Enantio-and diastereodivergent dual catalysis: α-allylation of branched aldehydes S Krautwald, D Sarlah, MA Schafroth, EM Carreira Science 340 (6136), 1065-1068, 2013 | 819 | 2013 |
Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis S Krautwald, MA Schafroth, D Sarlah, EM Carreira Journal of the American Chemical Society 136 (8), 3020-3023, 2014 | 375 | 2014 |
An activity-guided map of electrophile-cysteine interactions in primary human T cells EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ... Cell 182 (4), 1009-1026. e29, 2020 | 261 | 2020 |
Iridium-catalyzed enantioselective polyene cyclization MA Schafroth, D Sarlah, S Krautwald, EM Carreira Journal of the American Chemical Society 134 (50), 20276-20278, 2012 | 204 | 2012 |
Stereodivergent Total Synthesis of Δ9‐Tetrahydrocannabinols MA Schafroth, G Zuccarello, S Krautwald, D Sarlah, EM Carreira Angewandte Chemie 126 (50), 14118-14121, 2014 | 166 | 2014 |
DCAF11 supports targeted protein degradation by electrophilic proteolysis-targeting chimeras X Zhang, LM Luukkonen, CL Eissler, VM Crowley, Y Yamashita, ... Journal of the American Chemical Society 143 (13), 5141-5149, 2021 | 132 | 2021 |
Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling MV Westphal, MA Schafroth, RC Sarott, MA Imhof, CP Bold, P Leippe, ... Journal of the American Chemical Society 139 (50), 18206-18212, 2017 | 106 | 2017 |
LPCAT3 inhibitors remodel the polyunsaturated phospholipid content of human cells and protect from ferroptosis A Reed, TA Ichu, N Milosevich, B Melillo, MA Schafroth, Y Otsuka, ... ACS chemical biology 17 (6), 1607-1618, 2022 | 87 | 2022 |
Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high A Chicca, MA Schafroth, I Reynoso-Moreno, R Erni, V Petrucci, ... Science advances 4 (10), eaat2166, 2018 | 77 | 2018 |
HATRIC-based identification of receptors for orphan ligands N Sobotzki, MA Schafroth, A Rudnicka, A Koetemann, F Marty, S Goetze, ... Nature communications 9 (1), 1519, 2018 | 67 | 2018 |
Enantioselective Iridium-catalyzed allylic cyclizations MA Schafroth, SM Rummelt, D Sarlah, EM Carreira Organic letters 19 (12), 3235-3238, 2017 | 62 | 2017 |
Proteomic discovery of chemical probes that perturb protein complexes in human cells MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ... Molecular cell 83 (10), 1725-1742. e12, 2023 | 55 | 2023 |
Amine-selective bioconjugation using arene diazonium salts S Diethelm, MA Schafroth, EM Carreira Organic letters 16 (15), 3908-3911, 2014 | 55 | 2014 |
Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology MA Schafroth, G Mazzoccanti, I Reynoso-Moreno, R Erni, F Pollastro, ... Journal of natural products 84 (9), 2502-2510, 2021 | 51 | 2021 |
Positron emission tomography imaging of the endocannabinoid system: opportunities and challenges in radiotracer development L Hou, J Rong, A Haider, D Ogasawara, C Varlow, MA Schafroth, L Mu, ... Journal of medicinal chemistry 64 (1), 123-149, 2020 | 47 | 2020 |
In situ identification of cellular drug targets in mammalian tissue Z Pang, MA Schafroth, D Ogasawara, Y Wang, V Nudell, NK Lal, D Yang, ... Cell 185 (10), 1793-1805. e17, 2022 | 45 | 2022 |
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension MM Rinschen, O Palygin, A El-Meanawy, X Domingo-Almenara, ... Nature Communications 13 (1), 4099, 2022 | 44 | 2022 |
Design, synthesis, and evaluation of reversible and irreversible monoacylglycerol lipase positron emission tomography (PET) tracers using a “tail switching” strategy on a … Z Chen, W Mori, X Deng, R Cheng, D Ogasawara, G Zhang, MA Schafroth, ... Journal of medicinal chemistry 62 (7), 3336-3353, 2019 | 41 | 2019 |
Design, Synthesis, and Evaluation of 18F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes Z Chen, W Mori, H Fu, MA Schafroth, A Hatori, T Shao, G Zhang, RS Van, ... Journal of medicinal chemistry 62 (19), 8866-8872, 2019 | 26 | 2019 |
Synthesis of phytocannabinoids MA Schafroth, EM Carreira Phytocannabinoids: Unraveling the Complex Chemistry and Pharmacology of …, 2017 | 16 | 2017 |