关注
Jennifer R Brown
Jennifer R Brown
Professor of Medicine, Harvard Medical School
在 dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Comprehensive genomic characterization of squamous cell lung cancers
Cancer Genome Atlas Research Network
Nature 489 (7417), 519, 2012
37182012
Targeting BCL2 with venetoclax in relapsed chronic lymphocytic leukemia
AW Roberts, MS Davids, JM Pagel, BS Kahl, SD Puvvada, JF Gerecitano, ...
New England Journal of Medicine 374 (4), 311-322, 2016
20742016
Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia
JC Byrd, JR Brown, S O'Brien, JC Barrientos, NE Kay, NM Reddy, ...
New England Journal of Medicine 371 (3), 213-223, 2014
19622014
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
DA Landau, SL Carter, P Stojanov, A McKenna, K Stevenson, ...
Cell 152 (4), 714-726, 2013
16412013
SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
L Wang, MS Lawrence, Y Wan, P Stojanov, C Sougnez, K Stevenson, ...
New England Journal of Medicine 365 (26), 2497-2506, 2011
13992011
Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia
JC Byrd, B Harrington, S O’Brien, JA Jones, A Schuh, S Devereux, ...
New England Journal of Medicine 374 (4), 323-332, 2016
10352016
Ibrutinib regimens versus chemoimmunotherapy in older patients with untreated CLL
JA Woyach, AS Ruppert, NA Heerema, W Zhao, AM Booth, W Ding, ...
New England Journal of Medicine 379 (26), 2517-2528, 2018
9862018
Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease
AW Roberts, JF Seymour, JR Brown, WG Wierda, TJ Kipps, SL Khaw, ...
Journal of Clinical Oncology 30 (5), 488-496, 2012
9452012
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ...
Nature 511 (7511), 616-620, 2014
8592014
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
VDG Moore, JR Brown, M Certo, TM Love, CD Novina, A Letai
The Journal of clinical investigation 117 (1), 112-121, 2007
7522007
Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia
JR Brown, JC Byrd, SE Coutre, DM Benson, IW Flinn, ...
Blood, The Journal of the American Society of Hematology 123 (22), 3390-3397, 2014
7412014
Final analysis from RESONATE: Up to six years of follow‐up on ibrutinib in patients with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma
T Munir, JR Brown, S O'Brien, JC Barrientos, PM Barr, NM Reddy, ...
American journal of hematology 94 (12), 1353-1363, 2019
4562019
MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele …
L Xu, ZR Hunter, G Yang, Y Zhou, Y Cao, X Liu, E Morra, A Trojani, ...
Blood, The Journal of the American Society of Hematology 121 (11), 2051-2058, 2013
4502013
A defect in nurturing in mice lacking the immediate early gene fosB
JR Brown, H Ye, RT Bronson, P Dikkes, ME Greenberg
Cell 86 (2), 297-309, 1996
4431996
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
A Yoda, Y Yoda, S Chiaretti, M Bar-Natan, K Mani, SJ Rodig, N West, ...
Proceedings of the National Academy of Sciences 107 (1), 252-257, 2010
4132010
Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia
LZ Rassenti, S Jain, MJ Keating, WG Wierda, MR Grever, JC Byrd, ...
Blood, The Journal of the American Society of Hematology 112 (5), 1923-1930, 2008
4072008
Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
S O'Brien, JA Jones, SE Coutre, AR Mato, P Hillmen, C Tam, A Österborg, ...
The Lancet Oncology 17 (10), 1409-1418, 2016
4012016
Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study
AR Mato, NN Shah, W Jurczak, CY Cheah, JM Pagel, JA Woyach, ...
The Lancet 397 (10277), 892-901, 2021
3912021
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ...
Nature communications 7 (1), 11589, 2016
3872016
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia
DA Landau, K Clement, MJ Ziller, P Boyle, J Fan, H Gu, K Stevenson, ...
Cancer cell 26 (6), 813-825, 2014
3862014
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