology 3 (26), eaat2738, 2018 | 448 | 2018 |
| IL-17 receptor–based signaling and implications for disease X Li, R Bechara, J Zhao, MJ McGeachy, SL Gaffen Nature immunology 20 (12), 1594-1602, 2019 | 359 | 2019 |
| Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells Z Kang, C Wang, J Zepp, L Wu, K Sun, J Zhao, U Chandrasekharan, ... Nature neuroscience 16 (10), 1401-1408, 2013 | 235 | 2013 |
| A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis L Wu, X Chen, J Zhao, B Martin, JA Zepp, JS Ko, C Gu, G Cai, W Ouyang, ... Journal of Experimental Medicine 212 (10), 1571-1587, 2015 | 213 | 2015 |
| The role of interleukin-17 in tumor development and progression J Zhao, X Chen, T Herjan, X Li Journal of Experimental Medicine 217 (1), e20190297, 2019 | 188 | 2019 |
| LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection W Liu, X Liu, YU Li, J Zhao, Z Liu, Z Hu, Y Wang, Y Yao, AW Miller, B Su, ... Journal of Experimental Medicine 214 (10), 3051-3066, 2017 | 167 | 2017 |
| T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis BN Martin, C Wang, C Zhang, Z Kang, MF Gulen, JA Zepp, J Zhao, G Bian, ... Nature immunology 17 (5), 583-592, 2016 | 165 | 2016 |
| Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis K Bulek, J Zhao, Y Liao, N Rana, D Corridoni, A Antanaviciute, X Chen, ... The Journal of clinical investigation 130 (8), 4218-4234, 2020 | 149 | 2020 |
| Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis Y Liao, J Zhao, K Bulek, F Tang, X Chen, G Cai, S Jia, PL Fox, E Huang, ... Nature communications 11 (1), 900, 2020 | 139 | 2020 |
| GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis N Rana, G Privitera, HC Kondolf, K Bulek, S Lechuga, C De Salvo, ... Cell 185 (2), 283-298. e17, 2022 | 117 | 2022 |
| IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling T Herjan, L Hong, J Bubenik, K Bulek, W Qian, C Liu, X Li, X Chen, ... Nature immunology 19 (4), 354-365, 2018 | 113 | 2018 |
| IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells X Chen, G Cai, C Liu, J Zhao, C Gu, L Wu, TA Hamilton, C Zhang, J Ko, ... Journal of Experimental Medicine 216 (1), 195-214, 2019 | 100 | 2019 |
| IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression C Wang, CJ Zhang, BN Martin, K Bulek, Z Kang, J Zhao, G Bian, ... Nature Communications 8 (1), 15508, 2017 | 98 | 2017 |
| MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases M Yu, H Zhou, J Zhao, N Xiao, S Roychowdhury, D Schmitt, B Hu, ... Journal of Experimental Medicine 211 (5), 887-907, 2014 | 88 | 2014 |
| IRAKM‐Mincle axis links cell death to inflammation: pathophysiological implications for chronic alcoholic liver disease H Zhou, M Yu, J Zhao, BN Martin, S Roychowdhury, MR McMullen, ... Hepatology 64 (6), 1978-1993, 2016 | 77 | 2016 |
| TRAF regulation of IL-17 cytokine signaling S Swaidani, C Liu, J Zhao, K Bulek, X Li Frontiers in immunology 10, 1293, 2019 | 68 | 2019 |
| IL-17A–induced PLET1 expression contributes to tissue repair and colon tumorigenesis JA Zepp, J Zhao, C Liu, K Bulek, L Wu, X Chen, Y Hao, Z Wang, X Wang, ... The Journal of Immunology 199 (11), 3849-3857, 2017 | 63 | 2017 |
| Human colon tumors express a dominant-negative form of SIGIRR that promotes inflammation and colitis-associated colon cancer in mice J Zhao, K Bulek, MF Gulen, JA Zepp, G Karagkounis, BN Martin, H Zhou, ... Gastroenterology 149 (7), 1860-1871. e8, 2015 | 50 | 2015 |
| IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes H Zhou, H Wang, M Yu, RC Schugar, W Qian, F Tang, W Liu, H Yang, ... Nature immunology 21 (10), 1219-1231, 2020 | 42 | 2020 |
| IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs H Zhou, K Bulek, X Li, T Herjan, M Yu, W Qian, H Wang, G Zhou, X Chen, ... Elife 6, e29630, 2017 | 36 | 2017 |
