Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance CM Yamazaki, A Yamaguchi, Y Anami, W Xiong, Y Otani, J Lee, NT Ueno, ... Nature communications 12 (1), 3528, 2021 | 150 | 2021 |
Glioma and temozolomide induced alterations in gut microbiome A Patrizz, A Dono, S Zorofchian, G Hines, T Takayasu, N Husein, Y Otani, ... Scientific reports 10 (1), 21002, 2020 | 56 | 2020 |
Annexin A2 regulates angiogenesis and invasion phenotypes of malignant glioma M Onishi, T Ichikawa, K Kurozumi, S Inoue, T Maruo, Y Otani, K Fujii, ... Brain tumor pathology 32, 184-194, 2015 | 45 | 2015 |
Oncolytic HSV therapy increases trametinib access to brain tumors and sensitizes them in vivo JY Yoo, J Swanner, Y Otani, M Nair, F Park, Y Banasavadi-Siddegowda, ... Neuro-oncology 21 (9), 1131-1140, 2019 | 42 | 2019 |
Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration A Uneda, K Kurozumi, A Fujimura, K Fujii, J Ishida, Y Shimazu, Y Otani, ... Acta Neuropathologica Communications 9, 1-23, 2021 | 34 | 2021 |
NOTCH-induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates antitumor immunotherapy Y Otani, JY Yoo, CT Lewis, S Chao, J Swanner, T Shimizu, JM Kang, ... Clinical Cancer Research 28 (7), 1460-1473, 2022 | 33 | 2022 |
Phenotypic transition as a survival strategy of glioma T Ichikawa, Y Otani, K Kurozumi, I Date Neurologia medico-chirurgica 56 (7), 387-395, 2016 | 33 | 2016 |
Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion Y Otani, T Ichikawa, K Kurozumi, S Inoue, J Ishida, T Oka, T Shimizu, ... Oncogene 37 (6), 777-786, 2018 | 32 | 2018 |
MicroRNA-138 suppresses glioblastoma proliferation through downregulation of CD44 M Yeh, YY Wang, JY Yoo, C Oh, Y Otani, JM Kang, ES Park, E Kim, ... Scientific reports 11 (1), 9219, 2021 | 31 | 2021 |
Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition Y Otani, JY Yoo, S Chao, J Liu, AC Jaime-Ramirez, TJ Lee, B Hurwitz, ... Clinical Cancer Research 26 (10), 2381-2392, 2020 | 30 | 2020 |
Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors Y Anami, Y Otani, W Xiong, SYY Ha, A Yamaguchi, KA Rivera-Caraballo, ... Cell reports 39 (8), 2022 | 28 | 2022 |
Oncolytic herpes virus armed with vasculostatin in combination with bevacizumab abrogates glioma invasion via the CCN1 and AKT signaling pathways Y Tomita, K Kurozumi, JY Yoo, K Fujii, T Ichikawa, Y Matsumoto, A Uneda, ... Molecular cancer therapeutics 18 (8), 1418-1429, 2019 | 28 | 2019 |
Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology Research U Sahu, RF Barth, Y Otani, R McCormack, B Kaur Journal of Neuropathology & Experimental Neurology 81 (5), 312-329, 2022 | 26 | 2022 |
Inhibiting protein phosphatase 2A increases the antitumor effect of protein arginine methyltransferase 5 inhibition in models of glioblastoma Y Otani, HP Sur, G Rachaiah, S Namagiri, A Chowdhury, CT Lewis, ... Neuro-oncology 23 (9), 1481-1493, 2021 | 22 | 2021 |
Congenital glioblastoma with distinct clinical and molecular characteristics: case reports and a literature review. DI Kameda M, Otani Y, Ichikawa T, Shimada A, Ichimura K World Neurosurg, 2017 | 22 | 2017 |
A super gene expression system enhances the anti-glioma effects of adenovirus-mediated REIC/Dkk-3 gene therapy. DI Oka T, Kurozumi K, Shimazu Y, Ichikawa T, Ishida J, Otani Y, Shimizu T ... Scientific report, 2016 | 20 | 2016 |
Annexin A2–STAT3–Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma Y Matsumoto, T Ichikawa, K Kurozumi, Y Otani, A Fujimura, K Fujii, ... Acta neuropathologica communications 8, 1-13, 2020 | 19 | 2020 |
δ-catenin promotes bevacizumab-induced glioma invasion T Shimizu, J Ishida, K Kurozumi, T Ichikawa, Y Otani, T Oka, Y Tomita, ... Molecular cancer therapeutics 18 (4), 812-822, 2019 | 19 | 2019 |
Evaluation of extracellular matrix protein CCN1 as a prognostic factor for glioblastoma DI Ishida J, Kurozumi K, Ichikawa T, Otani Y, Onishi M, Fujii K, Shimazu Y ... Brain Tumor Pathol, 245-52, 2015 | 19 | 2015 |
Clinicopathological and Genetic Features of Supratentorial Cortical Ependymomas Y Matsumoto, T Ichikawa, K Kurozumi, Y Otani, I Date World neurosurgery 129, e417-e428, 2019 | 16 | 2019 |