miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors T Melkman‐Zehavi, R Oren, S Kredo‐Russo, T Shapira, AD Mandelbaum, ... The EMBO journal 30 (5), 835-845, 2011 | 347 | 2011 |
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ... Nature 605 (7909), 340-348, 2022 | 147 | 2022 |
p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss R Brosh, R Sarig, EB Natan, A Molchadsky, S Madar, C Bornstein, ... FEBS letters 584 (11), 2473-2477, 2010 | 49 | 2010 |
High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosis T Shapira, L Rankine-Wilson, JD Chao, V Pichler, C Rens, T Pfeifer, ... Frontiers in Microbiology 11, 553962, 2020 | 26 | 2020 |
Automated wormscan T Puckering, J Thompson, S Sathyamurthy, S Sukumar, T Shapira, ... F1000Research 6, 2017 | 26 | 2017 |
From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis LI Rankine-Wilson, T Shapira, C Sao Emani, Y Av-Gay Microbiology 167 (4), 001041, 2021 | 24 | 2021 |
DMN-Tre labeling for detection and high-content screening of compounds against intracellular mycobacteria HA Sahile, C Rens, T Shapira, RJ Andersen, Y Av-Gay ACS omega 5 (7), 3661-3669, 2020 | 21 | 2020 |
THP-1 and Dictyostelium Infection Models for Screening and Characterization of Anti-Mycobacterium abscessus Hit Compounds A Richter, T Shapira, Y Av-Gay Antimicrobial agents and chemotherapy 64 (1), 10.1128/aac. 01601-19, 2019 | 19 | 2019 |
A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice T Shapira, IA Monreal, SP Dion, M Jager, A Désilets, AD Olmstead, ... bioRxiv, 2021.05. 03.442520, 2021 | 18 | 2021 |
Photodynamic and contact killing polymeric fabric coating for bacteria and SARS-CoV-2 T Wright, M Vlok, T Shapira, AD Olmstead, F Jean, MO Wolf ACS Applied Materials & Interfaces 14 (1), 49-56, 2022 | 17 | 2022 |
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics J Pérez-Vargas, T Shapira, AD Olmstead, I Villanueva, CAH Thompson, ... Antiviral research 209, 105484, 2023 | 15 | 2023 |
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants J Pérez-Vargas, LJ Worrall, AD Olmstead, AT Ton, J Lee, I Villanueva, ... Emerging microbes & infections 12 (2), 2246594, 2023 | 7 | 2023 |
Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication T Shapira, S Vimalanathan, C Rens, V Pichler, S Peña-Díaz, G Jordana, ... Molecular Biomedicine 3 (1), 43, 2022 | 7 | 2022 |
Apoptosis assessment in high-content and high-throughput screening assays C Rens, T Shapira, S Peña-Diaz, JD Chao, T Pfeifer, Y Av-Gay Biotechniques 70 (6), 309-318, 2021 | 4 | 2021 |
The antimicrobial activity of innate host-directed therapies–a systematic review T Shapira, M Christofferson, Y Av-Gay International Journal of Antimicrobial Agents, 107138, 2024 | 3 | 2024 |
Glycogen Synthase Kinase 3 inhibition controls Mycobacterium tuberculosis Infection S Peña-Díaz, JD Chao, C Rens, H Haghdadi, X Zheng, K Flanagan, M Ko, ... iScience, 2024 | | 2024 |
Genomic DNA of clinical M. abscessus strains V Pichler, L Dalkilic, G Shoaib, T Shapira, L Rankine-Wilson, ... Methods 2024, 06-11, 2024 | | 2024 |
The diversity of clinical Mycobacterium abscessus isolates in morphology, glycopeptidolipids and infection rates in a macrophage model V Pichler, L Dalkilic, G Shoaib, T Shapira, L Rankine-Wilson, ... bioRxiv, 2024.02. 29.582856, 2024 | | 2024 |
Antiviral Agents, Uses Thereof and Methods for Their Preparation F Jean, R Andersen, D Williams, J Davies, R Long, T Shapira, ... US Patent App. 17/920,315, 2023 | | 2023 |
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics (vol 209, 105484, 2023) J Perez-Vargas, T Shapira, AD Olmstead, I Villanueva, CAH Thompson, ... ANTIVIRAL RESEARCH 213, 2023 | | 2023 |