Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation T Nishimura, S Kaneko, A Kawana-Tachikawa, Y Tajima, H Goto, D Zhu, ... Cell stem cell 12 (1), 114-126, 2013 | 423 | 2013 |
Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice F Nagawa, N Kishishita, K Shimizu, S Hirose, M Miyoshi, J Nezu, ... Nature immunology 8 (2), 206-213, 2007 | 166 | 2007 |
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 165 | 2019 |
Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease MP Chao, AJ Gentles, S Chatterjee, F Lan, A Reinisch, MR Corces, ... Cell stem cell 20 (3), 329-344. e7, 2017 | 134 | 2017 |
Inhibition of apoptosis overcomes stage-related compatibility barriers to chimera formation in mouse embryos H Masaki, M Kato-Itoh, Y Takahashi, A Umino, H Sato, K Ito, A Yanagida, ... Cell Stem Cell 19 (5), 587-592, 2016 | 121 | 2016 |
A safeguard system for induced pluripotent stem cell-derived rejuvenated T cell therapy M Ando, T Nishimura, S Yamazaki, T Yamaguchi, A Kawana-Tachikawa, ... Stem cell reports 5 (4), 597-608, 2015 | 97 | 2015 |
Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients M Sakurai, H Kunimoto, N Watanabe, Y Fukuchi, S Yuasa, S Yamazaki, ... Leukemia 28 (12), 2344-2354, 2014 | 95 | 2014 |
Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards RM Martin, JL Fowler, MK Cromer, BJ Lesch, E Ponce, N Uchida, ... Nature communications 11 (1), 2713, 2020 | 84 | 2020 |
Stepwise development of hematopoietic stem cells from embryonic stem cells K Matsumoto, T Isagawa, T Nishimura, T Ogaeri, K Eto, S Miyazaki, ... PloS one 4 (3), e4820, 2009 | 67 | 2009 |
An all-recombinant protein-based culture system specifically identifies hematopoietic stem cell maintenance factors A Ieyasu, R Ishida, T Kimura, M Morita, AC Wilkinson, K Sudo, ... Stem Cell Reports 8 (3), 500-508, 2017 | 47 | 2017 |
Efficient scarless genome editing in human pluripotent stem cells K Ikeda, N Uchida, T Nishimura, J White, RM Martin, H Nakauchi, ... Nature Methods 15 (12), 1045-1047, 2018 | 36 | 2018 |
Method for reconstructing immune function using pluripotent stem cells H Nakauchi, S Kaneko, T Nishimura US Patent 9,206,394, 2015 | 35 | 2015 |
Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses LT Ang, AT Nguyen, KJ Liu, A Chen, X Xiong, M Curtis, RM Martin, ... Cell 185 (14), 2523-2541. e30, 2022 | 22 | 2022 |
Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion T Nishimura, I Hsu, DC Martinez-Krams, Y Nakauchi, R Majeti, ... Experimental hematology 80, 16-20, 2019 | 21 | 2019 |
Functional analysis of dendritic cells generated from T-iPSCs from CD4+ T cell clones of Sjögren's syndrome M Iizuka-Koga, H Asashima, M Ando, CY Lai, S Mochizuki, M Nakanishi, ... Stem Cell Reports 8 (5), 1155-1163, 2017 | 19 | 2017 |
Generation of antigen-specific T cells from human induced pluripotent stem cells T Nishimura, H Nakauchi Immunological Tolerance: Methods and Protocols, 25-40, 2019 | 15 | 2019 |
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase MC Wilkes, K Siva, J Chen, G Varetti, MY Youn, H Chae, F Ek, R Olsson, ... Nature communications 11 (1), 3344, 2020 | 13 | 2020 |
Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells T Nishimura, H Xu, M Iwasaki, D Karigane, B Saavedra, Y Takahashi, ... Gene Therapy 27 (10), 525-534, 2020 | 12 | 2020 |
Induced pluripotent stem cell-derived gamma delta CAR-T cells for cancer immunotherapy MA Wallet, T Nishimura, C Del Casale, A Lebid, B Salantes, ... Blood 138, 2771, 2021 | 11 | 2021 |
Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells S Tachikawa, T Nishimura, H Nakauchi, K Ohnuma In Vitro Cellular & Developmental Biology-Animal 53, 841-851, 2017 | 11 | 2017 |