GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling ARB Thomsen, B Plouffe, TJ Cahill, AK Shukla, JT Tarrasch, AM Dosey, ... Cell 166 (4), 907-919, 2016 | 543 | 2016 |
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx: evidence for similarities in store-operated and calcium release-activated … HL Ong, KT Cheng, X Liu, BC Bandyopadhyay, BC Paria, J Soboloff, ... Journal of Biological Chemistry 282 (12), 9105-9116, 2007 | 452 | 2007 |
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ... Nature 535 (7612), 448-452, 2016 | 326 | 2016 |
Lipid rafts/caveolae as microdomains of calcium signaling B Pani, BB Singh Cell calcium 45 (6), 625-633, 2009 | 325 | 2009 |
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1 (−/−) mice X Liu, KT Cheng, BC Bandyopadhyay, B Pani, A Dietrich, BC Paria, ... Proceedings of the National Academy of Sciences 104 (44), 17542-17547, 2007 | 250 | 2007 |
Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE) B Pani, HL Ong, X Liu, K Rauser, IS Ambudkar, BB Singh Journal of Biological Chemistry 283 (25), 17333-17340, 2008 | 210 | 2008 |
Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 LM Luttrell, J Wang, B Plouffe, JS Smith, L Yamani, S Kaur, ... Science Signaling 11 (549), eaat7650, 2018 | 198 | 2018 |
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure X Liu, S Ahn, AW Kahsai, KC Meng, NR Latorraca, B Pani, ... Nature 548 (7668), 480-484, 2017 | 188 | 2017 |
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1 B Pani, HL Ong, SW Brazer, X Liu, K Rauser, BB Singh, IS Ambudkar Proceedings of the National Academy of Sciences 106 (47), 20087-20092, 2009 | 157 | 2009 |
Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ... Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017 | 134 | 2017 |
Up-Regulation of Transient Receptor Potential Canonical 1 (TRPC1) following Sarco(endo)plasmic Reticulum Ca2+ ATPase 2 Gene Silencing Promotes Cell … B Pani, E Cornatzer, W Cornatzer, DM Shin, MR Pittelkow, A Hovnanian, ... Molecular biology of the cell 17 (10), 4446-4458, 2006 | 97 | 2006 |
Mechanism of β2AR regulation by an intracellular positive allosteric modulator X Liu, A Masoudi, AW Kahsai, LY Huang, B Pani, DP Staus, PJ Shim, ... Science 364 (6447), 1283-1287, 2019 | 93 | 2019 |
Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor AW Kahsai, JW Wisler, J Lee, S Ahn, TJ Cahill III, SM Dennison, DP Staus, ... Nature chemical biology 12 (9), 709-716, 2016 | 78 | 2016 |
Small-molecule positive allosteric modulators of the β2-adrenoceptor isolated from DNA-encoded libraries S Ahn, B Pani, AW Kahsai, EK Olsen, G Husemoen, M Vestergaard, L Jin, ... Molecular pharmacology 94 (2), 850-861, 2018 | 73 | 2018 |
Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling DP Staus, LM Wingler, M Choi, B Pani, A Manglik, AC Kruse, RJ Lefkowitz Proceedings of the National Academy of Sciences 115 (15), 3834-3839, 2018 | 64 | 2018 |
G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor M Choi, DP Staus, LM Wingler, S Ahn, B Pani, WD Capel, RJ Lefkowitz Science signaling 11 (544), eaar7084, 2018 | 63 | 2018 |
Impairment of TRPC1–STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1 B Pani, X Liu, S Bollimuntha, KT Cheng, IR Niesman, C Zheng, VR Achen, ... Journal of cell science 126 (2), 667-675, 2013 | 59 | 2013 |
The TR (i) P to Ca2+ signaling just got STIMy: an update on STIM1 activated TRPC channels B Pani, S Bollimuntha, BB Singh Frontiers in bioscience: a journal and virtual library 17, 805, 2012 | 51 | 2012 |
Darier’s disease: a calcium-signaling perspective B Pani, BB Singh Cellular and Molecular Life Sciences 65, 205-211, 2008 | 46 | 2008 |
Neurological and Motor Disorders: Neuronal Store-Operated Ca2+ Signaling: An Overview and Its Function S Bollimuntha, B Pani, BB Singh Store-Operated Ca²⁺ Entry (SOCE) Pathways: Emerging Signaling Concepts in …, 2017 | 36 | 2017 |