Type, density, and location of immune cells within human colorectal tumors predict clinical outcome J Galon, A Costes, F Sanchez-Cabo, A Kirilovsky, B Mlecnik, ... Science 313 (5795), 1960-1964, 2006 | 6835 | 2006 |
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks G Bindea, B Mlecnik, H Hackl, P Charoentong, M Tosolini, A Kirilovsky, ... Bioinformatics 25 (8), 1091-1093, 2009 | 5473 | 2009 |
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer G Bindea, B Mlecnik, M Tosolini, A Kirilovsky, M Waldner, AC Obenauf, ... Immunity 39 (4), 782-795, 2013 | 3065 | 2013 |
Effector memory T cells, early metastasis, and survival in colorectal cancer F Pagès, A Berger, M Camus, F Sanchez-Cabo, A Costes, R Molidor, ... New England journal of medicine 353 (25), 2654-2666, 2005 | 2452 | 2005 |
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ... The Lancet 391 (10135), 2128-2139, 2018 | 1670 | 2018 |
Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ... The Journal of pathology 232 (2), 199-209, 2014 | 1414 | 2014 |
Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer M Tosolini, A Kirilovsky, B Mlecnik, T Fredriksen, S Mauger, G Bindea, ... Cancer research 71 (4), 1263-1271, 2011 | 1262 | 2011 |
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction B Mlecnik, M Tosolini, A Kirilovsky, A Berger, G Bindea, T Meatchi, ... Journal of clinical oncology 29 (6), 610-618, 2011 | 1098 | 2011 |
In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer F Pagès, A Kirilovsky, B Mlecnik, M Asslaber, M Tosolini, G Bindea, ... Journal of clinical oncology 27 (35), 5944-5951, 2009 | 1063 | 2009 |
CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data G Bindea, J Galon, B Mlecnik Bioinformatics 29 (5), 661-663, 2013 | 990 | 2013 |
Integrative analyses of colorectal cancer show immunoscore is a stronger predictor of patient survival than microsatellite instability B Mlecnik, G Bindea, HK Angell, P Maby, M Angelova, D Tougeron, ... Immunity 44 (3), 698-711, 2016 | 934 | 2016 |
Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy M Angelova, P Charoentong, H Hackl, ML Fischer, R Snajder, ... Genome biology 16, 1-17, 2015 | 481 | 2015 |
The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis B Mlecnik, G Bindea, A Kirilovsky, HK Angell, AC Obenauf, M Tosolini, ... Science translational medicine 8 (327), 327ra26-327ra26, 2016 | 433 | 2016 |
Evolution of metastases in space and time under immune selection M Angelova, B Mlecnik, A Vasaturo, G Bindea, T Fredriksen, L Lafontaine, ... Cell 175 (3), 751-765. e16, 2018 | 356 | 2018 |
Prognostic and predictive values of the immunoscore in patients with rectal cancer MG Anitei, G Zeitoun, B Mlecnik, F Marliot, N Haicheur, AM Todosi, ... Clinical Cancer Research 20 (7), 1891-1899, 2014 | 356 | 2014 |
Characteristics and clinical impacts of the immune environments in colorectal and renal cell carcinoma lung metastases: influence of tumor origin R Remark, M Alifano, I Cremer, A Lupo, MC Dieu-Nosjean, M Riquet, ... Clinical Cancer Research 19 (15), 4079-4091, 2013 | 347 | 2013 |
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer B Mlecnik, M Tosolini, P Charoentong, A Kirilovsky, G Bindea, A Berger, ... Gastroenterology 138 (4), 1429-1440, 2010 | 324 | 2010 |
Coordination of intratumoral immune reaction and human colorectal cancer recurrence M Camus, M Tosolini, B Mlecnik, F Pages, A Kirilovsky, A Berger, ... Cancer research 69 (6), 2685-2693, 2009 | 318 | 2009 |
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases AS Berghoff, E Fuchs, G Ricken, B Mlecnik, G Bindea, T Spanberger, ... Oncoimmunology 5 (1), e1057388, 2016 | 283 | 2016 |
Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized … P Maby, D Tougeron, M Hamieh, B Mlecnik, H Kora, G Bindea, HK Angell, ... Cancer research 75 (17), 3446-3455, 2015 | 258 | 2015 |