| Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease C Kuscu, S Arslan, R Singh, J Thorpe, M Adli Nature biotechnology 32 (7), 677-683, 2014 | 950 | 2014 |
| CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations C Kuscu, M Parlak, T Tufan, J Yang, K Szlachta, X Wei, R Mammadov, ... Nature methods 14 (7), 710-712, 2017 | 374 | 2017 |
| Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo O Abdel-Wahab, J Gao, M Adli, A Dey, T Trimarchi, YR Chung, C Kuscu, ... Journal of Experimental Medicine 210 (12), 2641-2659, 2013 | 366 | 2013 |
| Cas9-chromatin binding information enables more accurate CRISPR off-target prediction R Singh, C Kuscu, A Quinlan, Y Qi, M Adli Nucleic acids research 43 (18), e118-e118, 2015 | 238 | 2015 |
| Live cell imaging of low-and non-repetitive chromosome loci using CRISPR-Cas9 P Qin, M Parlak, C Kuscu, J Bandaria, M Mir, K Szlachta, R Singh, ... Nature communications 8 (1), 14725, 2017 | 236 | 2017 |
| Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration K Zarrabi, A Dufour, J Li, C Kuscu, A Pulkoski-Gross, J Zhi, Y Hu, ... Journal of Biological Chemistry 286 (38), 33167-33177, 2011 | 236 | 2011 |
| miR-181a-5p inhibits cancer cell migration and angiogenesis via downregulation of matrix metalloproteinase-14 Y Li, C Kuscu, A Banach, Q Zhang, A Pulkoski-Gross, D Kim, J Liu, E Roth, ... Cancer research 75 (13), 2674-2685, 2015 | 198 | 2015 |
| Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides A Dufour, S Zucker, NS Sampson, C Kuscu, J Cao Journal of Biological Chemistry 285 (46), 35944-35956, 2010 | 168 | 2010 |
| Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9 A Dufour, NS Sampson, J Li, C Kuscu, RC Rizzo, JL DeLeon, J Zhi, ... Cancer research 71 (14), 4977-4988, 2011 | 146 | 2011 |
| Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration NA Evensen, C Kuscu, HL Nguyen, K Zarrabi, A Dufour, P Kadam, Y Hu, ... Journal of the National Cancer Institute 105 (18), 1402-1416, 2013 | 136 | 2013 |
| Small molecule inhibitor of CBFβ-RUNX binding for RUNX transcription factor driven cancers A Illendula, J Gilmour, J Grembecka, VSS Tirumala, A Boulton, ... EBioMedicine 8, 117-131, 2016 | 112 | 2016 |
| CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response K Szlachta, C Kuscu, T Tufan, SJ Adair, S Shang, AD Michaels, ... Nature communications 9 (1), 4275, 2018 | 76 | 2018 |
| Transcriptional and Epigenetic Regulation of KIAA1199 Gene Expression in Human Breast Cancer C Kuscu, N Evensen, D Kim, YJ Hu, S Zucker, J Cao Public Library of Science 7 (9), e44661, 2012 | 70 | 2012 |
| Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells X Wei, J Yang, SJ Adair, H Ozturk, C Kuscu, KY Lee, WJ Kane, PE O’Hara, ... Proceedings of the National Academy of Sciences 117 (45), 28068-28079, 2020 | 63 | 2020 |
| Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP) NA Evensen, Y Li, C Kuscu, J Liu, J Cathcart, A Banach, Q Zhang, E Li, ... Oncotarget 6 (24), 20723, 2015 | 62 | 2015 |
| Two distinct categories of focal deletions in cancer genomes M Rajaram, J Zhang, T Wang, J Li, C Kuscu, H Qi, M Kato, V Grubor, ... PLoS One 8 (6), e66264, 2013 | 58 | 2013 |
| CRISPR-Cas9-AID base editor is a powerful gain-of-function screening tool C Kuscu, M Adli Nature methods 13 (12), 983-984, 2016 | 38 | 2016 |
| Temporal and spatial epigenome editing allows precise gene regulation in mammalian cells C Kuscu, R Mammadov, A Czikora, H Unlu, T Tufan, NL Fischer, S Arslan, ... Journal of molecular biology 431 (1), 111-121, 2019 | 36 | 2019 |
| CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia A Banach, YP Jiang, E Roth, C Kuscu, J Cao, RZ Lin Oncotarget 10 (42), 4307, 2019 | 32 | 2019 |
| FTY720 regulates mitochondria biogenesis in dendritic cells to prevent kidney ischemic reperfusion injury TV Rousselle, C Kuscu, C Kuscu, K Schlegel, LP Huang, M Namwanje, ... Frontiers in Immunology 11, 1278, 2020 | 28 | 2020 |
Mazhar AdliNorthwestern University在 northwestern.edu 的电子邮件经过验证
