Glutamatergic signaling in the central nervous system: ionotropic and metabotropic receptors in concert A Reiner, J Levitz Neuron 98 (6), 1080-1098, 2018 | 566 | 2018 |
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ... Cell 146 (5), 732-745, 2011 | 283 | 2011 |
Optical control of metabotropic glutamate receptors J Levitz, C Pantoja, B Gaub, H Janovjak, A Reiner, A Hoagland, ... Nature neuroscience 16 (4), 507-516, 2013 | 234 | 2013 |
Conformational dynamics of a class C G-protein-coupled receptor R Vafabakhsh, J Levitz, EY Isacoff Nature 524 (7566), 497-501, 2015 | 185 | 2015 |
Mechanism of assembly and cooperativity of homomeric and heteromeric metabotropic glutamate receptors J Levitz, C Habrian, S Bharill, Z Fu, R Vafabakhsh, EY Isacoff Neuron 92 (1), 143-159, 2016 | 170 | 2016 |
Restoration of high-sensitivity and adapting vision with a cone opsin MH Berry, A Holt, A Salari, J Veit, M Visel, J Levitz, K Aghi, BM Gaub, ... Nature communications 10 (1), 1221, 2019 | 131 | 2019 |
Migraine-associated TRESK mutations increase neuronal excitability through alternative translation initiation and inhibition of TREK P Royal, A Andres-Bilbe, PÁ Prado, C Verkest, B Wdziekonski, S Schaub, ... Neuron 101 (2), 232-245. e6, 2019 | 125 | 2019 |
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ... ACS central science 1 (7), 383-393, 2015 | 121 | 2015 |
Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABAB signaling G Sandoz, J Levitz, RH Kramer, EY Isacoff Neuron 74 (6), 1005-1014, 2012 | 117 | 2012 |
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics EC Carroll, S Berlin, J Levitz, MA Kienzler, Z Yuan, D Madsen, DS Larsen, ... Proceedings of the National Academy of Sciences 112 (7), E776-E785, 2015 | 100 | 2015 |
Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels J Levitz, P Royal, Y Comoglio, B Wdziekonski, S Schaub, DM Clemens, ... Proceedings of the National Academy of Sciences 113 (15), 4194-4199, 2016 | 89 | 2016 |
Structural basis for KCTD-mediated rapid desensitization of GABAB signalling S Zheng, N Abreu, J Levitz, AC Kruse Nature 567 (7746), 127-131, 2019 | 83 | 2019 |
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor MH Berry, A Holt, J Levitz, J Broichhagen, BM Gaub, M Visel, C Stanley, ... Nature communications 8 (1), 1862, 2017 | 83 | 2017 |
Optical control of dopamine receptors using a photoswitchable tethered inverse agonist PC Donthamsetti, N Winter, M Schönberger, J Levitz, C Stanley, ... Journal of the American Chemical Society 139 (51), 18522-18535, 2017 | 77 | 2017 |
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017 | 76 | 2017 |
Structural and biophysical mechanisms of class CG protein-coupled receptor function A Ellaithy, J Gonzalez-Maeso, DA Logothetis, J Levitz Trends in biochemical sciences 45 (12), 1049-1064, 2020 | 73 | 2020 |
Defining the homo-and heterodimerization propensities of metabotropic glutamate receptors J Lee, H Munguba, VA Gutzeit, DR Singh, M Kristt, JS Dittman, J Levitz Cell reports 31 (5), 2020 | 64 | 2020 |
Genetically targeted optical control of an endogenous G protein-coupled receptor PC Donthamsetti, J Broichhagen, V Vyklicky, C Stanley, Z Fu, M Visel, ... Journal of the American Chemical Society 141 (29), 11522-11530, 2019 | 64 | 2019 |
Conformational pathway provides unique sensitivity to a synaptic mGluR CH Habrian, J Levitz, V Vyklicky, Z Fu, A Hoagland, I McCort-Tranchepain, ... Nature communications 10 (1), 5572, 2019 | 63 | 2019 |
Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo A Acosta-Ruiz, VA Gutzeit, MJ Skelly, S Meadows, J Lee, P Parekh, ... Neuron 105 (3), 446-463. e13, 2020 | 62 | 2020 |