A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1 B Zhao, F Du, P Xu, C Shu, B Sankaran, SL Bell, M Liu, Y Lei, X Gao, X Fu, ... Nature 569 (7758), 718-722, 2019 | 278 | 2019 |
NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation X Lahaye, M Gentili, A Silvin, C Conrad, L Picard, M Jouve, E Zueva, ... Cell 175 (2), 488-501. e22, 2018 | 202 | 2018 |
Structure and function of the Zika virus full-length NS5 protein B Zhao, G Yi, F Du, YC Chuang, RC Vaughan, B Sankaran, CC Kao, P Li Nature communications 8 (1), 1-9, 2017 | 195 | 2017 |
The molecular basis of tight nuclear tethering and inactivation of cGAS B Zhao, P Xu, CM Rowlett, T Jing, O Shinde, Y Lei, AP West, WR Liu, P Li Nature 587 (7835), 673-677, 2020 | 177 | 2020 |
Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins B Zhao, C Shu, X Gao, B Sankaran, F Du, CL Shelton, AB Herr, JY Ji, P Li Proceedings of the National Academy of Sciences 113 (24), E3403-E3412, 2016 | 163 | 2016 |
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis CG Weindel, EL Martinez, X Zhao, CJ Mabry, SL Bell, KJ Vail, ... Cell 185 (17), 3214-3231. e23, 2022 | 144 | 2022 |
A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors KS Yang, XR Ma, Y Ma, YR Alugubelli, DA Scott, EC Vatansever, ... ChemMedChem, 2020 | 106 | 2020 |
Oligoadenylate-synthetase-family protein OASL inhibits activity of the DNA sensor cGAS during DNA virus infection to limit interferon production A Ghosh, L Shao, P Sampath, B Zhao, NV Patel, J Zhu, B Behl, RA Parise, ... Immunity 50 (1), 51-63. e5, 2019 | 94 | 2019 |
The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming X Zhou, J Yu, X Cheng, B Zhao, GC Manyam, L Zhang, K Schluns, P Li, ... Nature immunology 20 (7), 879-889, 2019 | 75 | 2019 |
Viral DNA binding to NLRC3, an inhibitory nucleic acid sensor, unleashes STING, a cyclic dinucleotide receptor that activates type I interferon X Li, M Deng, AS Petrucelli, C Zhu, J Mo, L Zhang, JW Tam, P Ariel, ... Immunity 50 (3), 591-599. e6, 2019 | 64 | 2019 |
The malectin-like receptor-like kinase LETUM1 modulates NLR protein SUMM2 activation via MEKK2 scaffolding J Liu, Y Huang, L Kong, X Yu, B Feng, D Liu, B Zhao, GC Mendes, P Yuan, ... Nature Plants 6 (9), 1106-1115, 2020 | 42 | 2020 |
Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1 B Zhao, C Yuan, R Li, D Qu, M Huang, JCK Ngo Journal of Biological Chemistry 288 (16), 11155-11164, 2013 | 42 | 2013 |
Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation B Zhao, S Gandhi, C Yuan, Z Luo, R Li, H Gårdsvoll, V de Lorenzi, ... Journal of molecular biology 427 (6), 1389-1403, 2015 | 28 | 2015 |
Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses JH Cho, B Zhao, J Shi, N Savage, Q Shen, J Byrnes, L Yang, W Hwang, ... Proceedings of the National Academy of Sciences 117 (12), 6550-6558, 2020 | 24 | 2020 |
Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction X Xie, J Jin, L Zhu, Z Jie, Y Li, B Zhao, X Cheng, P Li, SC Sun Cell & bioscience 9 (1), 1-10, 2019 | 23 | 2019 |
Molecular mechanisms of tight binding through fuzzy interactions Q Shen, J Shi, D Zeng, B Zhao, P Li, W Hwang, JH Cho Biophysical journal 114 (6), 1313-1320, 2018 | 21 | 2018 |
The Structural Basis of IRF-3 Activation upon Phosphorylation T Jing, B Zhao, P Xu, X Gao, L Chi, H Han, B Sankaran, P Li The Journal of Immunology 205 (7), 1886-1896, 2020 | 19 | 2020 |
The molecular mechanisms underlying the hijack of host proteins by the 1918 Spanish influenza virus Q Shen, D Zeng, B Zhao, VS Bhatt, P Li, JH Cho ACS chemical biology 12 (5), 1199-1203, 2017 | 19 | 2017 |
A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility B Zhao, P Xu, L Jiang, B Paaske, T Kromann-Hansen, JK Jensen, ... PloS one 9 (12), e115872, 2014 | 19 | 2014 |
Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography B Zhao, S Gandhi, C Yuan, Z Luo, R Li, H Gårdsvoll, V de Lorenzi, ... Data in brief 5, 107-113, 2015 | 15 | 2015 |