2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl) acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies G Yan, L Hao, Y Niu, W Huang, W Wang, F Xu, L Liang, C Wang, H Jin, ... European journal of medicinal chemistry 137, 462-475, 2017 | 34 | 2017 |
Divergent 2‐Chloroquinazolin‐4(3H)‐one Rearrangement: Twisted‐Cyclic Guanidine Formation or Ring‐Fused N‐Acylguanidines via a Domino Process G Yan, BL Zekarias, X Li, VA Jaffett, IA Guzei, JE Golden Chemistry–A European Journal 26 (11), 2486-2492, 2020 | 22 | 2020 |
4-Oxo-1, 4-dihydro-quinoline-3-carboxamides as BACE-1 inhibitors: Synthesis, biological evaluation and docking studies P Liu, Y Niu, C Wang, Q Sun, Y Zhai, J Yu, J Sun, F Xu, G Yan, W Huang, ... European journal of medicinal chemistry 79, 413-421, 2014 | 22 | 2014 |
A matched molecular pair (MMP) approach for selecting analogs suitable for structure activity relationship (SAR)-based read across CC Lester, G Yan Regulatory Toxicology and Pharmacology 124, 104966, 2021 | 16 | 2021 |
Quantifying analogue suitability for SAR-based read-across toxicological assessment C Lester, EL Byrd, M Shobair, G Yan Chemical Research in Toxicology 36 (2), 230-242, 2023 | 13 | 2023 |
Synthesis, bioactivity, docking and molecular dynamics studies of furan‐based peptides as 20S proteasome inhibitors Q Sun, B Xu, Y Niu, F Xu, L Liang, C Wang, J Yu, G Yan, W Wang, H Jin, ... ChemMedChem 10 (3), 498-510, 2015 | 11 | 2015 |
Palladium-catalyzed cyclocarbonylation of pyridinylated vinylogous amides and ureas to generate ring-fused pyridopyrimidinones G Yan, JE Golden Organic letters 20 (15), 4393-4396, 2018 | 6 | 2018 |
Engineering selectivity for reduced toxicity of bacterial kinase inhibitors using structure-guided medicinal chemistry N Wlodarchak, JB Feltenberger, Z Ye, J Beczkiewicz, R Procknow, G Yan, ... ACS Medicinal Chemistry Letters 12 (2), 228-235, 2021 | 5 | 2021 |
Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action G Yan, J Rose, C Ellison, AM Mudd, X Zhang, S Wu Chemical Research in Toxicology 36 (9), 1532-1548, 2023 | 3 | 2023 |
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids S Wu, C Ellison, J Naciff, M Karb, C Obringer, G Yan, Y Shan, A Smith, ... Toxicological Sciences 191 (2), 343-356, 2023 | 3 | 2023 |
Synthetic Method Development of Drug-like Heterocycles and Medicinal Chemistry Optimization of Anti-infective and Anti-cancer Compounds G Yan The University of Wisconsin-Madison, 2020 | | 2020 |
Compound capable of inhibiting beta-secretase, and preparation method and application thereof. P Xu, Y Niu, G Yan, F Xu CN Patent CN 104,860,937 A, 2015 | | 2015 |
Synthetic strategies for piperazine derivatives Y Zhai, G Yan, W Huang, Y Niu, F Xu, L Liang, C Wang, P Xu Journal of Chinese Pharmaceutical Sciences 23 (8), 572, 2014 | | 2014 |