A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease Statistical genetics and bioinformatics Goel Anuj 1 2 Ongen Halit 1 2 ... Nature genetics 43 (4), 339-344, 2011 | 691 | 2011 |
Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways N Soranzo, S Sanna, E Wheeler, C Gieger, D Radke, J Dupuis, ... Diabetes 59 (12), 3229-3239, 2010 | 484 | 2010 |
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ... Diabetes 60 (10), 2624-2634, 2011 | 458 | 2011 |
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome … NL Smith, MH Chen, A Dehghan, DP Strachan, S Basu, N Soranzo, ... Circulation 121 (12), 1382-1392, 2010 | 408 | 2010 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 396 | 2020 |
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis DI Chasman, G Pare, S Mora, JC Hopewell, G Peloso, R Clarke, ... PLoS genetics 5 (11), e1000730, 2009 | 389 | 2009 |
Association of 5′ estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk JBJ van Meurs, SCE Schuit, AEAM Weel, M van der Klift, AP Bergink, ... Human Molecular Genetics 12 (14), 1745-1754, 2003 | 254 | 2003 |
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease L Folkersen, E Fauman, M Sabater-Lleal, RJ Strawbridge, M Frånberg, ... PLoS genetics 13 (4), e1006706, 2017 | 247 | 2017 |
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease JBJ Van Meurs, G Pare, SM Schwartz, A Hazra, T Tanaka, SH Vermeulen, ... The American journal of clinical nutrition 98 (3), 668-676, 2013 | 236 | 2013 |
Circulating proprotein convertase subtilisin/kexin type 9 (PCSK9) predicts future risk of cardiovascular events independently of established risk factors K Leander, A Mälarstig, FM van’t Hooft, C Hyde, ML Hellénius, JS Troutt, ... Circulation 133 (13), 1230-1239, 2016 | 221* | 2016 |
Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants L Folkersen, T Kyriakou, A Goel, J Peden, A Mälarstig, G Paulsson-Berne, ... PloS one 4 (11), e7677, 2009 | 209 | 2009 |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease Ibc 50k Cad Consortium PLoS genetics 7 (9), e1002260, 2011 | 198 | 2011 |
Multiethnic meta-analysis of genome-wide association studies in> 100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association … M Sabater-Lleal, J Huang, D Chasman, S Naitza, A Dehghan, ... Circulation 128 (12), 1310-1324, 2013 | 161 | 2013 |
Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome A Mälarstig, P Eriksson, A Hamsten, B Lindahl, L Wallentin, A Siegbahn Heart 94 (6), 724-729, 2008 | 159 | 2008 |
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis DA Hinds, A Buil, D Ziemek, A Martinez-Perez, R Malik, L Folkersen, ... Human molecular genetics 25 (9), 1867-1874, 2016 | 137 | 2016 |
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women’s Genome Health … G Paré, DI Chasman, AN Parker, RRY Zee, A Mälarstig, U Seedorf, ... Circulation: Cardiovascular Genetics 2 (2), 142-150, 2009 | 132 | 2009 |
Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning ÅK Hedman, C Hage, A Sharma, MJ Brosnan, L Buckbinder, LM Gan, ... Heart 106 (5), 342-349, 2020 | 114 | 2020 |
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets JH Zhao, D Stacey, N Eriksson, E Macdonald-Dunlop, ÅK Hedman, ... Nature immunology 24 (9), 1540-1551, 2023 | 105 | 2023 |
Soluble CD40L levels are regulated by the− 3459 A> G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute … A Mälarstig, B Lindahl, L Wallentin, A Siegbahn Arteriosclerosis, Thrombosis, and Vascular Biology 26 (7), 1667-1673, 2006 | 99 | 2006 |
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE JK Sandling, S Garnier, S Sigurdsson, C Wang, G Nordmark, ... European Journal of Human Genetics 19 (4), 479-484, 2011 | 85 | 2011 |