Challenges of up-scaling lentivirus production and processing A McCarron, M Donnelley, C McIntyre, D Parsons Journal of biotechnology 240, 23-30, 2016 | 115 | 2016 |
Airway disease phenotypes in animal models of cystic fibrosis A McCarron, M Donnelley, D Parsons Respiratory research 19, 1-12, 2018 | 90 | 2018 |
Animal and cell culture models for cystic fibrosis: which model is right for your application? A McCarron, D Parsons, M Donnelley The American journal of pathology 191 (2), 228-242, 2021 | 66 | 2021 |
Large-scale production of lentiviral vectors using multilayer cell factories N Rout-Pitt, A McCarron, C McIntyre, D Parsons, M Donnelley Journal of Biological Methods 5 (2), 2018 | 39 | 2018 |
Phenotypic characterization and comparison of cystic fibrosis rat models generated using CRISPR/Cas9 gene editing A McCarron, P Cmielewski, N Reyne, C McIntyre, J Finnie, F Craig, ... The American journal of pathology 190 (5), 977-993, 2020 | 38 | 2020 |
Methods for dynamic synchrotron X-ray respiratory imaging in live animals KS Morgan, D Parsons, P Cmielewski, A McCarron, R Gradl, N Farrow, ... Journal of Synchrotron Radiation 27 (1), 164-175, 2020 | 31 | 2020 |
Transient lentiviral vector production using a packed-bed bioreactor system A McCarron, M Donnelley, C McIntyre, D Parsons Human Gene Therapy Methods 30 (3), 93-101, 2019 | 29 | 2019 |
Effective viral-mediated lung gene therapy: is airway surface preparation necessary? A McCarron, P Cmielewski, V Drysdale, D Parsons, M Donnelley Gene Therapy 30 (6), 469-477, 2023 | 15 | 2023 |
Single-dose lentiviral mediated gene therapy recovers CFTR function in cystic fibrosis knockout rats N Reyne, P Cmielewski, A McCarron, J Delhove, D Parsons, M Donnelley Frontiers in Pharmacology 12, 682299, 2021 | 13 | 2021 |
To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis N Reyne, A McCarron, P Cmielewski, D Parsons, M Donnelley Frontiers in Physiology 14, 1104856, 2023 | 10 | 2023 |
Scale-up of lentiviral vectors for gene therapy: advances and challenges A McCarron, M Donnelley, D Parsons BioInsights, 2017 | 8 | 2017 |
Essential fatty acid deficiency in cystic fibrosis disease progression: Role of genotype and sex N Shrestha, A McCarron, N Rout-Pitt, M Donnelley, DW Parsons, ... Nutrients 14 (21), 4666, 2022 | 7 | 2022 |
Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study M Gardner, A McCarron, K Morgan, D Parsons, M Donnelley Scientific Reports 9 (1), 10983, 2019 | 6 | 2019 |
The effects of conditioning and lentiviral vector pseudotype on short-and long-term airway reporter gene expression in mice C Carpentieri, N Farrow, P Cmielewski, N Rout-Pitt, A McCarron, E Knight, ... Human Gene Therapy 32 (15-16), 817-827, 2021 | 5 | 2021 |
Breaching the delivery barrier: Chemical and physical airway epithelium disruption strategies for enhancing lentiviral-mediated gene therapy A McCarron, N Farrow, P Cmielewski, E Knight, M Donnelley, D Parsons Frontiers in Pharmacology 12, 669635, 2021 | 5 | 2021 |
Towards automated in vivo tracheal mucociliary transport measurement: Detecting and tracking particle movement in synchrotron phase-contrast x-ray images M Gardner, D Parsons, K Morgan, A McCarron, P Cmielewski, R Gradl, ... Physics in Medicine & Biology 65 (14), 145012, 2020 | 5 | 2020 |
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine J Ousingsawat, R Centeio, N Reyne, A McCarron, P Cmielewski, ... Scientific Reports 14 (1), 1464, 2024 | 4 | 2024 |
Repeat or single-dose lentiviral vector administration to mouse lungs? It’s all about the timing M Donnelley, P Cmielewski, E Knight, C Carpentieri, A McCarron, ... Gene Therapy 30 (9), 698-705, 2023 | 4 | 2023 |
Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging M Donnelley, P Cmielewski, K Morgan, J Delhove, N Reyne, A McCarron, ... Scientific Reports 12 (1), 9000, 2022 | 3 | 2022 |
Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by … A McCarron, P Cmielewski, N Reyne, C McIntyre, J Finnie, F Craig, ... Elsevier, 2020 | 2 | 2020 |