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Faraz Farooq
Faraz Farooq
Children's Hospital of Eastern Ontario Research Institute, University of Ottawa
在 arc.cheo.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
p38 Mitogen-activated protein kinase stabilizes SMN mRNA through RNA binding protein HuR
F Farooq, S Balabanian, X Liu, M Holcik, A MacKenzie
Human molecular genetics 18 (21), 4035-4045, 2009
1112009
Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway
F Farooq, FA Molina, J Hadwen, D MacKenzie, L Witherspoon, M Osmond, ...
The Journal of clinical investigation 121 (8), 3042-3050, 2011
1042011
Celecoxib increases SMN and survival in a severe spinal muscular atrophy mouse model via p38 pathway activation
F Farooq, F Abadía-Molina, D MacKenzie, J Hadwen, F Shamim, ...
Human molecular genetics 22 (17), 3415-3424, 2013
672013
Spinal muscular atrophy: classification, diagnosis, background, molecular mechanism and development of therapeutics
FT Farooq, M Holcik, A MacKenzie
Neurodegenerative diseases, 2013
212013
Sodium channel inhibitors reduce DMPK mRNA and protein
L Witherspoon, S O'Reilly, J Hadwen, N Tasnim, A MacKenzie, F Farooq
Clinical and translational science 8 (4), 298-304, 2015
192015
Repositioning Clinic-Ready Compounds for the Treatment of Spinal Muscular Atrophy
F Farooq
Drug repositioning: approaches and applications for neurotherapeutics by …, 2017
17*2017
VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models
J Hadwen, D MacKenzie, F Shamim, K Mongeon, M Holcik, A MacKenzie, ...
Orphanet Journal of Rare Diseases 9, 1-9, 2014
172014
Anisomycin activates utrophin upregulation through a p38 signaling pathway
J Hadwen, F Farooq, L Witherspoon, S Schock, K Mongeon, A MacKenzie
Clinical and Translational Science 11 (5), 506-512, 2018
102018
Human growth hormone increases SMN expression and survival in severe spinal muscular atrophy mouse model
D MacKenzie, F Shamim, K Mongeon, A Trivedi, A MacKenzie, F Farooq
Journal of Neuromuscular Diseases 1 (1), 65-74, 2014
92014
Current and emerging treatment options for spinal muscular atrophy
F Farooq, MK Alex
Degenerative Neurological and Neuromuscular Disease 5, 75-81, 2015
42015
High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1)
N Neault, S O’Reilly, AT Baig, J Plaza-Diaz, M Azimi, F Farooq, SD Baird, ...
Plos one 16 (9), e0256276, 2021
32021
Separating the wheat from the chaff: the use of upstream regulator analysis to identify true differential expression of single genes within transcriptomic datasets
J Hadwen, S Schock, F Farooq, A MacKenzie, J Plaza-Diaz
International Journal of Molecular Sciences 22 (12), 6295, 2021
12021
Preclinical assessment of clinic ready compounds for the treatment of Spinal Muscular Atrophy.
F Farooq
International Conference - Educational Neuroscience, Abu Dhabi, United Arab …, 2016
12016
Re-positioning clinic ready compounds for the treatment of rare genetic diseases.
F Farooq
. Middle East Molecular Biology Society 2nd Annual Conference., 27, 2016
12016
Role of p38 and STAT5 Kinase pathways in the regulation of Survival of Motor Neuron gene expression for development of novel Spinal Muscular Atrophy therapeutics
FT Farooq
Université d'Ottawa/University of Ottawa, 2012
12012
Mapping Levels of Neurotransmitters in Different Brain Regions after Seizures under Heat Stress
SMHM Fahim MA, Farooq FT, Habak C
2nd International Conference on Educational Neuroscience., 2017
2017
Re-innervation of Learning with Neuronal Plasticity: the Neuromuscular Junction as a Model
FFMB Mohamed A. Fahim, Claudine Habak, Mohamed L. Seghier
International Conference - Educational Neuroscience, Abu Dhabi, United Arab …, 2016
2016
Targeting Signal Transducer and Activator of Transcription 5 Pathway for the Treatment of Autosomal Recessive Proximal Spinal Muscular Atrophy
F Farooq, A MacKenzie
3rd Middle East Molecular Biology Congress and Exhibition 2016 - Doha. Doha …, 2016
2016
TP 8 Induction of SMN protein by combination of STAT5 and p38 kinase activating, clinic ready compounds for the treatment of SMA
FT Farooq, D MacKenzie, F Shamim, M Holcik, A MacKenzie
Neuromuscular Disorders 22 (9), 848-849, 2012
2012
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