The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine SDC Griffin, LP Beales, DS Clarke, O Worsfold, SD Evans, J Jaeger, ... FEBS letters 535 (1-3), 34-38, 2003 | 714 | 2003 |
Hepatitis C virus NS5A: tales of a promiscuous protein A Macdonald, M Harris Journal of General Virology 85 (9), 2485-2502, 2004 | 520 | 2004 |
The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade A Street, A Macdonald, K Crowder, M Harris Journal of Biological Chemistry 279 (13), 12232-12241, 2004 | 283 | 2004 |
Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production AL Wozniak, S Griffin, D Rowlands, M Harris, MK Yi, SM Lemon, ... PLoS Pathog 6 (9), e1001087, 2010 | 248 | 2010 |
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to … SDC Griffin, R Harvey, DS Clarke, WS Barclay, M Harris, DJ Rowlands Journal of General Virology 85 (2), 451-461, 2004 | 232 | 2004 |
Physical and functional interaction of Nef with Lck HIV-1 Nef-induced T-cell signaling defects Y Collette, H Dutartre, A Benziane, F Ramos-Morales, R Benarous, ... Journal of Biological Chemistry 271 (11), 6333-6341, 1996 | 206 | 1996 |
Construction of genetically engineered baculovirus insecticides containing the Bacillus thuringiensis subsp. kurstaki HD-73 delta endotoxin AT Merryweather, U Weyer, MPG Harris, M Hirst, T Booth, RD Possee Journal of General Virology 71 (7), 1535-1544, 1990 | 205 | 1990 |
The Hepatitis C Virus Non-structural NS5A Protein Inhibits Activating Protein–1 Function by Perturbing Ras-ERK Pathway Signaling A Macdonald, K Crowder, A Street, C McCormick, K Saksela, M Harris Journal of Biological Chemistry 278 (20), 17775-17784, 2003 | 194 | 2003 |
Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro D Clarke, S Griffin, L Beales, CS Gelais, S Burgess, M Harris, D Rowlands Journal of Biological Chemistry 281 (48), 37057-37068, 2006 | 185 | 2006 |
HIV-1 Nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of Nef endocytotic signals and NF-κB activation E Olivetta, Z Percario, G Fiorucci, G Mattia, I Schiavoni, C Dennis, J Jäger, ... The Journal of Immunology 170 (4), 1716-1727, 2003 | 184 | 2003 |
Identification of the Nef-associated kinase as p21-activated kinase 2 GH Renkema, A Manninen, DA Mann, M Harris, K Saksela Current biology 9 (23), 1407-1411, 1999 | 181 | 1999 |
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase J Mankouri, PR Tedbury, S Gretton, ME Hughes, SDC Griffin, ML Dallas, ... Proceedings of the National Academy of Sciences 107 (25), 11549-11554, 2010 | 169 | 2010 |
Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular β-catenin and stimulation of β-catenin-responsive transcription A Street, A Macdonald, C McCormick, M Harris Journal of virology 79 (8), 5006-5016, 2005 | 168 | 2005 |
Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity R Welker, M Harris, B Cardel, HG Kräusslich Journal of virology 72 (11), 8833-8840, 1998 | 167 | 1998 |
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity A Macdonald, K Crowder, A Street, C McCormick, M Harris Journal of General Virology 85 (3), 721-729, 2004 | 163 | 2004 |
All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding TL Foster, T Belyaeva, NJ Stonehouse, AR Pearson, M Harris Journal of virology 84 (18), 9267-9277, 2010 | 155 | 2010 |
Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner TL Foster, P Gallay, NJ Stonehouse, M Harris Journal of virology 85 (14), 7460-7464, 2011 | 154 | 2011 |
Genotype‐dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel S Griffin, C StGelais, AM Owsianka, AH Patel, D Rowlands, M Harris Hepatology 48 (6), 1779-1790, 2008 | 153 | 2008 |
Hepatitis C virus NS5A: enigmatic but still promiscuous 10 years on! D Ross-Thriepland, M Harris Journal of General Virology 96 (4), 727-738, 2015 | 152 | 2015 |
Vps4 and the ESCRT-III complex are required for the release of infectious hepatitis C virus particles L Corless, CM Crump, SDC Griffin, M Harris Journal of General Virology 91 (2), 362-372, 2010 | 147 | 2010 |