Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions R Marullo, E Werner, N Degtyareva, B Moore, G Altavilla, SS Ramalingam, ... PloS one 8 (11), e81162, 2013 | 776 | 2013 |
Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change F Kheradmand, E Werner, P Tremble, M Symons, Z Werb Science 280 (5365), 898-902, 1998 | 465 | 1998 |
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases E Werner, Z Werb The Journal of cell biology 158 (2), 357-368, 2002 | 285 | 2002 |
MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNFα X Zhang, WL Ng, P Wang, LL Tian, E Werner, H Wang, P Doetsch, ... Cancer research 72 (18), 4707-4713, 2012 | 187 | 2012 |
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ... Cell reports 20 (8), 1921-1935, 2017 | 175 | 2017 |
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes G Salazar, B Craige, ML Styers, KA Newell-Litwa, MM Doucette, ... Molecular biology of the cell 17 (9), 4014-4026, 2006 | 146 | 2006 |
GTPases and reactive oxygen species: switches for killing and signaling E Werner Journal of cell science 117 (2), 143-153, 2004 | 140 | 2004 |
AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells G Salazar, R Love, ML Styers, E Werner, A Peden, S Rodriguez, ... Journal of Biological Chemistry 279 (24), 25430-25439, 2004 | 139 | 2004 |
The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation G Salazar, R Love, E Werner, MM Doucette, S Cheng, A Levey, ... Molecular biology of the cell 15 (2), 575-587, 2004 | 131 | 2004 |
Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton E Werner, AP Kowalczyk, V Faundez Journal of Biological Chemistry 281 (32), 23227-23236, 2006 | 123 | 2006 |
Understanding cancer development processes after HZE-particle exposure: roles of ROS, DNA damage repair and inflammation DM Sridharan, A Asaithamby, SM Bailey, SV Costes, PW Doetsch, ... Radiation research 183 (1), 1-26, 2015 | 122 | 2015 |
Axon regeneration in peripheral nerves is enhanced by proteoglycan degradation ML Groves, R McKeon, E Werner, M Nagarsheth, W Meador, AW English Experimental neurology 195 (2), 278-292, 2005 | 122 | 2005 |
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1 A Gokhale, J Larimore, E Werner, L So, A Moreno-De-Luca, ... Journal of Neuroscience 32 (11), 3697-3711, 2012 | 104 | 2012 |
HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer … R Marullo, E Werner, H Zhang, GZ Chen, DM Shin, PW Doetsch Carcinogenesis 36 (11), 1397-1406, 2015 | 98 | 2015 |
Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen SJ Wall, E Werner, Z Werb, YA DeClerck Journal of Biological Chemistry 280 (48), 40187-40194, 2005 | 76 | 2005 |
The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors HS Comstra, J McArthy, S Rudin-Rush, C Hartwig, A Gokhale, SA Zlatic, ... Elife 6, e24722, 2017 | 62 | 2017 |
Systems analysis of the 22q11. 2 microdeletion syndrome converges on a mitochondrial interactome necessary for synapse function and behavior A Gokhale, C Hartwig, AAH Freeman, JL Bassell, SA Zlatic, CS Savas, ... Journal of Neuroscience 39 (18), 3561-3581, 2019 | 53 | 2019 |
Evaluating biomarkers to model cancer risk post cosmic ray exposure DM Sridharan, A Asaithamby, SR Blattnig, SV Costes, PW Doetsch, ... Life sciences in space research 9, 19-47, 2016 | 48 | 2016 |
Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer KL Limpose, KS Trego, Z Li, SW Leung, AH Sarker, JA Shah, ... Nucleic acids research 46 (9), 4515-4532, 2018 | 47 | 2018 |
Inactivation of a common OGG1 variant by TNF-alpha in mammalian cells J Morreall, K Limpose, C Sheppard, YW Kow, E Werner, PW Doetsch DNA repair 26, 15-22, 2015 | 42 | 2015 |