Predictable and precise template-free CRISPR editing of pathogenic variants MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ... Nature 563 (7733), 646-651, 2018 | 525 | 2018 |
plasmidSPAdes: assembling plasmids from whole genome sequencing data PAP Dmitry Antipov, Nolan Hartwick, Max W Shen, Mikahil Raiko, Alla Lapidus Bioinformatics 32 (22), 3380-3387, 2016 | 519 | 2016 |
Continuous evolution of SpCas9 variants compatible with non-G PAMs SM Miller, T Wang, PB Randolph, M Arbab, MW Shen, TP Huang, ... Nature biotechnology 38 (4), 471-481, 2020 | 303 | 2020 |
Assembly of long error-prone reads using de Bruijn graphs Y Lin, J Yuan, M Kolmogorov, MW Shen, M Chaisson, PA Pevzner Proceedings of the National Academy of Sciences 113 (52), E8396-E8405, 2016 | 298 | 2016 |
Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis J Xiao, R Jin, X Yu, M Shen, JD Wagner, A Pai, C Song, M Zhuang, ... Nature genetics 49 (10), 1546-1552, 2017 | 227 | 2017 |
Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning Max W. Shen*, Mandana Arbab*, Beverly Mok, Christopher Wilson, Żaneta ... Cell, 2020 | 218 | 2020 |
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature biotechnology 39 (11), 1414-1425, 2021 | 156 | 2021 |
PrimeDesign software for rapid and simplified design of prime editing guide RNAs JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ... Nature Communications 12 (1), 1034, 2021 | 144 | 2021 |
MEG source imaging method using fast L1 minimum-norm and its applications to signals with brain noise and human resting-state source amplitude images MX Huang, CW Huang, A Robb, AM Angeles, SL Nichols, DG Baker, ... Neuroimage 84, 585-604, 2014 | 69 | 2014 |
Base editing rescue of spinal muscular atrophy in cells and in mice M Arbab, Z Matuszek, KM Kray, A Du, GA Newby, AJ Blatnik, A Raguram, ... Science 380 (6642), eadg6518, 2023 | 59 | 2023 |
Peptide fusion improves prime editing efficiency M Velimirovic, LC Zanetti, MW Shen, JD Fife, L Lin, M Cha, E Akinci, ... Nature Communications 13 (1), 3512, 2022 | 34 | 2022 |
Meta-analysis of point-of-care lung ultrasonography versus chest radiography in adults with symptoms of acute decompensated heart failure L Chiu, MP Jairam, R Chow, N Chiu, M Shen, A Alhassan, CH Lo, A Chen, ... The American journal of cardiology 174, 89-95, 2022 | 32 | 2022 |
Towards understanding and improving gflownet training MW Shen, E Bengio, E Hajiramezanali, A Loukas, K Cho, T Biancalani International Conference on Machine Learning, 30956-30975, 2023 | 28 | 2023 |
Trust in AI: Interpretability is not necessary or sufficient, while black-box interaction is necessary and sufficient MW Shen arXiv preprint arXiv:2202.05302, 2022 | 21 | 2022 |
Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency HC Bermudez-Cabrera, S Culbertson, S Barkal, B Holmes, MW Shen, ... Nature communications 12 (1), 5111, 2021 | 15 | 2021 |
Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression L Lin, B Holmes, MW Shen, D Kammeron, N Geijsen, DK Gifford, ... Cell Reports 33 (8), 2020 | 13 | 2020 |
Stab: Self-supervised learning for tabular data E Hajiramezanali, NL Diamant, G Scalia, MW Shen NeurIPS 2022 First Table Representation Workshop, 2022 | 12 | 2022 |
Systems and methods for predicting repair outcomes in genetic engineering MW Shen, JYT HSU, M Arbab, DK Gifford, DR Liu, RI Sherwood | 12 | 2020 |
Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction F Bossi, J Fan, J Xiao, L Chandra, M Shen, Y Dorone, D Wagner, ... BMC genomics 18, 1-20, 2017 | 11 | 2017 |
Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning JC Chen, JP Chen, MW Shen, M Wornow, M Bae, WH Yeh, A Hsu, DR Liu Nature Communications 13 (1), 4541, 2022 | 10 | 2022 |