Ectonucleoside triphosphate diphosphohydrolase-3 antibody targets adult human pancreatic β cells for in vitro and in vivo analysis DC Saunders, M Brissova, N Phillips, S Shrestha, JT Walker, ... Cell metabolism 29 (3), 745-754. e4, 2019 | 70 | 2019 |
The human islet: mini-organ with mega-impact JT Walker, DC Saunders, M Brissova, AC Powers Endocrine reviews 42 (5), 605-657, 2021 | 69 | 2021 |
Tacrolimus-and sirolimus-induced human β cell dysfunction is reversible and preventable C Dai, JT Walker, A Shostak, A Padgett, E Spears, S Wisniewski, ... JCI insight 5 (1), 2020 | 59 | 2020 |
Lipid droplet accumulation in human pancreatic islets is dependent on both donor age and health X Tong, C Dai, JT Walker, GG Nair, A Kennedy, RM Carr, M Hebrok, ... Diabetes 69 (3), 342-354, 2020 | 47 | 2020 |
Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells JT Walker, R Haliyur, HA Nelson, M Ishahak, G Poffenberger, ... JCI insight 5 (10), 2020 | 42 | 2020 |
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells S Shrestha, DC Saunders, JT Walker, J Camunas-Soler, XQ Dai, ... JCI Insight 6 (18), e151621, 2021 | 27 | 2021 |
Dapagliflozin does not directly affect human α or β cells C Dai, JT Walker, A Shostak, Y Bouchi, G Poffenberger, NJ Hart, ... Endocrinology 161 (8), bqaa080, 2020 | 14 | 2020 |
Genetic risk converges on regulatory networks mediating early type 2 diabetes. JT Walker, DC Saunders, V Rai, HH Chen, P Orchard, C Dai, YD Pettway, ... Nature, 2023 | 10 | 2023 |
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes JT Walker, DC Saunders, V Rai, C Dai, P Orchard, AL Hopkirk, ... BioRxiv, 2021.12. 16.466282, 2021 | 9 | 2021 |
Integrated analysis of the pancreas and islets reveals unexpected findings in human male with type 1 diabetes R Haliyur, JT Walker, M Sanyoura, CV Reihsmann, S Shrestha, ... Journal of the Endocrine Society 5 (12), bvab162, 2021 | 1 | 2021 |
New Insights into the Molecular Mechanisms of Islet Dysfunction in Human Diabetes JT Walker | 1 | 2021 |
Investigating Islet Abnormalities and Function with a Pseudoislet Protocol (Video)| JoVE TM Richardson, YD Pettway, JT Walker, HA Nelson, M Ishahak, ... JoVE (Journal of Visualized Experiments), e65259, 2023 | | 2023 |
231-OR: Reduced NKX2-2 Expression Enhances Insulin Secretion by Primary Human ß-Cells YD PETTWAY, J WALKER, C DAI, R ARAMANDLA, AL HOPKIRK, ... Diabetes 72 (Supplement_1), 2023 | | 2023 |
367-OR: Elucidating Mechanisms of α-Cell Dysfunction in T1D YD Pettway, C Dai, TM Richardson, JT Walker, R Aramandla, ... Diabetes 71 (Supplement_1), 2022 | | 2022 |
44-OR: Human Pseudo Islets Reveal Differential Effects of Gq Signaling in ß Cells in Low and High Glucose JT WALKER, R HALIYUR, R ARAMANDLA, G POFFENBERGER, ... Diabetes 68 (Supplement_1), 2019 | | 2019 |
107-OR: Profiling of Human Pancreatic Islets by Single Cell Transcriptomics Reveals α-and ß-Cell Subpopulations S Shrestha, DC Saunders, JT Walker, R Haliyur, G Poffenberger, ... Diabetes 68 (Supplement_1), 2019 | | 2019 |
Pancreatic Islets in Short Duration Type 2 Diabetes (T2D) Show Macrophage Infiltration and Increased Inflammatory Signaling JT Walker, S Shrestha, N Prasad, T Richardson, R Aramandla, ... Diabetes 67 (Supplement_1), 2018 | | 2018 |
Pancreatic Islets in Short-Duration Type 2 Diabetes Have Secretory Dysfunction, Variable Amyloid Accumulation, and Altered Islet-Enriched Transcription Factor Expression JT Walker, D Saunders, S Shrestha, N Prasad, SE Levy, R Aramandla, ... DIABETES 66, A577-A577, 2017 | | 2017 |
Integrated human pseudoislet system and microfluidic platform demonstrates differences in G-protein-coupled-receptor signaling in islet cells JT Walker, AC Powers, M Brissova Insulin 2, 4, 0 | | |