Swellable matrices for controlled drug delivery: gel-layer behaviour, mechanisms and optimal performance P Colombo, R Bettini, P Santi, NA Peppas Pharmaceutical science & technology today 3 (6), 198-204, 2000 | 618 | 2000 |
Analysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport P Colombo, R Bettini, P Santi, A De Ascentiis, NA Peppas Journal of controlled release 39 (2-3), 231-237, 1996 | 331 | 1996 |
Drug diffusion front movement is important in drug release control from swellable matrix tablets P Colombo, R Bettini, G Massimo, PL Catellani, P Santi, NA Peppas Journal of pharmaceutical sciences 84 (8), 991-997, 1995 | 321 | 1995 |
Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose (HPMC) matrices containing a soluble drug P Colombo, R Bettini, NA Peppas Journal of Controlled Release 61 (1-2), 83-91, 1999 | 296 | 1999 |
Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate R Bettini, PL Catellani, P Santi, G Massimo, NA Peppas, P Colombo Journal of Controlled Release 70 (3), 383-391, 2001 | 282 | 2001 |
Supercritical fluid technologies: an innovative approach for manipulating the solid-state of pharmaceuticals I Pasquali, R Bettini, F Giordano Advanced Drug Delivery Reviews 60 (3), 399-410, 2008 | 225 | 2008 |
Swelling and drug release in hydrogel matrices: polymer viscosity and matrix porosity effects R Bettini, P Colombo, G Massimo, PL Catellani, T Vitali European Journal of Pharmaceutical Sciences 2 (3), 213-219, 1994 | 211 | 1994 |
Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics I Pasquali, R Bettini, F Giordano European journal of pharmaceutical sciences 27 (4), 299-310, 2006 | 197 | 2006 |
Are pharmaceutics really going supercritical? I Pasquali, R Bettini International journal of pharmaceutics 364 (2), 176-187, 2008 | 192 | 2008 |
Characterization of a surface modified dry powder inhalation carrier prepared by “particle smoothing” PM Young, D Cocconi, P Colombo, R Bettini, R Price, DF Steele, ... Journal of pharmacy and pharmacology 54 (10), 1339-1344, 2002 | 175 | 2002 |
3D-printed chitosan-based scaffolds: An in vitro study of human skin cell growth and an in-vivo wound healing evaluation in experimental diabetes in rats C Intini, L Elviri, J Cabral, S Mros, C Bergonzi, A Bianchera, L Flammini, ... Carbohydrate polymers 199, 593-602, 2018 | 167 | 2018 |
Drug volume fraction profile in the gel phase and drug release kinetics in hydroxypropylmethyl cellulose matrices containing a soluble drug P Colombo, R Bettini, PL Catellani, P Santi, NA Peppas European Journal of Pharmaceutical Sciences 9 (1), 33-40, 1999 | 142 | 1999 |
Solubility effects on drug transport through pH-sensitive, swelling-controlled release systems: transport of theophylline and metoclopramide monohydrochloride R Bettini, P Colombo, NA Peppas Journal of Controlled Release 37 (1-2), 105-111, 1995 | 120 | 1995 |
Novel platforms for oral drug delivery P Colombo, F Sonvico, G Colombo, R Bettini Pharmaceutical research 26, 601-611, 2009 | 118 | 2009 |
Effect of Flow Rate on In Vitro Aerodynamic Performance of NEXThaler® in Comparison with Diskus® and Turbohaler® Dry Powder Inhalers F Buttini, G Brambilla, D Copelli, V Sisti, AG Balducci, R Bettini, I Pasquali Journal of aerosol medicine and pulmonary drug delivery 29 (2), 167-178, 2016 | 111 | 2016 |
Physical properties of parabens and their mixtures: solubility in water, thermal behavior, and crystal structures F Giordano, R Bettini, C Donini, A Gazzaniga, MR Caira, GGZ Zhang, ... Journal of pharmaceutical sciences 88 (11), 1210-1216, 1999 | 111 | 1999 |
Advances in oral controlled drug delivery: the role of drug–polymer and interpolymer non-covalent interactions S De Robertis, MC Bonferoni, L Elviri, G Sandri, C Caramella, R Bettini Expert opinion on drug delivery 12 (3), 441-453, 2015 | 105 | 2015 |
Assessment of solubility of ketoprofen and vanillic acid in supercritical CO2 under dynamic conditions A Stassi, R Bettini, A Gazzaniga, F Giordano, A Schiraldi Journal of Chemical & Engineering Data 45 (2), 161-165, 2000 | 100 | 2000 |
The surface roughness of lactose particles can be modulated by wet-smoothing using a high-shear mixer F Ferrari, D Cocconi, R Bettini, F Giordano, P Santi, M Tobyn, R Price, ... Aaps Pharmscitech 5, 69-74, 2004 | 93 | 2004 |
Drug release from swelling-controlled systems P Colombo, P Santi, R Bettini, CS Brazel, NA Peppas Handbook of pharmaceutical controlled release technology 9, 183-209, 2000 | 93 | 2000 |