| Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface YL Tsai, Y Zhang, CC Tseng, R Stanciauskas, F Pinaud, AS Lee Journal of Biological Chemistry 290 (13), 8049-8064, 2015 | 189 | 2015 |
| Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI (3, 4, 5) P3 production Y Zhang, CC Tseng, YL Tsai, X Fu, R Schiff, AS Lee PloS one 8 (11), e80071, 2013 | 172 | 2013 |
| Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling YL Tsai, DP Ha, H Zhao, AJ Carlos, S Wei, TK Pun, K Wu, E Zandi, K Kelly, ... Proceedings of the National Academy of Sciences 115 (18), E4245-E4254, 2018 | 127 | 2018 |
| ER residential chaperone GRP78 unconventionally relocalizes to the cell surface via endosomal transport R Van Krieken, YL Tsai, AJ Carlos, DP Ha, AS Lee Cellular and Molecular Life Sciences 78, 5179-5195, 2021 | 30 | 2021 |
| Cell surface GRP78: anchoring and translocation mechanisms and therapeutic potential in cancer YL Tsai, AS Lee Cell surface GRP78, a new paradigm in signal transduction biology, 41-62, 2018 | 18 | 2018 |
| Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress … DP Ha, YL Tsai, AS Lee Neoplasia 23 (12), 1213-1226, 2021 | 17 | 2021 |
| A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function WL Lo, M Kuhlmann, G Rizzuto, HA Ekiz, EM Kolawole, MP Revelo, ... Nature immunology 24 (4), 676-689, 2023 | 15 | 2023 |
| TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments YL Tsai, M Arias-Badia, TA Kadlecek, YM Lwin, A Srinath, NH Shah, ... Immunity 56 (12), 2682-2698. e9, 2023 | 4 | 2023 |
| Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling J Eggert, WM Zinzow-Kramer, Y Hu, EM Kolawole, YL Tsai, A Weiss, ... Science signaling 17 (822), eadh0439, 2024 | 3 | 2024 |
| Src inhibitor to block cell surface grp78 expression AS Lee, YL Tsai | 1 | 2017 |
| Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness J Eggert, WM Zinzow-Kramer, Y Hu, YL Tsai, A Weiss, K Salaita, ... bioRxiv, 2023 | | 2023 |
| Overcoming inhibitory constraints to TCR signaling by targeting the pH-sensitive phosphatase suppressor of T-cell receptor signaling 1 (STS1) YL Tsai, MA Badia, TA Kadlecek, NH Shah, L Fong, A Weiss The Journal of Immunology 208 (1_Supplement), 166.14-166.14, 2022 | | 2022 |
| Abstract LB199: Trafficking of Semaphorin4D is regulated by endoplasmic reticulum chaperone GRP78 A Carlos, YL Tsai, Y Ma, A Lee Cancer Research 81 (13_Supplement), LB199-LB199, 2021 | | 2021 |
| Cell Surface Translocation Mechanism of Stress-Inducible GRP78 in Human Cancer YL Tsai University of Southern California, 2018 | | 2018 |
| Abstract SY13-03: GRP78/BiP: Cancer's comrade in crime AS Lee, J Shen, D Rangel, CC Tseng, YL Tsai, DP Ha, H Zhao, L Dubeau Cancer Research 77 (13_Supplement), SY13-03-SY13-03, 2017 | | 2017 |
| Characterization and Mechanism of Stress-induced Translocation of 78-kilodalton Glucose Regulated Protein (GRP78) to the Cell Surface Yuan-Li Tsai1, Yi Zhang1, Chun-Chih Tseng1 … YL Tsai, Y Zhang, CC Tseng, R Stanciauskas | | 2015 |
