Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock T Vogl, K Tenbrock, S Ludwig, N Leukert, C Ehrhardt, MAD Van Zoelen, ... Nature medicine 13 (9), 1042-1049, 2007 | 1575 | 2007 |
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade S Pleschka, T Wolff, C Ehrhardt, G Hobom, O Planz, UR Rapp, S Ludwig Nature cell biology 3 (3), 301-305, 2001 | 646 | 2001 |
Coronaviruses and SARS-CoV-2: a brief overview S Ludwig, A Zarbock Anesthesia & Analgesia 131 (1), 93-96, 2020 | 457 | 2020 |
Caspase 3 activation is essential for efficient influenza virus propagation WJ Wurzer, O Planz, C Ehrhardt, M Giner, T Silberzahn, S Pleschka, ... The EMBO journal, 2003 | 435 | 2003 |
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes T Vogl, S Ludwig, M Goebeler, A Strey, IS Thorey, R Reichelt, D Foell, ... blood 104 (13), 4260-4268, 2004 | 431 | 2004 |
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses C Ehrhardt, T Wolff, S Pleschka, O Planz, W Beermann, JG Bode, ... Journal of virology 81 (7), 3058-3067, 2007 | 426 | 2007 |
IFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3 JG Bode, S Ludwig, C Ehrhardt, A Erhardt, U Albrecht, F Schaper, ... The FASEB Journal 17 (3), 1-16, 2003 | 416 | 2003 |
The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells T Eierhoff, ER Hrincius, U Rescher, S Ludwig, C Ehrhardt PLoS pathogens 6 (9), e1001099, 2010 | 364 | 2010 |
Influenza A virus inhibits type I IFN signaling via NF-κB-dependent induction of SOCS-3 expression EK Pauli, M Schmolke, T Wolff, D Viemann, J Roth, JG Bode, S Ludwig PLoS pathogens 4 (11), e1000196, 2008 | 333 | 2008 |
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity M Hoffmann, H Hofmann-Winkler, JC Smith, N Krüger, P Arora, ... EBioMedicine 65, 2021 | 325 | 2021 |
Multiple signaling pathways regulate NF-κB–dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells M Goebeler, R Gillitzer, K Kilian, K Utzel, EB Bröcker, UR Rapp, ... Blood, The Journal of the American Society of Hematology 97 (1), 46-55, 2001 | 317 | 2001 |
NF-κB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation WJ Wurzer, C Ehrhardt, S Pleschka, F Berberich-Siebelt, T Wolff, ... Journal of Biological Chemistry 279 (30), 30931-30937, 2004 | 313 | 2004 |
Bivalent role of the phosphatidylinositol‐3‐kinase (PI3K) during influenza virus infection and host cell defence C Ehrhardt, H Marjuki, T Wolff, B Nürnberg, O Planz, S Pleschka, ... Cellular microbiology 8 (8), 1336-1348, 2006 | 293 | 2006 |
Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells S Ludwig, S Pleschka, O Planz, T Wolff Cellular microbiology 8 (3), 375-386, 2006 | 273 | 2006 |
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors S Ludwig, X Wang, C Ehrhardt, H Zheng, N Donelan, O Planz, S Pleschka, ... Journal of virology 76 (21), 11166-11171, 2002 | 272 | 2002 |
Activation of NF-κB via the IκB kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells A Denk, M Goebeler, S Schmid, I Berberich, O Ritz, D Lindemann, ... Journal of Biological Chemistry 276 (30), 28451-28458, 2001 | 270 | 2001 |
The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway S Ludwig, A Hoffmeyer, M Goebeler, K Kilian, H Häfner, B Neufeld, ... Journal of Biological Chemistry 273 (4), 1917-1922, 1998 | 246 | 1998 |
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways S Ludwig, K Engel, A Hoffmeyer, G Sithanandam, B Neufeld, D Palm, ... Molecular and cellular biology, 1996 | 234 | 1996 |
Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF‐κB‐inhibiting activity I Mazur, WJ Wurzer, C Ehrhardt, S Pleschka, P Puthavathana, ... Cellular microbiology 9 (7), 1683-1694, 2007 | 229 | 2007 |
Influenza-virus-induced signaling cascades: targets for antiviral therapy? S Ludwig, O Planz, S Pleschka, T Wolff Trends in molecular medicine 9 (2), 46-52, 2003 | 227 | 2003 |