| FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity PC Mahon, K Hirota, GL Semenza Genes & development 15 (20), 2675-2686, 2001 | 1849 | 2001 |
| Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and … R Fukuda, K Hirota, F Fan, Y Do Jung, LM Ellis, GL Semenza Journal of Biological Chemistry 277 (41), 38205-38211, 2002 | 1031 | 2002 |
| AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1 K Hirota, M Matsui, S Iwata, A Nishiyama, K Mori, J Yodoi Proceedings of the National Academy of Sciences 94 (8), 3633-3638, 1997 | 1026 | 1997 |
| Identification of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 as a negative regulator of thioredoxin function and expression A Nishiyama, M Matsui, S Iwata, K Hirota, H Masutani, H Nakamura, ... Journal of Biological Chemistry 274 (31), 21645-21650, 1999 | 836 | 1999 |
| Distinct roles of thioredoxin in the cytoplasm and in the nucleus: a two-step mechanism of redox regulation of transcription factor NF-κB K Hirota, M Murata, Y Sachi, H Nakamura, J Takeuchi, K Mori, J Yodoi Journal of Biological Chemistry 274 (39), 27891-27897, 1999 | 782 | 1999 |
| Cell type–specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia … BD Kelly, SF Hackett, K Hirota, Y Oshima, Z Cai, S Berg-Dixon, A Rowan, ... Circulation research 93 (11), 1074-1081, 2003 | 781 | 2003 |
| Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: their stabilization and redox signal‐induced interaction with CBP/p300 M Ema, K Hirota, J Mimura, H Abe, J Yodoi, K Sogawa, L Poellinger, ... The EMBO journal, 1999 | 764 | 1999 |
| Regulation of angiogenesis by hypoxia-inducible factor 1 K Hirota, GL Semenza Critical reviews in oncology/hematology 59 (1), 15-26, 2006 | 673 | 2006 |
| Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia SO Ang, H Chen, K Hirota, VR Gordeuk, J Jelinek, Y Guan, E Liu, ... Nature genetics 32 (4), 614-621, 2002 | 616 | 2002 |
| Thioredoxin-dependent redox regulation of p53-mediated p21 activation M Ueno, H Masutani, RJ Arai, A Yamauchi, K Hirota, T Sakai, T Inamoto, ... Journal of Biological Chemistry 274 (50), 35809-35815, 1999 | 532 | 1999 |
| Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling K Kasuno, S Takabuchi, K Fukuda, S Kizaka-Kondoh, J Yodoi, T Adachi, ... Journal of Biological Chemistry 279 (4), 2550-2558, 2004 | 296 | 2004 |
| Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases K Hirota, GL Semenza Biochemical and biophysical research communications 338 (1), 610-616, 2005 | 286 | 2005 |
| Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer T Hiraga, S Kizaka-Kondoh, K Hirota, M Hiraoka, T Yoneda Cancer research 67 (9), 4157-4163, 2007 | 280 | 2007 |
| Redox control of resistance to cis-diamminedichloroplatinum (II)(CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity. T Sasada, S Iwata, N Sato, Y Kitaoka, K Hirota, K Nakamura, A Nishiyama, ... The Journal of clinical investigation 97 (10), 2268-2276, 1996 | 257 | 1996 |
| Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation SJ Wei, A Botero, K Hirota, CM Bradbury, S Markovina, A Laszlo, DR Spitz, ... Cancer research 60 (23), 6688-6695, 2000 | 246 | 2000 |
| Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-κB, AP-1, and CREB activation in HEK293 cells K Hirota, M Matsui, M Murata, Y Takashima, FS Cheng, T Itoh, K Fukuda, ... Biochemical and biophysical research communications 274 (1), 177-182, 2000 | 241 | 2000 |
| Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function Y Makino, N Yoshikawa, K Okamoto, K Hirota, J Yodoi, I Makino, ... Journal of Biological Chemistry 274 (5), 3182-3188, 1999 | 240 | 1999 |
| Rac1 activity is required for the activation of hypoxia-inducible factor 1 K Hirota, GL Semenza Journal of Biological Chemistry 276 (24), 21166-21172, 2001 | 219 | 2001 |
| Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution Y Matsuo, S Komiya, Y Yasumizu, Y Yasuoka, K Mizushima, T Takagi, ... BMC microbiology 21, 1-13, 2021 | 215 | 2021 |
| UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α Y Goto, L Zeng, CJ Yeom, Y Zhu, A Morinibu, K Shinomiya, M Kobayashi, ... Nature communications 6 (1), 6153, 2015 | 213 | 2015 |
Yoshiyuki MatsuoKansai Medical University在 hirakata.kmu.ac.jp 的电子邮件经过验证
