C2H2 zinc finger proteins greatly expand the human regulatory lexicon HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ... Nature biotechnology 33 (5), 555-562, 2015 | 352 | 2015 |
Current and future resources for functional metagenomics KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles Frontiers in microbiology 6, 1196, 2015 | 185 | 2015 |
Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays KN Lam, H van Bakel, AG Cote, A van der Ven, TR Hughes Nucleic acids research 39 (11), 4680-4690, 2011 | 116 | 2011 |
Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes KN Lam, M Alexander, PJ Turnbaugh Cell host & microbe 26 (1), 22-34, 2019 | 111 | 2019 |
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ... Cell Reports 37 (5), 2021 | 102 | 2021 |
CRISPR-Cas system of a prevalent human gut bacterium reveals hyper-targeting against phages in a human virome catalog P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ... Cell Host & Microbe 26 (3), 325-335. e5, 2019 | 56 | 2019 |
A genomic toolkit for the mechanistic dissection of intractable human gut bacteria JE Bisanz, P Soto-Perez, C Noecker, AA Aksenov, KN Lam, GE Kenney, ... Cell Host & Microbe 27 (6), 1001-1013. e9, 2020 | 54 | 2020 |
Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism P Spanogiannopoulos, TS Kyaw, BGH Guthrie, PH Bradley, JV Lee, ... Nature microbiology 7 (10), 1605-1620, 2022 | 51 | 2022 |
Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries KN Lam, TC Charles Microbiome 3, 1-11, 2015 | 27 | 2015 |
Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles BMC microbiology 10, 1-10, 2010 | 27 | 2010 |
Evaluation of a pooled strategy for high-throughput sequencing of cosmid clones from metagenomic libraries KN Lam, MW Hall, K Engel, G Vey, J Cheng, JD Neufeld, TC Charles PLoS One 9 (6), e98968, 2014 | 26 | 2014 |
Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut Actinobacteria JE Bisanz, P Soto-Perez, KN Lam, EN Bess, HJ Haiser, E Allen-Vercoe, ... BioRxiv, 304840, 2018 | 20 | 2018 |
Current and future resources for functional metagenomics. Front Microbiol 6: 1196 KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles | 15 | 2015 |
Developing a Bacteroides System for Function-Based Screening of DNA from the Human Gut Microbiome KN Lam, EC Martens, TC Charles Msystems 3 (3), 10.1128/msystems. 00195-17, 2018 | 12 | 2018 |
Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance P Spanogiannopoulos, PH Bradley, J Melamed, YNA Malig, KN Lam, ... BioRxiv 10, 820084, 2019 | 5 | 2019 |
Metagenomic cosmid libraries suitable for functional screening in proteobacteria J Cheng, KN Lam, K Engel, M Hall, JD Neufeld, TC Charles Functional Metagenomics: Tools and Applications, 1-11, 2017 | 4 | 2017 |
Detection of non-small cell lung and bladder cancer signatures in peripheral blood using a novel antibody-free chromatin capture assay K Lai, K Dilger, R Cunningham, T Barnes, K Truong, K Lam, R Boquiren, ... Cancer Research 84 (6_Supplement), 5028-5028, 2024 | | 2024 |
Extracting Regulatory Active Chromatin Footprint from Cell-Free DNA K Lai, K Dilger, R Cunningham, K Lam, R Boquiren, K Troung, M Louie, ... | | 2024 |
Extracting Regulatory Active Chromatin Footprint from Cell-Free DNA D Abdueva, K Lai, K Dilger, R Cunningham, K Lam, R Boquiren, K Troung, ... | | 2024 |
Phage-mediated delivery of genes to gut microbiome K Lam, P Spanogiannopoulos, P Turnbaugh US Patent App. 17/923,865, 2023 | | 2023 |