Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 702 | 2022 |
De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 528 | 2023 |
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates A Courbet, D Endy, E Renard, F Molina, J Bonnet Science translational medicine 7 (289), 289ra83-289ra83, 2015 | 266 | 2015 |
Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... BioRxiv, 2022.12. 09.519842, 2022 | 182 | 2022 |
Hallucinating symmetric protein assemblies BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ... Science 378 (6615), 56-61, 2022 | 139 | 2022 |
Design of multi-scale protein complexes by hierarchical building block fusion Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ... Nature Communications 12 (1), 2294, 2021 | 60 | 2021 |
Top-down design of protein architectures with reinforcement learning ID Lutz, S Wang, C Norn, A Courbet, AJ Borst, YT Zhao, A Dosey, L Cao, ... Science 380 (6642), 266-273, 2023 | 55 | 2023 |
Computational design of mechanically coupled axle-rotor protein assemblies A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ... Science 376 (6591), 383-390, 2022 | 49 | 2022 |
Reconfigurable asymmetric protein assemblies through implicit negative design DD Sahtoe, F Praetorius, A Courbet, Y Hsia, BIM Wicky, NI Edman, ... Science 375 (6578), eabj7662, 2022 | 47 | 2022 |
Generation of ordered protein assemblies using rigid three-body fusion I Vulovic, Q Yao, YJ Park, A Courbet, A Norris, F Busch, A Sahasrabuddhe, ... Proceedings of the National Academy of Sciences 118 (23), e2015037118, 2021 | 38 | 2021 |
Bringing next‐generation diagnostics to the clinic through synthetic biology A Courbet, E Renard, F Molina EMBO molecular medicine 8 (9), 987-991, 2016 | 35 | 2016 |
Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices A Courbet, P Amar, F Fages, E Renard, F Molina Molecular Systems Biology 14 (4), e7845, 2018 | 33 | 2018 |
Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity A Courbet, N Bec, C Constant, C Larroque, M Pugniere, S El Messaoudi, ... PLoS One 12 (8), e0182022, 2017 | 27 | 2017 |
Accurate computational design of three-dimensional protein crystals Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MY Yaman, MJ Bick, ... Nature Materials 22 (12), 1556-1563, 2023 | 17 | 2023 |
Blueprinting extendable nanomaterials with standardized protein blocks TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ... Nature 627 (8005), 898-904, 2024 | 9 | 2024 |
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ... bioRxiv, 2020.07. 27.221333, 2020 | 8 | 2020 |
Computing with synthetic protocells A Courbet, F Molina, P Amar Acta biotheoretica 63 (3), 309-323, 2015 | 7 | 2015 |
Hallucination of closed repeat proteins containing central pockets L An, DR Hicks, D Zorine, J Dauparas, BIM Wicky, LF Milles, A Courbet, ... Nature Structural & Molecular Biology 30 (11), 1755-1760, 2023 | 6 | 2023 |
Self-assembly–based posttranslational protein oscillators O Kimchi, CP Goodrich, A Courbet, AI Curatolo, NB Woodall, D Baker, ... Science Advances 6 (51), eabc1939, 2020 | 6 | 2020 |
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates. Sci Transl Med 7: 289ra83–289ra83 A Courbet, D Endy, E Renard, F Molina, J Bonnet | 5 | 2015 |