Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS) GL Hura, AL Menon, M Hammel, RP Rambo, FL Poole Ii, SE Tsutakawa, ... Nature methods 6 (8), 606-612, 2009 | 727 | 2009 |
Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ... Cell 145 (2), 198-211, 2011 | 321 | 2011 |
Exploring the repeat protein universe through computational protein design TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ... Nature 528 (7583), 580-584, 2015 | 291 | 2015 |
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome AH Sarker, SE Tsutakawa, S Kostek, C Ng, DS Shin, M Peris, E Campeau, ... Molecular cell 20 (2), 187-198, 2005 | 277 | 2005 |
Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ... Molecular cell 64 (4), 688-703, 2016 | 247 | 2016 |
High-throughput SAXS for the characterization of biomolecules in solution: a practical approach KN Dyer, M Hammel, RP Rambo, SE Tsutakawa, I Rodic, S Classen, ... Structural genomics: General applications, 245-258, 2014 | 230 | 2014 |
Determination of in vivo phosphorylation sites in protein kinase C SE Tsutakawa, KF Medzihradszky, AJ Flint, AL Burlingame, DE Koshland Journal of Biological Chemistry 270 (45), 26807-26812, 1995 | 137 | 1995 |
Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex SE Tsutakawa, H Jingami, K Morikawa Cell 99 (6), 615-623, 1999 | 135 | 1999 |
A new structural framework for integrating replication protein A into DNA processing machinery CA Brosey, C Yan, SE Tsutakawa, WT Heller, RP Rambo, JA Tainer, ... Nucleic acids research 41 (4), 2313-2327, 2013 | 113 | 2013 |
The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once SE Tsutakawa, J Lafrance-Vanasse, JA Tainer DNA repair 19, 95-107, 2014 | 111 | 2014 |
Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability SE Tsutakawa, MJ Thompson, AS Arvai, AJ Neil, SJ Shaw, SI Algasaier, ... Nature communications 8 (1), 15855, 2017 | 105 | 2017 |
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes SE Tsutakawa, DS Shin, CD Mol, T Izumi, AS Arvai, AK Mantha, ... Journal of Biological Chemistry 288 (12), 8445-8455, 2013 | 100 | 2013 |
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography SE Tsutakawa, GL Hura, KA Frankel, PK Cooper, JA Tainer Journal of structural biology 158 (2), 214-223, 2007 | 97 | 2007 |
The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system NG Lintner, KA Frankel, SE Tsutakawa, DL Alsbury, V Copié, MJ Young, ... Journal of molecular biology 405 (4), 939-955, 2011 | 93 | 2011 |
Dissection of DNA double-strand-break repair using novel single-molecule forceps JL Wang, C Duboc, Q Wu, T Ochi, S Liang, SE Tsutakawa, SP Lees-Miller, ... Nature structural & molecular biology 25 (6), 482-487, 2018 | 85 | 2018 |
Crystallographic and functional studies of very short patch repair endonuclease SE Tsutakawa, T Muto, T Kawate, H Jingami, N Kunishima, M Ariyoshi, ... Molecular cell 3 (5), 621-628, 1999 | 81 | 1999 |
Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases JA Grasby, LD Finger, SE Tsutakawa, JM Atack, JA Tainer Trends in biochemical sciences 37 (2), 74-84, 2012 | 78 | 2012 |
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA SE Tsutakawa, AW Van Wynsberghe, BD Freudenthal, CP Weinacht, ... Proceedings of the National Academy of Sciences 108 (43), 17672-17677, 2011 | 72 | 2011 |
Transcription preinitiation complex structure and dynamics provide insight into genetic diseases C Yan, T Dodd, Y He, JA Tainer, SE Tsutakawa, I Ivanov Nature structural & molecular biology 26 (6), 397-406, 2019 | 70 | 2019 |
Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp2 K Shi, K Kurahashi, R Gao, SE Tsutakawa, JA Tainer, Y Pommier, ... Nature structural & molecular biology 19 (12), 1372-1377, 2012 | 70 | 2012 |