Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors S Castellano, D Kuck, M Viviano, J Yoo, F López-Vallejo, P Conti, ... Journal of medicinal chemistry 54 (21), 7663-7677, 2011 | 198 | 2011 |
Integrating virtual screening and combinatorial chemistry for accelerated drug discovery F Lopez-Vallejo, T Caulfield, K Martinez-Mayorga, M A Giulianotti, A Nefzi, ... Combinatorial Chemistry &# 38; High Throughput Screening 14 (6), 475-487, 2011 | 189 | 2011 |
Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach JL Medina-Franco, F López-Vallejo, D Kuck, F Lyko Molecular diversity 15 (2), 293-304, 2011 | 161 | 2011 |
Expanding the medicinally relevant chemical space with compound libraries F López-Vallejo, MA Giulianotti, RA Houghten, JL Medina-Franco Drug discovery today 17 (13-14), 718-726, 2012 | 160 | 2012 |
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches JJ Ramírez-Espinosa, MY Rios, S López-Martínez, F López-Vallejo, ... European journal of medicinal chemistry, 2011 | 148 | 2011 |
Visualization of molecular fingerprints JR Owen, IT Nabney, JL Medina-Franco, F López-Vallejo Journal of Chemical Information and Modeling 51 (7), 1552, 2011 | 77 | 2011 |
Benzotriazoles and indazoles are scaffolds with biological activity against Entamoeba histolytica F López-Vallejo, R Castillo, L Yépez-Mulia, JL Medina-Franco Journal of biomolecular Screening 16 (8), 862-868, 2011 | 66 | 2011 |
Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity, and human cell toxicity N Bionda, M Stawikowski, R Stawikowska, M Cudic, F López‐Vallejo, ... ChemMedChem 7 (5), 871-882, 2012 | 63 | 2012 |
Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: Ex vivo and in silico studies MY Rios, S López-Martínez, F López-Vallejo, JL Medina-Franco, ... Fitoterapia 83 (6), 1023-1029, 2012 | 60 | 2012 |
Structural Reassignment, Absolute Configuration, and Conformation of Hypurticin, a Highly Flexible Polyacyloxy-6-heptenyl-5,6-dihydro-2H-pyran-2-one JA Mendoza-Espinoza, F López-Vallejo, M Fragoso-Serrano, ... Journal of natural products 72 (4), 700-708, 2009 | 43 | 2009 |
Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl) amino]-1, 3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities G Navarrete-Vázquez, MG Morales-Vilchis, S Estrada-Soto, ... European Journal of Medicinal Chemistry 74, 179-186, 2014 | 39 | 2014 |
Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits FJ Luna-Vázquez, C Ibarra-Alvarado, A Rojas-Molina, A Romo-Mancillas, ... Molecules 21 (1), 78, 2016 | 38 | 2016 |
A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions. R Kraft, A Kahn, JL Medina-Franco, ML Orlowski, C Baynes, ... Disease models & mechanisms 6 (1), 217-235, 2013 | 37 | 2013 |
Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent G Navarrete-Vázquez, A Alaniz-Palacios, S Hidalgo-Figueroa, ... Bioorganic & medicinal chemistry letters 23 (11), 3244-3247, 2013 | 36 | 2013 |
Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis‐Diazacyclic Libraries F López‐Vallejo, A Nefzi, A Bender, JR Owen, IT Nabney, RA Houghten, ... Chemical Biology & Drug Design 77 (5), 328-342, 2011 | 35 | 2011 |
Behavioral changes induced through adenosine A2A receptor ligands in a rat depression model induced by olfactory bulbectomy KM Padilla, A Quintanar‐Setephano, F López‐Vallejo, LC Berumen, ... Brain and behavior 8 (5), e00952, 2018 | 34 | 2018 |
Diseño de fármacos asistido por computadora JL Medino-Franco, F López-Vallejo, R Castillo Educación química 17 (4), 452-457, 2006 | 34* | 2006 |
Molecular docking of the highly hypolipidemic agent α-asarone with the catalytic portion of HMG-CoA reductase JL Medina-Franco, F López-Vallejo, S Rodríguez-Morales, R Castillo, ... Bioorganic & medicinal chemistry letters 15 (4), 989-994, 2005 | 32 | 2005 |
Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11β-HSD 1 JJ Ramírez-Espinosa, S García-Jiménez, MY Rios, JL Medina-Franco, ... Phytomedicine 20 (7), 571-576, 2013 | 31 | 2013 |
Systematic mining of generally recognized as safe (GRAS) flavor chemicals for bioactive compounds K Martinez-Mayorga, TL Peppard, F López-Vallejo, AB Yongye, ... Journal of agricultural and food chemistry 61 (31), 7507-7514, 2013 | 30 | 2013 |