p38 Mitogen-activated protein kinase stabilizes SMN mRNA through RNA binding protein HuR F Farooq, S Balabanian, X Liu, M Holcik, A MacKenzie Human molecular genetics 18 (21), 4035-4045, 2009 | 111 | 2009 |
Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway F Farooq, FA Molina, J Hadwen, D MacKenzie, L Witherspoon, M Osmond, ... The Journal of clinical investigation 121 (8), 3042-3050, 2011 | 104 | 2011 |
Celecoxib increases SMN and survival in a severe spinal muscular atrophy mouse model via p38 pathway activation F Farooq, F Abadía-Molina, D MacKenzie, J Hadwen, F Shamim, ... Human molecular genetics 22 (17), 3415-3424, 2013 | 67 | 2013 |
Spinal muscular atrophy: classification, diagnosis, background, molecular mechanism and development of therapeutics FT Farooq, M Holcik, A MacKenzie Neurodegenerative diseases, 2013 | 21 | 2013 |
Sodium channel inhibitors reduce DMPK mRNA and protein L Witherspoon, S O'Reilly, J Hadwen, N Tasnim, A MacKenzie, F Farooq Clinical and translational science 8 (4), 298-304, 2015 | 19 | 2015 |
Repositioning Clinic-Ready Compounds for the Treatment of Spinal Muscular Atrophy F Farooq Drug repositioning: approaches and applications for neurotherapeutics by …, 2017 | 17* | 2017 |
VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models J Hadwen, D MacKenzie, F Shamim, K Mongeon, M Holcik, A MacKenzie, ... Orphanet Journal of Rare Diseases 9, 1-9, 2014 | 17 | 2014 |
Anisomycin activates utrophin upregulation through a p38 signaling pathway J Hadwen, F Farooq, L Witherspoon, S Schock, K Mongeon, A MacKenzie Clinical and Translational Science 11 (5), 506-512, 2018 | 10 | 2018 |
Human growth hormone increases SMN expression and survival in severe spinal muscular atrophy mouse model D MacKenzie, F Shamim, K Mongeon, A Trivedi, A MacKenzie, F Farooq Journal of Neuromuscular Diseases 1 (1), 65-74, 2014 | 9 | 2014 |
Current and emerging treatment options for spinal muscular atrophy F Farooq, MK Alex Degenerative Neurological and Neuromuscular Disease 5, 75-81, 2015 | 4 | 2015 |
High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1) N Neault, S O’Reilly, AT Baig, J Plaza-Diaz, M Azimi, F Farooq, SD Baird, ... Plos one 16 (9), e0256276, 2021 | 3 | 2021 |
Separating the wheat from the chaff: the use of upstream regulator analysis to identify true differential expression of single genes within transcriptomic datasets J Hadwen, S Schock, F Farooq, A MacKenzie, J Plaza-Diaz International Journal of Molecular Sciences 22 (12), 6295, 2021 | 1 | 2021 |
Preclinical assessment of clinic ready compounds for the treatment of Spinal Muscular Atrophy. F Farooq International Conference - Educational Neuroscience, Abu Dhabi, United Arab …, 2016 | 1 | 2016 |
Re-positioning clinic ready compounds for the treatment of rare genetic diseases. F Farooq . Middle East Molecular Biology Society 2nd Annual Conference., 27, 2016 | 1 | 2016 |
Role of p38 and STAT5 Kinase pathways in the regulation of Survival of Motor Neuron gene expression for development of novel Spinal Muscular Atrophy therapeutics FT Farooq Université d'Ottawa/University of Ottawa, 2012 | 1 | 2012 |
Mapping Levels of Neurotransmitters in Different Brain Regions after Seizures under Heat Stress SMHM Fahim MA, Farooq FT, Habak C 2nd International Conference on Educational Neuroscience., 2017 | | 2017 |
Re-innervation of Learning with Neuronal Plasticity: the Neuromuscular Junction as a Model FFMB Mohamed A. Fahim, Claudine Habak, Mohamed L. Seghier International Conference - Educational Neuroscience, Abu Dhabi, United Arab …, 2016 | | 2016 |
Targeting Signal Transducer and Activator of Transcription 5 Pathway for the Treatment of Autosomal Recessive Proximal Spinal Muscular Atrophy F Farooq, A MacKenzie 3rd Middle East Molecular Biology Congress and Exhibition 2016 - Doha. Doha …, 2016 | | 2016 |
TP 8 Induction of SMN protein by combination of STAT5 and p38 kinase activating, clinic ready compounds for the treatment of SMA FT Farooq, D MacKenzie, F Shamim, M Holcik, A MacKenzie Neuromuscular Disorders 22 (9), 848-849, 2012 | | 2012 |