Generation of T cells from human embryonic stem cell-derived hematopoietic zones F Timmermans, I Velghe, L Vanwalleghem, M De Smedt, ... The Journal of Immunology 182 (11), 6879-6888, 2009 | 249 | 2009 |
HIV rebound is predominantly fueled by genetically identical viral expansions from diverse reservoirs MA De Scheerder, B Vrancken, S Dellicour, T Schlub, E Lee, W Shao, ... Cell host & microbe 26 (3), 347-358. e7, 2019 | 146 | 2019 |
Active form of Notch imposes T cell fate in human progenitor cells M De Smedt, K Reynvoet, T Kerre, T Taghon, B Verhasselt, ... The Journal of Immunology 169 (6), 3021-3029, 2002 | 145 | 2002 |
Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength I Van de Walle, E Waegemans, J De Medts, G De Smet, M De Smedt, ... Journal of Experimental Medicine 210 (4), 683-697, 2013 | 126 | 2013 |
Nanobody based dual specific CARs S De Munter, J Ingels, G Goetgeluk, S Bonte, M Pille, K Weening, T Kerre, ... International journal of molecular sciences 19 (2), 403, 2018 | 107 | 2018 |
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations J Thalhammer, G Kindle, A Nieters, S Rusch, MRJ Seppänen, A Fischer, ... Journal of Allergy and Clinical Immunology 148 (5), 1332-1341. e5, 2021 | 93 | 2021 |
Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34+ cells TCC Kerre, G De Smet, M De Smedt, A Zippelius, MJ Pittet, AW Langerak, ... Blood, The Journal of the American Society of Hematology 99 (5), 1620-1626, 2002 | 82 | 2002 |
Both CD34+ 38+ and CD34+ 38− cells home specifically to the bone marrow of NOD/LtSZ scid/scid mice but show different kinetics in expansion TCC Kerre, G De Smet, M De Smedt, F Offner, J De Bosscher, J Plum, ... The Journal of Immunology 167 (7), 3692-3698, 2001 | 79 | 2001 |
Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells S Van Coppernolle, G Verstichel, F Timmermans, I Velghe, D Vermijlen, ... The Journal of immunology 183 (8), 4859-4870, 2009 | 66 | 2009 |
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate I Van de Walle, AC Dolens, K Durinck, K De Mulder, W Van Loocke, ... Nature communications 7 (1), 11171, 2016 | 64 | 2016 |
Human T Lymphopoiesis: In Vitro and In Vivo Study Models J Plum, M De Smedt, B Verhasselt, T Kerre, D Vanhecke, ... Annals of the New York Academy of Sciences 917 (1), 724-731, 2000 | 64 | 2000 |
Chimeric antigen receptor-T-cell therapy for B-cell hematological malignancies: an update of the pivotal clinical trial data G Roex, T Feys, Y Beguin, T Kerre, X Poiré, P Lewalle, P Vandenberghe, ... Pharmaceutics 12 (2), 194, 2020 | 63 | 2020 |
Bone marrow CD34+ cells generate fewer T cells in vitro with increasing age and following chemotherapy F Offner, T Kerre, M De Smedt, J Plum British journal of haematology 104 (4), 801-808, 1999 | 63 | 1999 |
In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis S Vanhee, K De Mulder, Y Van Caeneghem, G Verstichel, N Van Roy, ... haematologica 100 (2), 157, 2015 | 61 | 2015 |
Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients M Oyaert, MA De Scheerder, S Van Herrewege, G Laureys, S Van Assche, ... Frontiers in immunology 13, 858399, 2022 | 56 | 2022 |
Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients: a report from the EBMT Severe Aplastic Anemia Working Party PH Prata, DJ Eikema, B Afansyev, P Bosman, F Smiers, JL Diez-Martin, ... Bone marrow transplantation 55 (6), 1050-1058, 2020 | 56 | 2020 |
Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development M De Smedt, B Verhasselt, T Kerre, D Vanhecke, E Naessens, G Leclercq, ... The Journal of Immunology 164 (4), 1761-1767, 2000 | 56 | 2000 |
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation S Taveirne, S Wahlen, W Van Loocke, L Kiekens, E Persyn, E Van Ammel, ... Blood, The Journal of the American Society of Hematology 136 (3), 288-298, 2020 | 55 | 2020 |
The checkpoint for agonist selection precedes conventional selection in human thymus G Verstichel, D Vermijlen, L Martens, G Goetgeluk, M Brouwer, N Thiault, ... Science immunology 2 (8), eaah4232, 2017 | 52 | 2017 |
Human Immunodeficiency Virus nef Gene Expression Affects Generation and Function of Human T Cells, But Not Dendritic Cells B Verhasselt, E Naessens, C Verhofstede, M De Smedt, S Schollen, ... Blood, The Journal of the American Society of Hematology 94 (8), 2809-2818, 1999 | 51 | 1999 |