| Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt Nature biotechnology 33 (2), 179-186, 2015 | 751 | 2015 |
| Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability FL Meng, Z Du, A Federation, J Hu, Q Wang, KR Kieffer-Kwon, ... Cell 159 (7), 1538-1548, 2014 | 265 | 2014 |
| Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing J Hu, RM Meyers, J Dong, RA Panchakshari, FW Alt, RL Frock Nature protocols 11 (5), 853-871, 2016 | 228 | 2016 |
| CRISPR/Cas9-mediated targeted chromosome elimination E Zuo, X Huo, X Yao, X Hu, Y Sun, J Yin, B He, X Wang, L Shi, J Ping, ... Genome biology 18, 1-18, 2017 | 194 | 2017 |
| The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing J Hu, L Sun, F Shen, Y Chen, Y Hua, Y Liu, M Zhang, Y Hu, Q Wang, ... Cell 149 (6), 1221-1232, 2012 | 193 | 2012 |
| Chromosomal loop domains direct the recombination of antigen receptor genes J Hu, Y Zhang, L Zhao, RL Frock, Z Du, RM Meyers, F Meng, DG Schatz, ... Cell 163 (4), 947-959, 2015 | 158 | 2015 |
| Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ... Nature 525 (7567), 134-139, 2015 | 111 | 2015 |
| Global detection of DNA repair outcomes induced by CRISPR-Cas9 M Liu, W Zhang, C Xin, J Yin, Y Shang, C Ai, J Li, F Meng, J Hu Nucleic Acids Research, 2021 | 73 | 2021 |
| Optimizing genome editing strategy by primer-extension-mediated sequencing J Yin, M Liu, Y Liu, J Wu, T Gan, W Zhang, Y Li, Y Zhou, J Hu Cell discovery 5 (1), 18, 2019 | 72 | 2019 |
| Highly sensitive and unbiased approach for elucidating antibody repertoires SG Lin, Z Ba, Z Du, Y Zhang, J Hu, FW Alt Proceedings of the National Academy of Sciences 113 (28), 7846-7851, 2016 | 62 | 2016 |
| Cas9 exo-endonuclease eliminates chromosomal translocations during genome editing J Yin, R Lu, C Xin, Y Wang, X Ling, D Li, W Zhang, M Liu, W Xie, L Kong, ... Nature communications 13 (1), 1204, 2022 | 60 | 2022 |
| Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption C Xin, J Yin, S Yuan, L Ou, M Liu, W Zhang, J Hu Nature communications 13 (1), 5623, 2022 | 57 | 2022 |
| Direct visualization of RNA-DNA primer removal from Okazaki fragments provides support for flap cleavage and exonucleolytic pathways in eukaryotic cells B Liu, J Hu, J Wang, D Kong Journal of Biological Chemistry 292 (12), 4777-4788, 2017 | 56 | 2017 |
| ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells X Liu, T Liu, Y Shang, P Dai, W Zhang, BJ Lee, M Huang, D Yang, Q Wu, ... Cell research 30 (9), 732-744, 2020 | 48 | 2020 |
| Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development L Zhao, RL Frock, Z Du, J Hu, L Chen, MS Krangel, FW Alt Journal of Experimental Medicine 213 (9), 1921-1936, 2016 | 42 | 2016 |
| Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates X Ling, L Chang, H Chen, X Gao, J Yin, Y Zuo, Y Huang, B Zhang, J Hu, ... Molecular Cell 81 (22), 4747-4756. e7, 2021 | 37 | 2021 |
| In-depth assessment of the PAM compatibility and editing activities of Cas9 variants W Zhang, J Yin, Z Zhang-Ding, C Xin, M Liu, Y Wang, C Ai, J Hu Nucleic Acids Research 49 (15), 8785-8795, 2021 | 37 | 2021 |
| The deubiquitinase USP38 promotes NHEJ repair through regulation of HDAC1 activity and regulates cancer cell response to genotoxic insults Y Yang, C Yang, T Li, S Yu, T Gan, J Hu, J Cui, X Zheng Cancer research 80 (4), 719-731, 2020 | 34 | 2020 |
| Developmental propagation of V (D) J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes J Hu, S Tepsuporn, RM Meyers, M Gostissa, FW Alt Proceedings of the National Academy of Sciences 111 (28), 10269-10274, 2014 | 34 | 2014 |
| Transcription shapes DNA replication initiation to preserve genome integrity Y Liu, C Ai, T Gan, J Wu, Y Jiang, X Liu, R Lu, N Gao, Q Li, X Ji, J Hu Genome biology 22 (1), 176, 2021 | 32 | 2021 |
Robin MeyersStanford University, Broad Institute of Harvard and MIT; Boston Children's Hospital; Harvard Medical在 stanford.edu 的电子邮件经过验证
