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Gang Yan
Gang Yan
Peking University, University of Wisconsin-Madison, Procter & Gamble
在 Pg.com 的电子邮件经过验证
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引用次数
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年份
2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl) acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies
G Yan, L Hao, Y Niu, W Huang, W Wang, F Xu, L Liang, C Wang, H Jin, ...
European journal of medicinal chemistry 137, 462-475, 2017
342017
Divergent 2‐Chloroquinazolin‐4(3H)‐one Rearrangement: Twisted‐Cyclic Guanidine Formation or Ring‐Fused N‐Acylguanidines via a Domino Process
G Yan, BL Zekarias, X Li, VA Jaffett, IA Guzei, JE Golden
Chemistry–A European Journal 26 (11), 2486-2492, 2020
222020
4-Oxo-1, 4-dihydro-quinoline-3-carboxamides as BACE-1 inhibitors: Synthesis, biological evaluation and docking studies
P Liu, Y Niu, C Wang, Q Sun, Y Zhai, J Yu, J Sun, F Xu, G Yan, W Huang, ...
European journal of medicinal chemistry 79, 413-421, 2014
222014
A matched molecular pair (MMP) approach for selecting analogs suitable for structure activity relationship (SAR)-based read across
CC Lester, G Yan
Regulatory Toxicology and Pharmacology 124, 104966, 2021
162021
Quantifying analogue suitability for SAR-based read-across toxicological assessment
C Lester, EL Byrd, M Shobair, G Yan
Chemical Research in Toxicology 36 (2), 230-242, 2023
132023
Synthesis, bioactivity, docking and molecular dynamics studies of furan‐based peptides as 20S proteasome inhibitors
Q Sun, B Xu, Y Niu, F Xu, L Liang, C Wang, J Yu, G Yan, W Wang, H Jin, ...
ChemMedChem 10 (3), 498-510, 2015
112015
Palladium-catalyzed cyclocarbonylation of pyridinylated vinylogous amides and ureas to generate ring-fused pyridopyrimidinones
G Yan, JE Golden
Organic letters 20 (15), 4393-4396, 2018
62018
Engineering selectivity for reduced toxicity of bacterial kinase inhibitors using structure-guided medicinal chemistry
N Wlodarchak, JB Feltenberger, Z Ye, J Beczkiewicz, R Procknow, G Yan, ...
ACS Medicinal Chemistry Letters 12 (2), 228-235, 2021
52021
Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action
G Yan, J Rose, C Ellison, AM Mudd, X Zhang, S Wu
Chemical Research in Toxicology 36 (9), 1532-1548, 2023
32023
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids
S Wu, C Ellison, J Naciff, M Karb, C Obringer, G Yan, Y Shan, A Smith, ...
Toxicological Sciences 191 (2), 343-356, 2023
32023
Synthetic Method Development of Drug-like Heterocycles and Medicinal Chemistry Optimization of Anti-infective and Anti-cancer Compounds
G Yan
The University of Wisconsin-Madison, 2020
2020
Compound capable of inhibiting beta-secretase, and preparation method and application thereof.
P Xu, Y Niu, G Yan, F Xu
CN Patent CN 104,860,937 A, 2015
2015
Synthetic strategies for piperazine derivatives
Y Zhai, G Yan, W Huang, Y Niu, F Xu, L Liang, C Wang, P Xu
Journal of Chinese Pharmaceutical Sciences 23 (8), 572, 2014
2014
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