Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia: a mechanism of O2 sensing NS Chandel, DS McClintock, CE Feliciano, TM Wood, JA Melendez, ... Journal of Biological Chemistry 275 (33), 25130-25138, 2000 | 2378 | 2000 |
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production N Li, K Ragheb, G Lawler, J Sturgis, B Rajwa, JA Melendez, JP Robinson Journal of Biological Chemistry 278 (10), 8516-8525, 2003 | 1552 | 2003 |
Mitochondrial redox control of matrix metalloproteinases KK Nelson, JA Melendez Free Radical Biology and Medicine 37 (6), 768-784, 2004 | 500 | 2004 |
Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury J Bai, AM Rodriguez, JA Melendez, AI Cederbaum Journal of Biological Chemistry 274 (37), 26217-26224, 1999 | 362 | 1999 |
Redox control of senescence and age-related disease A Chandrasekaran, MPS Idelchik, JA Melendez Redox biology 11, 91-102, 2017 | 358 | 2017 |
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation KM Connor, S Subbaram, KJ Regan, KK Nelson, JE Mazurkiewicz, ... Journal of Biological Chemistry 280 (17), 16916-16924, 2005 | 293 | 2005 |
Mitochondrial ROS control of cancer MPS Idelchik, U Begley, TJ Begley, JA Melendez Seminars in cancer biology 47, 57-66, 2017 | 273 | 2017 |
Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation AC Ranganathan, KK Nelson, AM Rodriguez, KH Kim, GB Tower, ... Journal of Biological Chemistry 276 (17), 14264-14270, 2001 | 198 | 2001 |
Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells KM Connor, N Hempel, KK Nelson, G Dabiri, A Gamarra, J Belarmino, ... Cancer research 67 (21), 10260-10267, 2007 | 195 | 2007 |
Manganese superoxide dismutase (Sod2) and redox-control of signaling events that drive metastasis N Hempel, P M Carrico, JA Melendez Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2011 | 193 | 2011 |
Elevated Sod2 Activity Augments Matrix Metalloproteinase Expression: Evidence for the Involvement of Endogenous Hydrogen Peroxide in Regulating Metastasis KK Nelson, AC Ranganathan, J Mansouri, AM Rodriguez, KM Providence, ... Clinical cancer research 9 (1), 424-432, 2003 | 179 | 2003 |
Superoxide Dismutase B Gene (sodB)-Deficient Mutants of Francisella tularensis Demonstrate Hypersensitivity to Oxidative Stress and Attenuated Virulence CS Bakshi, M Malik, K Regan, JA Melendez, DW Metzger, VM Pavlov, ... Journal of bacteriology 188 (17), 6443-6448, 2006 | 165 | 2006 |
Mitochondrial or cytosolic catalase reverses the MnSOD-dependent inhibition of proliferation by enhancing respiratory chain activity, net ATP production, and decreasing the … AM Rodrı́guez, PM Carrico, JE Mazurkiewicz, JA Meléndez Free Radical Biology and Medicine 29 (9), 801-813, 2000 | 155 | 2000 |
Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis M Malik, CS Bakshi, K McCabe, SV Catlett, A Shah, R Singh, PL Jackson, ... The Journal of Immunology 178 (2), 1013-1020, 2007 | 138 | 2007 |
Redox-control of matrix metalloproteinase-1: a critical link between free radicals, matrix remodeling and degenerative disease S Kar, S Subbaram, PM Carrico, JA Melendez Respiratory physiology & neurobiology 174 (3), 299-306, 2010 | 136 | 2010 |
Altered redox status accompanies progression to metastatic human bladder cancer N Hempel, H Ye, B Abessi, B Mian, JA Melendez Free Radical Biology and Medicine 46 (1), 42-50, 2009 | 123 | 2009 |
DPI induces mitochondrial superoxide-mediated apoptosis N Li, K Ragheb, G Lawler, J Sturgis, B Rajwa, JA Melendez, JP Robinson Free Radical Biology and Medicine 34 (4), 465-477, 2003 | 119 | 2003 |
Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation DR Pimentel, T Adachi, Y Ido, T Heibeck, B Jiang, Y Lee, JA Melendez, ... Journal of molecular and cellular cardiology 41 (4), 613-622, 2006 | 110 | 2006 |
Potential mechanisms for the inhibition of tumor cell growth by manganese superoxide dismutase KH Kim, AM Rodriguez, PM Carrico, JA Melendez Antioxidants and redox signaling 3 (3), 361-373, 2001 | 98 | 2001 |
Reactive oxygen species control senescence‐associated matrix metalloproteinase‐1 through c‐Jun‐N‐terminal kinase J Dasgupta, S Kar, R Liu, J Joseph, B Kalyanaraman, SJ Remington, ... Journal of cellular physiology 225 (1), 52-62, 2010 | 97 | 2010 |