| Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier B Mänz, M Schwemmle, L Brunotte Journal of virology 87 (13), 7200-7209, 2013 | 251 | 2013 |
| Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I M Weber, H Sediri, U Felgenhauer, I Binzen, S Bänfer, R Jacob, ... Cell host & microbe 17 (3), 309-319, 2015 | 170 | 2015 |
| Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells B Mänz, L Brunotte, P Reuther, M Schwemmle Nature communications 3 (1), 802, 2012 | 169 | 2012 |
| Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine S Schloer, L Brunotte, J Goretzko, A Mecate-Zambrano, N Korthals, ... Emerging microbes & infections 9 (1), 2245-2255, 2020 | 161 | 2020 |
| A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape P Hubel, C Urban, V Bergant, WM Schneider, B Knauer, A Stukalov, ... Nature immunology 20 (4), 493-502, 2019 | 156 | 2019 |
| The nuclear export protein of H5N1 influenza A viruses recruits Matrix 1 (M1) protein to the viral ribonucleoprotein to mediate nuclear export L Brunotte, J Flies, H Bolte, P Reuther, F Vreede, M Schwemmle Journal of Biological Chemistry 289 (29), 20067-20077, 2014 | 103 | 2014 |
| Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS‐CoV‐2 infection in vitro S Schloer, L Brunotte, A Mecate‐Zambrano, S Zheng, J Tang, S Ludwig, ... British journal of pharmacology 178 (11), 2339-2350, 2021 | 93 | 2021 |
| SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ... Nature communications 12 (1), 1577, 2021 | 85 | 2021 |
| Phosphorylation of TRIM28 enhances the expression of IFN-β and proinflammatory cytokines during HPAIV infection of human lung epithelial cells T Krischuns, F Günl, L Henschel, M Binder, J Willemsen, S Schloer, ... Frontiers in immunology 9, 2229, 2018 | 78 | 2018 |
| An N-terminal region of Lassa virus L protein plays a critical role in transcription but not replication of the virus genome M Lelke, L Brunotte, C Busch, S Günther Journal of virology 84 (4), 1934-1944, 2010 | 74 | 2010 |
| Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy L Brunotte, R Kerber, W Shang, F Hauer, M Hass, M Gabriel, M Lelke, ... Journal of Biological Chemistry 286 (44), 38748-38756, 2011 | 63 | 2011 |
| The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model S Schloer, N Hübel, D Masemann, D Pajonczyk, L Brunotte, C Ehrhardt, ... The FASEB Journal 33 (11), 12188, 2019 | 53 | 2019 |
| Domain structure of Lassa virus L protein L Brunotte, M Lelke, M Hass, K Kleinsteuber, B Becker-Ziaja, S Günther Journal of virology 85 (1), 324-333, 2011 | 50 | 2011 |
| The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses A Schreiber, D Viemann, J Schöning, S Schloer, A Mecate Zambrano, ... Cellular and Molecular Life Sciences 79 (1), 65, 2022 | 46 | 2022 |
| The clinically licensed antifungal drug itraconazole inhibits influenza virus in vitro and in vivo S Schloer, J Goretzko, A Kühnl, L Brunotte, S Ludwig, U Rescher Emerging microbes & infections 8 (1), 80-93, 2019 | 44 | 2019 |
| Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection J Schuhenn, TL Meister, D Todt, T Bracht, K Schork, JN Billaud, C Elsner, ... Proceedings of the National Academy of Sciences 119 (8), e2111600119, 2022 | 42 | 2022 |
| Rapid SARS-CoV-2 adaptation to available cellular proteases MZ Chaudhry, K Eschke, M Hoffmann, M Grashoff, L Abassi, Y Kim, ... Journal of Virology 96 (5), e02186-21, 2022 | 41 | 2022 |
| Adaptive mutations in the nuclear export protein of human-derived H5N1 strains facilitate a polymerase activity-enhancing conformation P Reuther, S Giese, V Götz, N Kilb, B Mänz, L Brunotte, M Schwemmle Journal of virology 88 (1), 263-271, 2014 | 41 | 2014 |
| Combination therapy with fluoxetine and the nucleoside analog GS-441524 exerts synergistic antiviral effects against different SARS-CoV-2 variants in vitro L Brunotte, S Zheng, A Mecate-Zambrano, J Tang, S Ludwig, U Rescher, ... Pharmaceutics 13 (9), 1400, 2021 | 39 | 2021 |
| Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages K Hönzke, B Obermayer, C Mache, D Fatykhova, M Kessler, S Dökel, ... European Respiratory Journal 60 (6), 2022 | 38 | 2022 |
