Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications J Zielonka, J Joseph, A Sikora, M Hardy, O Ouari, J Vasquez-Vivar, ... Chemical reviews 117 (15), 10043-10120, 2017 | 1246 | 2017 |
Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides J Zielonka, A Sikora, M Hardy, J Joseph, BP Dranka, B Kalyanaraman Chemical research in toxicology 25 (9), 1793-1799, 2012 | 250 | 2012 |
Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies B Kalyanaraman, G Cheng, M Hardy, O Ouari, B Bennett, J Zielonka Redox biology 15, 347-362, 2018 | 210 | 2018 |
A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic … B Kalyanaraman, G Cheng, M Hardy, O Ouari, M Lopez, J Joseph, ... Redox biology 14, 316-327, 2018 | 210 | 2018 |
Global profiling of reactive oxygen and nitrogen species in biological systems J Zielonka, M Zielonka, A Sikora, J Adamus, J Joseph, M Hardy, O Ouari, ... Journal of Biological Chemistry 287 (5), 2984-2995, 2012 | 197 | 2012 |
Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells G Cheng, J Zielonka, O Ouari, M Lopez, D McAllister, K Boyle, CS Barrios, ... Cancer research 76 (13), 3904-3915, 2016 | 193 | 2016 |
HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements J Zielonka, M Hardy, B Kalyanaraman Free Radical Biology and Medicine 46 (3), 329-338, 2009 | 173 | 2009 |
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis G Cheng, Q Zhang, J Pan, Y Lee, O Ouari, M Hardy, M Zielonka, ... Nature communications 10 (1), 2205, 2019 | 170 | 2019 |
HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes—the ultimate approach for intra-and extracellular superoxide detection B Kalyanaraman, BP Dranka, M Hardy, R Michalski, J Zielonka Biochimica Et Biophysica Acta (BBA)-General Subjects 1840 (2), 739-744, 2014 | 138 | 2014 |
Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo-and heterodimers J Zielonka, S Srinivasan, M Hardy, O Ouari, M Lopez, J Vasquez-Vivar, ... Free Radical Biology and Medicine 44 (5), 835-846, 2008 | 128 | 2008 |
Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling B Kalyanaraman, M Hardy, R Podsiadly, G Cheng, J Zielonka Archives of biochemistry and biophysics 617, 38-47, 2017 | 125 | 2017 |
Comprehensive Synthesis of Monohydroxy–Cucurbit[n]urils (n = 5, 6, 7, 8): High Purity and High Conversions MM Ayhan, H Karoui, M Hardy, A Rockenbauer, L Charles, R Rosas, ... Journal of the American Chemical Society 137 (32), 10238-10245, 2015 | 124 | 2015 |
Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future G Cheng, M Zielonka, B Dranka, SN Kumar, CR Myers, B Bennett, ... Journal of Biological Chemistry 293 (26), 10363-10380, 2018 | 101 | 2018 |
Detection and characterization of reactive oxygen and nitrogen species in biological systems by monitoring species-specific products M Hardy, J Zielonka, H Karoui, A Sikora, R Michalski, R Podsiadły, ... Antioxidants & redox signaling 28 (15), 1416-1432, 2018 | 92 | 2018 |
Detection of superoxide production in stimulated and unstimulated living cells using new cyclic nitrone spin traps K Abbas, M Hardy, F Poulhès, H Karoui, P Tordo, O Ouari, F Peyrot Free Radical Biology and Medicine 71, 281-290, 2014 | 90 | 2014 |
Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism G Cheng, J Zielonka, D McAllister, M Hardy, O Ouari, J Joseph, ... Cancer letters 365 (1), 96-106, 2015 | 82 | 2015 |
Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap M Hardy, A Rockenbauer, J Vásquez-Vivar, C Felix, M Lopez, ... Chemical research in toxicology 20 (7), 1053-1060, 2007 | 78 | 2007 |
Mitigation of NADPH oxidase 2 activity as a strategy to inhibit peroxynitrite formation J Zielonka, M Zielonka, L VerPlank, G Cheng, M Hardy, O Ouari, ... Journal of Biological Chemistry 291 (13), 7029-7044, 2016 | 65 | 2016 |
Toward selective detection of reactive oxygen and nitrogen species with the use of fluorogenic probes—Limitations, progress, and perspectives K Debowska, D Debski, M Hardy, M Jakubowska, B Kalyanaraman, ... Pharmacological Reports 67, 756-764, 2015 | 61 | 2015 |
Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide R Michalski, J Zielonka, M Hardy, J Joseph, B Kalyanaraman Free Radical Biology and Medicine 54, 135-147, 2013 | 53 | 2013 |