| The energetics of hydrogen bonds in model systems: implications for enzymatic catalysis S Shan, S Loh, D Herschlag Science 272 (5258), 97-101, 1996 | 318 | 1996 |
| Structure, function, and aggregation of the zinc-free form of the p53 DNA binding domain JS Butler, SN Loh Biochemistry 42 (8), 2396-2403, 2003 | 214 | 2003 |
| Structure and stability of a second molten globule intermediate in the apomyoglobin folding pathway. SN Loh, MS Kay, RL Baldwin Proceedings of the National Academy of Sciences 92 (12), 5446-5450, 1995 | 172 | 1995 |
| Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy CA Royer, AP Hinck, SN Loh, KE Prehoda, X Peng, J Jonas, JL Markley Biochemistry 32 (19), 5222-5232, 1993 | 171 | 1993 |
| Protein conformational switches: from nature to design JH Ha, SN Loh Chemistry–A European Journal 18 (26), 7984-7999, 2012 | 153 | 2012 |
| The missing zinc: p53 misfolding and cancer SN Loh Metallomics 2 (7), 442-449, 2010 | 144 | 2010 |
| Hydrogen bonding in proteins as studied by amide hydrogen D/H fractionation factors: application to staphylococcal nuclease SN Loh, JL Markley Biochemistry 33 (4), 1029-1036, 1994 | 132 | 1994 |
| Solvent effects on the energetics of prolyl peptide bond isomerization ES Eberhardt, SN Loh, AP Hinck, RT Raines Journal of the American Chemical Society 114 (13), 5437-5439, 1992 | 129 | 1992 |
| Hydrogen exchange in unligated and ligated staphylococcal nuclease SN Loh, KE Prehoda, J Wang, JL Markley Biochemistry 32 (41), 11022-11028, 1993 | 120 | 1993 |
| Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism X Yu, AR Blanden, S Narayanan, L Jayakumar, D Lubin, D Augeri, ... Oncotarget 5 (19), 8879, 2014 | 113 | 2014 |
| EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction J Zhao, A Blayney, X Liu, L Gandy, W Jin, L Yan, JH Ha, AJ Canning, ... Nature communications 12 (1), 986, 2021 | 107 | 2021 |
| Allosteric switching by mutually exclusive folding of protein domains TL Radley, AI Markowska, BT Bettinger, JH Ha, SN Loh Journal of molecular biology 332 (3), 529-536, 2003 | 107 | 2003 |
| Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer AR Blanden, X Yu, SN Loh, AJ Levine, DR Carpizo Drug discovery today 20 (11), 1391-1397, 2015 | 95 | 2015 |
| Dynamics of equilibrium structural fluctuations of apomyoglobin measured by fluorescence correlation spectroscopy H Chen, E Rhoades, JS Butler, SN Loh, WW Webb Proceedings of the National Academy of Sciences 104 (25), 10459-10464, 2007 | 94 | 2007 |
| Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore AR Blanden, X Yu, AJ Wolfe, JA Gilleran, DJ Augeri, RS O’Dell, EC Olson, ... Molecular pharmacology 87 (5), 825-831, 2015 | 89 | 2015 |
| Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients MR Woodford, RA Sager, E Marris, DM Dunn, AR Blanden, RL Murphy, ... The EMBO journal 36 (24), 3650-3665, 2017 | 79 | 2017 |
| Changes in side chain packing during apomyoglobin folding characterized by pulsed thiol-disulfide exchange JH Ha, SN Loh nature structural biology 5 (8), 730-737, 1998 | 64 | 1998 |
| The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding MR Woodford, DM Dunn, AR Blanden, D Capriotti, D Loiselle, ... Nature communications 7 (1), 12037, 2016 | 63 | 2016 |
| Zn2+-Dependent Misfolding of the p53 DNA Binding Domain JS Butler, SN Loh Biochemistry 46 (10), 2630-2639, 2007 | 63 | 2007 |
| A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding MM Stratton, DM Mitrea, SN Loh ACS chemical biology 3 (11), 723-732, 2008 | 61 | 2008 |
