Limitations and possibilities of small RNA digital gene expression profiling SEV Linsen, E de Wit, G Janssens, S Heater, L Chapman, RK Parkin, ... Nature methods 6 (7), 474-476, 2009 | 354 | 2009 |
Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease YJ Liu, RL McIntyre, GE Janssens, RH Houtkooper Mechanisms of ageing and development 186, 111212, 2020 | 235 | 2020 |
Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions JP De Magalhães, CE Finch, G Janssens Ageing research reviews 9 (3), 315-323, 2010 | 182 | 2010 |
Protein biogenesis machinery is a driver of replicative aging in yeast GE Janssens, AC Meinema, J Gonzalez, JC Wolters, A Schmidt, V Guryev, ... elife 4, e08527, 2015 | 176 | 2015 |
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity XX Lin, I Sen, GE Janssens, X Zhou, BR Fonslow, D Edgar, N Stroustrup, ... Nature communications 9 (1), 4400, 2018 | 136 | 2018 |
The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource T Craig, C Smelick, R Tacutu, D Wuttke, SH Wood, H Stanley, G Janssens, ... Nucleic acids research 43 (D1), D873-D878, 2015 | 101 | 2015 |
A conserved mito-cytosolic translational balance links two longevity pathways M Molenaars, GE Janssens, EG Williams, A Jongejan, J Lan, S Rabot, ... Cell metabolism 31 (3), 549-563. e7, 2020 | 100 | 2020 |
From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs RL McIntyre, EG Daniels, M Molenaars, RH Houtkooper, GE Janssens EMBO molecular medicine 11 (9), e9854, 2019 | 95 | 2019 |
Evidence for the hallmarks of human aging in replicatively aging yeast GE Janssens, LM Veenhoff Microbial Cell 3 (7), 263, 2016 | 95 | 2016 |
Disease progression in women with X-linked adrenoleukodystrophy is slow IC Huffnagel, MGW Dijkgraaf, GE Janssens, M van Weeghel, ... Orphanet Journal of Rare Diseases 14, 1-15, 2019 | 73 | 2019 |
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics IL Rempel, MM Crane, DJ Thaller, A Mishra, DPM Jansen, G Janssens, ... Elife 8, e48186, 2019 | 71 | 2019 |
Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging GE Janssens, XX Lin, L Millan-Ariño, A Kavšek, I Sen, RI Seinstra, ... Cell Reports 27 (2), 467-480. e6, 2019 | 70 | 2019 |
Identification of key pathways and metabolic fingerprints of longevity in C. elegans AW Gao, RL Smith, M Van Weeghel, R Kamble, GE Janssens, ... Experimental gerontology 113, 128-140, 2018 | 68 | 2018 |
The natural variation in lifespans of single yeast cells is related to variation in cell size, ribosomal protein, and division time GE Janssens, LM Veenhoff PloS one 11 (12), e0167394, 2016 | 65 | 2016 |
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion YJ Liu, GE Janssens, RL McIntyre, M Molenaars, R Kamble, AW Gao, ... PLoS genetics 15 (3), e1007633, 2019 | 63 | 2019 |
Integrating the hallmarks of aging throughout the tree of life: a focus on mitochondrial dysfunction S Van der Rijt, M Molenaars, RL McIntyre, GE Janssens, RH Houtkooper Frontiers in cell and developmental biology 8, 594416, 2020 | 61 | 2020 |
Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast DHEW Huberts, S Sik Lee, J Gonzalez, GE Janssens, IA Vizcarra, ... Nature protocols 8 (6), 1019-1027, 2013 | 60 | 2013 |
Healthy aging and muscle function are positively associated with NAD+ abundance in humans GE Janssens, L Grevendonk, RZ Perez, BV Schomakers, ... Nature Aging 2 (3), 254-263, 2022 | 50 | 2022 |
Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan S Leupold, G Hubmann, A Litsios, AC Meinema, V Takhaveev, ... Elife 8, e41046, 2019 | 48 | 2019 |
Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30 YJ Liu, RL McIntyre, GE Janssens, EG Williams, J Lan, M van Weeghel, ... Journal of Cell Biology 219 (6), 2020 | 46 | 2020 |