关注
Joshua Levitz
Joshua Levitz
Associate Professor, Weill Cornell Medicine
在 med.cornell.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Glutamatergic signaling in the central nervous system: ionotropic and metabotropic receptors in concert
A Reiner, J Levitz
Neuron 98 (6), 1080-1098, 2018
5662018
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme
LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ...
Cell 146 (5), 732-745, 2011
2832011
Optical control of metabotropic glutamate receptors
J Levitz, C Pantoja, B Gaub, H Janovjak, A Reiner, A Hoagland, ...
Nature neuroscience 16 (4), 507-516, 2013
2342013
Conformational dynamics of a class C G-protein-coupled receptor
R Vafabakhsh, J Levitz, EY Isacoff
Nature 524 (7566), 497-501, 2015
1852015
Mechanism of assembly and cooperativity of homomeric and heteromeric metabotropic glutamate receptors
J Levitz, C Habrian, S Bharill, Z Fu, R Vafabakhsh, EY Isacoff
Neuron 92 (1), 143-159, 2016
1702016
Restoration of high-sensitivity and adapting vision with a cone opsin
MH Berry, A Holt, A Salari, J Veit, M Visel, J Levitz, K Aghi, BM Gaub, ...
Nature communications 10 (1), 1221, 2019
1312019
Migraine-associated TRESK mutations increase neuronal excitability through alternative translation initiation and inhibition of TREK
P Royal, A Andres-Bilbe, PÁ Prado, C Verkest, B Wdziekonski, S Schaub, ...
Neuron 101 (2), 232-245. e6, 2019
1252019
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand
J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ...
ACS central science 1 (7), 383-393, 2015
1212015
Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABAB signaling
G Sandoz, J Levitz, RH Kramer, EY Isacoff
Neuron 74 (6), 1005-1014, 2012
1172012
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics
EC Carroll, S Berlin, J Levitz, MA Kienzler, Z Yuan, D Madsen, DS Larsen, ...
Proceedings of the National Academy of Sciences 112 (7), E776-E785, 2015
1002015
Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels
J Levitz, P Royal, Y Comoglio, B Wdziekonski, S Schaub, DM Clemens, ...
Proceedings of the National Academy of Sciences 113 (15), 4194-4199, 2016
892016
Structural basis for KCTD-mediated rapid desensitization of GABAB signalling
S Zheng, N Abreu, J Levitz, AC Kruse
Nature 567 (7746), 127-131, 2019
832019
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor
MH Berry, A Holt, J Levitz, J Broichhagen, BM Gaub, M Visel, C Stanley, ...
Nature communications 8 (1), 1862, 2017
832017
Optical control of dopamine receptors using a photoswitchable tethered inverse agonist
PC Donthamsetti, N Winter, M Schönberger, J Levitz, C Stanley, ...
Journal of the American Chemical Society 139 (51), 18522-18535, 2017
772017
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors
J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff
Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017
762017
Structural and biophysical mechanisms of class CG protein-coupled receptor function
A Ellaithy, J Gonzalez-Maeso, DA Logothetis, J Levitz
Trends in biochemical sciences 45 (12), 1049-1064, 2020
732020
Defining the homo-and heterodimerization propensities of metabotropic glutamate receptors
J Lee, H Munguba, VA Gutzeit, DR Singh, M Kristt, JS Dittman, J Levitz
Cell reports 31 (5), 2020
642020
Genetically targeted optical control of an endogenous G protein-coupled receptor
PC Donthamsetti, J Broichhagen, V Vyklicky, C Stanley, Z Fu, M Visel, ...
Journal of the American Chemical Society 141 (29), 11522-11530, 2019
642019
Conformational pathway provides unique sensitivity to a synaptic mGluR
CH Habrian, J Levitz, V Vyklicky, Z Fu, A Hoagland, I McCort-Tranchepain, ...
Nature communications 10 (1), 5572, 2019
632019
Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo
A Acosta-Ruiz, VA Gutzeit, MJ Skelly, S Meadows, J Lee, P Parekh, ...
Neuron 105 (3), 446-463. e13, 2020
622020
系统目前无法执行此操作,请稍后再试。
文章 1–20