Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism AJ Annalora, DB Goodin, WX Hong, Q Zhang, EF Johnson, CD Stout Journal of molecular biology 396 (2), 441-451, 2010 | 191 | 2010 |
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1 N Mast, AJ Annalora, DT Lodowski, K Palczewski, CD Stout, IA Pikuleva Journal of Biological Chemistry 286 (7), 5607-5613, 2011 | 145 | 2011 |
Alternative splicing in the cytochrome P450 superfamily expands protein diversity to augment gene function and redirect human drug metabolism AJ Annalora, CB Marcus, PL Iversen Drug Metabolism and Disposition 45 (4), 375-389, 2017 | 54 | 2017 |
Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity A Annalora, E Bobrovnikova-Marjon, R Serda, L Lansing, ML Chiu, ... Archives of biochemistry and biophysics 425 (2), 133-146, 2004 | 36 | 2004 |
Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: Insights into substrate specificity and membrane bound structure … AJ Annalora, E Bobrovnikov-Marjon, R Serda, A Pastuszyn, SE Graham, ... Archives of biochemistry and biophysics 460 (2), 262-273, 2007 | 31 | 2007 |
Expression, structure‐function, and molecular modeling of vitamin D P450s JL Omdahl, EV Bobrovnikova, A Annalora, P Chen, R Serda Journal of cellular biochemistry 88 (2), 356-362, 2003 | 29 | 2003 |
Metabolic stability of 3‐Epi‐1α,25‐dihydroxyvitamin D3 over 1α, 25‐dihydroxyvitamin D3: Metabolism and molecular docking studies using rat CYP24A1 SY Rhieu, AJ Annalora, G Wang, CC Flarakos, RM Gathungu, P Vouros, ... Journal of cellular biochemistry 114 (10), 2293-2305, 2013 | 28 | 2013 |
Cytochrome P450 1B1: A key regulator of ocular iron homeostasis and oxidative stress YS Song, AJ Annalora, CB Marcus, CR Jefcoate, CM Sorenson, ... Cells 11 (19), 2930, 2022 | 24 | 2022 |
A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α, 25-dihydroxyvitamin D3 SY Rhieu, AJ Annalora, RM Gathungu, P Vouros, MR Uskokovic, ... Archives of biochemistry and biophysics 509 (1), 33-43, 2011 | 19 | 2011 |
Potent Antiproliferative Effects of 25‐Hydroxy‐16‐ene‐23‐yne‐vitamin D3 That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1 SY Rhieu, AJ Annalora, E LaPorta, JE Welsh, T Itoh, K Yamamoto, ... Journal of Cellular Biochemistry 115 (8), 1392-1402, 2014 | 17 | 2014 |
Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand-independent functions AJ Annalora, M Jozic, CB Marcus, PL Iversen Toxicology and Applied Pharmacology 364, 55-67, 2019 | 16 | 2019 |
Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease KA Lidberg, AJ Annalora, M Jozic, DJ Elson, L Wang, TK Bammler, ... Scientific reports 11 (1), 4722, 2021 | 15 | 2021 |
Contribution of circulating host and microbial tryptophan metabolites toward Ah receptor activation EW Morgan, F Dong, AJ Annalora, IA Murray, T Wolfe, R Erickson, ... International Journal of Tryptophan Research 16, 11786469231182510, 2023 | 13 | 2023 |
Alternative splicing in the nuclear receptor superfamily expands gene function to refine endo-xenobiotic metabolism AJ Annalora, CB Marcus, PL Iversen Drug Metabolism and Disposition 48 (4), 272-287, 2020 | 13 | 2020 |
The novel purification and biochemical characterization of a reversible CYP24A1: adrenodoxin complex KA Hartfield, CD Stout, AJ Annalora The Journal of steroid biochemistry and molecular biology 136, 47-53, 2013 | 12 | 2013 |
Affinity labeling of rat cytochrome P450C24 (CYP24) and identification of Ser57 as an active site residue JL Omdahl, N Swamy, R Serda, A Annalora, M Berne, R Rayb The Journal of Steroid Biochemistry and Molecular Biology 89, 159-162, 2004 | 11 | 2004 |
A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing’s family of tumors AJ Annalora, S O’Neil, JD Bushman, JE Summerton, CB Marcus, ... Oncotarget 9 (55), 30568, 2018 | 7 | 2018 |
Endogenous tryptophan-derived Ah receptor ligands are dissociated from CYP1A1/1B1-dependent negative-feedback F Dong, AJ Annalora, IA Murray, Y Tian, CB Marcus, AD Patterson, ... International Journal of Tryptophan Research 16, 11786469231182508, 2023 | 6 | 2023 |
Complex chemical signals dictate Ah receptor activation through the gut-lung axis F Dong, IA Murray, A Annalora, D Coslo, D Desai, K Gowda, J Yang, ... bioRxiv, 2023.02. 22.529529, 2023 | 6 | 2023 |
Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites D Patel, IA Murray, F Dong, AJ Annalora, K Gowda, DM Coslo, ... Metabolites 13 (9), 985, 2023 | 2 | 2023 |