Accurate de novo design of hyperstable constrained peptides G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ... Nature 538 (7625), 329-335, 2016 | 415 | 2016 |
Comprehensive computational design of ordered peptide macrocycles P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ... Science 358 (6369), 1461-1466, 2017 | 183 | 2017 |
Accurate de novo design of membrane-traversing macrocycles G Bhardwaj, J O’Connor, S Rettie, YH Huang, TA Ramelot, VK Mulligan, ... Cell 185 (19), 3520-3532. e26, 2022 | 82 | 2022 |
Phylogenetic profiles reveal evolutionary relationships within the “twilight zone” of sequence similarity GS Chang, Y Hong, KD Ko, G Bhardwaj, EC Holmes, RL Patterson, ... Proceedings of the National Academy of Sciences 105 (36), 13474, 2008 | 57 | 2008 |
Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor W Guo, R Liu, G Bhardwaj, JC Yang, C Changou, AH Ma, A Mazloom, ... Cell death & disease 5 (9), e1409-e1409, 2014 | 51 | 2014 |
A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo TC Shih, R Liu, G Fung, G Bhardwaj, PM Ghosh, KS Lam Molecular cancer therapeutics 16 (7), 1212-1223, 2017 | 40 | 2017 |
TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion DB van Rossum, D Oberdick, Y Rbaibi, G Bhardwaj, RK Barrow, ... Journal of Biological Chemistry 283 (49), 34384-34392, 2008 | 38 | 2008 |
Reevaluation of the evolutionary events within recA/RAD51 phylogeny SV Chintapalli, G Bhardwaj, J Babu, L Hadjiyianni, Y Hong, GK Todd, ... BMC genomics 14, 1-10, 2013 | 35 | 2013 |
Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A G Kaplan, F Lee, M Onda, E Kolyvas, G Bhardwaj, D Baker, I Pastan Toxins 8 (8), 217, 2016 | 33 | 2016 |
Cyclic peptide structure prediction and design using AlphaFold SA Rettie, KV Campbell, AK Bera, A Kang, S Kozlov, J De La Cruz, ... bioRxiv, 2023 | 29 | 2023 |
Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin SV Chintapalli, G Bhardwaj, R Patel, N Shah, RL Patterson, ... PloS one 10 (6), e0128496, 2015 | 29 | 2015 |
Covalent chemical ligation strategy for mono-and polyclonal immunoglobulins at their nucleotide binding sites D Lac, C Feng, G Bhardwaj, H Le, J Tran, L Xing, G Fung, R Liu, H Cheng, ... Bioconjugate chemistry 27 (1), 159-169, 2016 | 28 | 2016 |
PHYRN: a robust method for phylogenetic analysis of highly divergent sequences G Bhardwaj, KD Ko, Y Hong, Z Zhang, NL Ho, SV Chintapalli, LA Kline, ... PLoS One 7 (4), e34261, 2012 | 22 | 2012 |
Phylogenetic profiles reveal structural and functional determinants of lipid-binding Y Hong, D Chalkia, KD Ko, G Bhardwaj, GS Chang, DB van Rossum, ... Journal of proteomics & bioinformatics 2, 139, 2009 | 17 | 2009 |
Phylogenetic profiles as a unified framework for measuring protein structure, function and evolution KD Ko, Y Hong, GS Chang, G Bhardwaj, DB Van Rossum, RL Patterson Arxiv preprint arXiv:0806.2394, 2008 | 16 | 2008 |
Exploring phospholipase C-coupled Ca21 signalling networks using boolean modelling G Bhardwaj, CP Wells, R Albert, DB van Rossum, RL Patterson Systems Biology, IET 5 (3), 174-184, 2011 | 14 | 2011 |
Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor E Muratspahić, K Deibler, J Han, N Tomašević, KB Jadhav, AL Olivé-Marti, ... Nature communications 14 (1), 8064, 2023 | 11 | 2023 |
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors W Guo, R Liu, G Bhardwaj, AH Ma, C Changou, JC Yang, Y Li, C Feng, ... PLoS One 8 (8), e70910, 2013 | 9 | 2013 |
Predicting Protein Folds with Fold-Specific PSSM Libraries Y Hong, SV Chintapalli, KD Ko, G Bhardwaj, Z Zhang, D van Rossum, ... PloS one 6 (6), e20557, 2011 | 8 | 2011 |
Brainstorming through the sequence universe: theories on the protein problem KD Ko, Y Hong, G Bhardwaj, TM Killick, DB Van Rossum, RL Patterson Arxiv preprint arXiv:0911.0652, 2009 | 8 | 2009 |