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Joshua L Smalley
Joshua L Smalley
Research Assistant Professor, Tufts
在 tufts.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum
S Varadarajan, ETW Bampton, JL Smalley, K Tanaka, RE Caves, ...
Cell Death & Differentiation 19 (12), 1896-1907, 2012
692012
Adaptive and behavioral changes in kynurenine 3-monooxygenase knockout mice: relevance to psychotic disorders
S Erhardt, A Pocivavsek, M Repici, XC Liu, S Imbeault, DC Maddison, ...
Biological psychiatry 82 (10), 756-765, 2017
642017
Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase
L Miller-Fleming, P Antas, TF Pais, JL Smalley, F Giorgini, TF Outeiro
Proceedings of the National Academy of Sciences 111 (19), 7012-7017, 2014
612014
Application of connectivity mapping in predictive toxicology based on gene-expression similarity
JL Smalley, TW Gant, SD Zhang
Toxicology 268 (3), 143-146, 2010
612010
Locally reducing KCC2 activity in the hippocampus is sufficient to induce temporal lobe epilepsy
MR Kelley, RA Cardarelli, JL Smalley, TA Ollerhead, PM Andrew, ...
EBioMedicine 32, 62-71, 2018
582018
Neuroinflammation and ER-stress are key mechanisms of acute bilirubin toxicity and hearing loss in a mouse model
E Schiavon, JL Smalley, S Newton, NH Greig, ID Forsythe
PLoS One 13 (8), e0201022, 2018
512018
Glucose and lactate as metabolic constraints on presynaptic transmission at an excitatory synapse
SJ Lucas, CB Michel, V Marra, JL Smalley, MH Hennig, BP Graham, ...
The Journal of physiology 596 (9), 1699-1721, 2018
352018
Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis
S Varadarajan, K Tanaka, JL Smalley, ETW Bampton, M Pellecchia, ...
PLoS One 8 (2), e56603, 2013
342013
Isolation and characterization of multi-protein complexes enriched in the K-Cl Co-transporter 2 from brain plasma membranes
JL Smalley, G Kontou, C Choi, Q Ren, D Albrecht, K Abiraman, ...
Frontiers in Molecular Neuroscience 13, 563091, 2020
252020
Identification of a core amino acid motif within the α subunit of GABAARs that promotes inhibitory synaptogenesis and resilience to seizures
AJ Nathanson, Y Zhang, JL Smalley, TA Ollerhead, MAR Santos, ...
Cell reports 28 (3), 670-681. e8, 2019
232019
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice
R Jarvis, SFJ Ng, AJ Nathanson, RA Cardarelli, K Abiraman, F Wade, ...
Cell Reports Medicine 4 (3), 2023
212023
The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration
S Varadarajan, C Breda, JL Smalley, M Butterworth, SN Farrow, F Giorgini, ...
Cell Death & Differentiation 22 (8), 1388-1396, 2015
212015
KCC2 is required for the survival of mature neurons but not for their development
G Kontou, SFJ Ng, RA Cardarelli, JH Howden, C Choi, Q Ren, ...
Journal of Biological Chemistry 296, 2021
192021
Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models
JL Smalley, C Breda, RP Mason, G Kooner, R Luthi-Carter, TW Gant, ...
Journal of Molecular Medicine 94, 235-245, 2016
192016
Nanoengineered disruption of heat shock protein 90 targets drug-induced resistance and relieves natural killer cell suppression in breast cancer
M Smalley, SK Natarajan, J Mondal, D Best, D Goldman, B Shanthappa, ...
Cancer research 80 (23), 5355-5366, 2020
152020
Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes
N Madjroh, PA Davies, JL Smalley, U Kristiansen, PC Söderhielm, ...
Pharmacological research 169, 105653, 2021
72021
The K-Cl co-transporter 2 is a point of convergence for multiple autism spectrum disorder and epilepsy risk gene products
JL Smalley, G Kontou, C Choi, Q Ren, D Albrecht, K Abiraman, ...
bioRxiv, 2020.03. 02.973859, 2020
52020
Analyzing the mechanisms that facilitate the subtype-specific assembly of γ-aminobutyric acid type A receptors
C Choi, JL Smalley, AHS Lemons, Q Ren, CE Bope, JS Dengler, ...
Frontiers in Molecular Neuroscience 15, 1017404, 2022
42022
A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety
A Goldman, JL Smalley, M Mistry, H Krenzlin, H Zhang, A Dhawan, ...
Translational Psychiatry 9 (1), 336, 2019
42019
Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses
JL Smalley, N Cho, SFJ Ng, C Choi, AHS Lemons, S Chaudry, CE Bope, ...
Communications Biology 6 (1), 11, 2023
32023
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