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Stephen G Brohawn
Stephen G Brohawn
Associate Professor, MCB & HWNI, University of California, Berkeley
在 berkeley.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel
SG Brohawn, J Del Mármol, R MacKinnon
Science 335 (6067), 436-441, 2012
4692012
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels
SG Brohawn, Z Su, R MacKinnon
Proceedings of the National Academy of Sciences 111 (9), 3614-3619, 2014
3982014
Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
SG Brohawn, EB Campbell, R MacKinnon
Nature 516 (7529), 126-130, 2014
3232014
New water-soluble phosphines as reductants of peptide and protein disulfide bonds: reactivity and membrane permeability
DJ Cline, SE Redding, SG Brohawn, JN Psathas, JP Schneider, C Thorpe
Biochemistry 43 (48), 15195-15203, 2004
2582004
Precise multimodal optical control of neural ensemble activity
AR Mardinly, IA Oldenburg, NC Pégard, S Sridharan, EH Lyall, ...
Nature neuroscience 21 (6), 881-893, 2018
2532018
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats
SG Brohawn, NC Leksa, ED Spear, KR Rajashankar, TU Schwartz
Science 322 (5906), 1369-1373, 2008
2272008
The nuclear pore complex has entered the atomic age
SG Brohawn, JR Partridge, JRR Whittle, TU Schwartz
Structure 17 (9), 1156-1168, 2009
2172009
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs
DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ...
Nature structural & molecular biology 28 (7), 573-582, 2021
2052021
Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel
SG Brohawn, EB Campbell, R MacKinnon
Proceedings of the National Academy of Sciences 110 (6), 2129-2134, 2013
1302013
A global benchmark study using affinity-based biosensors
RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ...
Analytical biochemistry 386 (2), 194-216, 2009
1242009
How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2
SG Brohawn
Annals of the New York Academy of Sciences 1352 (1), 20-32, 2015
1192015
Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs
DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ...
BioRxiv, 2020
1032020
Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
DM Kern, SC Oh, RK Hite, SG Brohawn
Elife 8, e42636, 2019
1022019
Molecular architecture of the Nup84–Nup145C–Sec13 edge element in the nuclear pore complex lattice
SG Brohawn, TU Schwartz
Nature structural & molecular biology 16 (11), 1173-1177, 2009
962009
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier
SG Brohawn, W Wang, A Handler, EB Campbell, JR Schwarz, ...
Elife 8, e50403, 2019
912019
Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane
B Sorum, RA Rietmeijer, K Gopakumar, H Adesnik, SG Brohawn
Proceedings of the National Academy of Sciences 118 (6), e2006980118, 2021
902021
High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks
S Sridharan, MA Gajowa, MB Ogando, UK Jagadisan, L Abdeladim, ...
Neuron 110 (7), 1139-1155. e6, 2022
682022
The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture
NC Leksa, SG Brohawn, TU Schwartz
Structure 17 (8), 1082-1091, 2009
672009
Structural basis for pH gating of the two-pore domain K+ channel TASK2
B Li, RA Rietmeijer, SG Brohawn
Nature 586 (7829), 457-462, 2020
572020
Structure of SARS-CoV-2 M protein in lipid nanodiscs
KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth, SG Brohawn
Elife 11, e81702, 2022
472022
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